Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
|
What drugs are associated with warm autoimmune hemolytic anemia. Of these, which drugs are associated with haptens? Which drugs generate autoantibodies?
|
Penicillin and quinidine are hapten forming. Alpha methyl dopa generates autoantibodies.
|
|
|
What test is positive in warm autoantibody disease?
|
Direct antiglobulin(Coombs) test
|
|
|
Cold autoimmune hemolytic disease has an acute and chronic form. What infections are associated with the acute form. What type of neoplasm is associated with the chronic form.
|
Acute form is associated with mycoplasma pneumoniae and infectious mononucleosis(Epstein Barr virus(EBV). Chronic form is associated with lymphoid neoplasms.
|
|
|
Cold autoimmune hemolytic disease has an acute and chronic form. What infections are associated with the acute form. What type of neoplasm is associated with the chronic form.
|
Acute form is associated with mycoplasma pneumoniae and infectious mononucleosis(Epstein Barr virus(EBV). Chronic form is associated with lymphoid neoplasms.
|
|
|
How is the autoantibody in Grave's disease different from other autoantibodies?
|
The autoantibody in Grave's disease, thyroid stimulating immunoglobulin(TSI), actually binds and activates the TSH receptor.
|
|
|
What type 2 disease is mediated by an autoantibody that shares the same target as exfoliatin(Staph toxin in scaled skin syndrome)?
What region of the autoantibodies attaches to the antigen in type 2 reactions? What region binds the complement? |
Pemphigus vulgaris
IgG or IgM attaches to the antigen at their Fab region and attaches complement at their Fc region. |
