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11 Cards in this Set
- Front
- Back
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What are the two types of light chain?
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Lambda and Kappa
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When this enzyme is combined with antibody it produces two identical FAB fragments and one Fc fragment.
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Papain
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The only antibody to cross the placenta:
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IgG - therefore most abundant antibody in newborns
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Which two immunoglobulins can activate complement?
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IgG and IgM
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The immunoglobulin that opsinizes:
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IgG
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The main immunoglobulin produced early in the primary response:
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IgM
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This antibody forms a pentamer and requires a J chain:
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IgM
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This immunoglobulin mediates immediate (anaphylactic) hypersensitivity
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IgE
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Which two immunoglobulins have a J chain? Which one has a secretory component?
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IgM and IgA - only secretory IgA has a secretory component
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Mutations in these henes arrest development of lymphocytes and result in SCID
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RAG-1 and RAG-2
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In this process, the same assembled Vh gene can sequentially associate with different Ch genes so that different Ig classes are produced.
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Class switching
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