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28 Cards in this Set
- Front
- Back
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Catalase? Staph Strept |
Staph postive (facultative anaerobe) Strep neg (aerotolerant anaerobe) |
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STREPtococcus pyogenes STAPHYlococcus auerus (Growth, virelence factors, disease) |
STREP pyogenes: (beta, cat pos,)(cell wall has Group A polysacc, Fc receptor-gprotein, M protein, streptokinase)(impetigo, strep, wound infections, STSS nectrozing fas)(complications: glomerneph, rheutmatic fever)
STAPHAureus: (gold hemolyti , cat neg,)(cell wall has Fc receptor. Bacterium produces superantigens, nuclease, protease etc.)(impetigo, SSSS, food poisoning, boils, STSS) |
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Disease by s auerus |
Food borne intoxication SSSS STS |
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Streptococcua species? And hemolytic of each? |
Viridans strep: alpha Steep pyognees (groupA): beta Strep pneumonia: alpha |
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Hemolysis lyse RBC The 3? |
Alpha: green due to release of RBC (VIRDIANS AND PNUENMONIA) Beta: complete hemolysis (GAS AND PYOGENES) Gamma: no hemolysis |
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What cause strep throat aka streptococcus pharyngitis? |
Strep pyogenes |
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Strep throat complications "sequelae"? |
Acute rheumatic fever (M protein) Acute post streptococcal glomerulne |
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Virulencce factors of STREP pyogenes (which is a disease cqused by Group A Strep)? |
M PROTEIN: intf with phagoctosis by breakdown of c3b complex (opsonin) C5A: inhibits phagocyte recruiment SPE: (toxins) 1)Superantigens responsible for scarlet fever, 2)TSS, 3)necrosis ●Spe bing to MHC 2 molecules and T cell receptor (cytokine storm)
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How many litees lfuid exhanhed I na day? |
9L |
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Enterotoxin Cytotoxin |
Watery diarrhea Bloody diarrhea |
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Cholera Orginated? Toxin type? ID? |
Contaminated water (pump) or food Enterotoxin ( high secretion of Cl-> Na+) High (bc acid sensitive) |
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Shigella Epidemiology? Id? Toxin? Species? |
Direct contact Moves cell to cell Low id Enterotoxin or shiga toxin (because of s dysenteriae species) which causes HUS |
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E coli Pathovers (pathogenic virulences)? Epidimology? Id? Antibiotics? |
Pathovars: 1) ETEC (enterotoxigenic e coli --chller like toxin) and 2) EHEC (enterohemorrhagic e coli) aka STEC (Shigatoxin producing e coli) //HUS BLOCKS PROTEIN SYN DEATH///SHIGA TOXIN DAMAGE ENDOTHEL/ meat manure contaminated water food Low id no antibiotics |
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Giardiasis Pathogen type? Id? Resover? Forms? Fatty stool wash hands |
Prtozoa Low id Animal Trophozite and cyst! |
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Trophozoite Form? Location is Forms? Survive enviero? |
Growing feeding form Small intestien Does not survive enviro |
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Cyst Form? Formed when? Id? Survive enveri? |
Dormant survival form As parasitw slowly passes out of GI tract Low id Yes 2 month! |
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1 cyst release how many trophizitws? |
2 |
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RNA disease DNA disease |
Hepatitis C and retrovirus HPV, Hepatitis B, herpes, E-B |
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Direct oncoviruses Defn and types? Indirect oncovirsus Ddfn and types? |
Viruse encode oncogenes HPV, some herpes Chronic infec, mistake in dna replication leds to mutation Hepatis C |
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Tumor supressor genes: P53 Rb |
P53: ties together DNA damage and apotosis Rb: inhibits progression of cell cycle from G1 to S phase |
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HPV Type virus? Envel or non envel? Causes? Integrate gene? Oncogene types and function? |
DsDNA non enveloped with capsid Causes warts and ALOT cancers!! Usualy does not To inhibit tumor supressor genes E6 binds amd degrades p53, prevent cell death E7 does same to Rb, removes brakes from cell cycle |
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HPV INFECTIONS TYPES productive Nonproductive |
Productive: keeps cell in undiff state so cant make L1 and L2 (turn off check points and make divide more) Non-productive: integration (rare because needs over expression of e6 and 7) leads to cell continusly dividing |
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Vitually 100 % cercic cancer associated WITH? |
HPV |
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HCV: indirect!!! Virus type? Envel or not? Infects? Symptoms? Leads to fibrosis Drug therapy? Vaccine? |
SSRNA Envel with lipid around capsid Main liver cells Jaundice and liver enzymes in blood Yes. iFN and ribavirin (nucleoside analog-side effect incorportad in gene) No plus treatment $$$$ But treatment repairs itself from cirrhosis not HCC |
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Nucleic types? ●HPV non envel ___ (INDERECT) ●HCV evel.________(direct) family Flavivirdae ●Influenza envel _______ ●herpes enveloped___large ●ebola enveld non seg _______ ●MERS-CoV |
HPV. dsDNA HCV. SS(+) RNA Inflienza (-) ssRNA Herpes. dsDNA Ebola. (-) SsRNA MERScoV. |
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Influenza Infection type? Part of resp tract? Nucleic acid? Types? And who they infect? |
Acute Upper and lower RNA type A (diff animals resovier is birds) B and C (human only) Type A: amanatidine and Rimantidine Type B and A: relenza and tamiflu |
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HERPES Types of infection? Nucleic acid? HSV1? HSV2? Where it goes latent? Reactivation of virsus? |
Persistent latent Large dsDNA Oral mainly Gentile mainly (can get birth) Nuerons around epithel. Cells travel up intial site infec Initiates lytic replication in neuron Travel down //Lyti virus works on meds// |
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Strepytococcus pneumonia |
Diplococcus Virulence capsule |
