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13 Cards in this Set
- Front
- Back
What is the characteristic appearance of both Neisseria gonorrhoeae and N. meningitidis?
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Gram neg, kidney shaped diplococci
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Dexcribe the sugar fermentation patterns of N. gonorrhoeae and meningitidis?
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N. gonorrhoeae ferments only glucose whereas N. meningitidis ferments both glucose and maltose.
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What enzyme common to both N. gonorrhoeae and N. meningitidis allows them to colonize mucosal surfaces?
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IgA protease
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Name the most common pathologic manifestations of infection by N. gonorrhoeae.
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Purulent urethritis, cervicitis, epididymitis, pelvic inflammatory disease, neonatal conjunctivitis, disseminated gonococal infection.
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Which growth media is used for the isolation and )identification of N. gonorrhoeae?
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Thayer-Martin vancomycin, colistin, and nystatin(VCN) media.
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What are the most common complications in men of gonococcal urethritis?
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Epididymitis, prostatitis, urethral strictures.
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Identification of Gram neg diplococci in urethral discharge within which cell type is adequate for the diagnosis of gonorrhea in men?
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Neutrophils
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What are the major long term complications of N. gonorrhoeae induced pelvic inflammatory disease?
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Sterility, ectopic pregnancy, abscess, peritonitis, perihepatitis(liver capsule)
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What syndrome caused by N. gonorrhea involves perihepatitis?
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Fitz-Hugh Curtis. Patients complain of upper right quadrant pain and tenderness.
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Describe the symptoms of both forms of disseminated gonococcal infection.
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1. Fever, petechial lesions and arthralgias with erythematous macules over arms and legs that become hemorrhagic painful pustules over 2-3 days.
2. Monoarticular large joint septic arthritis(painful swelling of one knee) |
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How is N. gonorrhoeae treated?
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Ceftriaxone or a fluoroquinolone. Prophylaxis for neonatal conjunctivitis with AgNO3 or erythromycin into both eyes immediately after birth.
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What other bacterial coinfection must be considered in treating N. gonorrhoeae infections?
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Chlamydial infectiuon is a common coinfection with gonorrhea, so antibiotic treatment should cover both organisms.
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Which part of N. gonorrhoeae undergoes antigenic variation making it difficult to completely eradicate or develop a vaccine?
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Pili, outer membrane proteins(Opa), lipooligosaccharides(LOS).
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