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8 Cards in this Set
- Front
- Back
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Describe the morpholgy and special characteristics of Listeria?
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Smal Gram + bacillus, facultative intracellular, beta-hemolysis, catalase positive, tumbling motility at room temperature.
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What is unique about the growth characteristic of Listeria?
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It frows well in cold temperature(4-10C)
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What is the most prominant virulence factor in Listeria?
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Listeriolysin O toxin penetrates host cells phagocytic vacuole to facilitate entry into the cytoplasm.
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What is unique about the mechanism in which Listeria infects cells?
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Listeria has the ability to spread from cell to cell without entering the extracellular environment by using an actin polymerization propulsion system.
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What diseases are caused by Listeria?
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Meningoencephalitis, sepsis, infections in pregnancy and gastroenteritis.
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What patient populations are typically affected by Listeria?
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Pregnant women, newborns of infected mothers, elderly and immunosuppressed patients. It is a facultative intracellular organism and requires an intact cell mediated immunity to clear.
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How is Listeris transmitted?
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Most commonly via unpasteurized dairy meats and vegetables. Also transplacental spread during delivery.
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How is Listeria treated?
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Ampicillin(with gentamicin for serious cases or trimethoprim-sulfamethoxazole, for penicillin allergic patients. It is always resistant to cephalosporins.
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