Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
28 Cards in this Set
- Front
- Back
|
What is the morphology of all anaplasmataceae?
|
aerobic G- coccobacilli
obligate intracelular pathogens |
|
|
where do anaplasmataceae replicate?
|
insides WBC's
in intracytoplasmic vesicles= morulae |
|
|
What is there reservoir for E. Chaffeensis?
|
horses, deer, dogs, ticks
|
|
|
What is the vector for E. Chaffeensis?
|
lone star tick
|
|
|
what disease does E. Chaffeensis cause?
|
human monocytic ehrlichoiosis
|
|
|
what cells does E. Chaffeensis affect?
|
monocytes and macrophages
|
|
|
What is the presentation of HME caused by E. Chaffeensis?
|
high fever, HA
macular rash |
|
|
What are the labs common in E. Chaffeensis infection?
|
leukopenia
thrombocytopenia elevated CRP increased ESR mild serum transaminase elevation |
|
|
Where is E. Chaffeensis most common?
|
south eastern USA
|
|
|
Where is Anaplamosis Phagocytophium most common?
|
Wisconsin, michigan, upstate NY
|
|
|
what is the vector for Anaplamosis Phagocytophium?
|
blackleddged deer tick
western blacklegged tick |
|
|
What type of cell does Anaplamosis Phagocytophium infect?
|
PMN's
|
|
|
what are the complications of E. Chaffeensis?
|
liver damage
lung damage brain damage |
|
|
What is the morphology of Coxiella Burnetii?
|
small aerobic
G- pelomorphic bacilli |
|
|
What is the infectious form of Coxiella Burnetii?
|
the small cell variant
|
|
|
What is the obligate intracellular parasite form of Coxiella Burnetii?
|
Large cell variant
|
|
|
What is the phase I antigen of LPS O of Coxiella Burnetii?
|
wild type, more resistant to phagocytosis
and more virulant |
|
|
What is the phase II antigen of LPS O of Coxiella Burnetii?
|
this is a deletion mutant, easier to kill
|
|
|
Where is Coxiella Burnetii most common?
|
world wide, but mostly in:
Montana, NM, CO, UT, NA, IW, SD |
|
|
What is the vector for Coxiella Burnetii?
|
ticks
|
|
|
What is the main way to get Coxiella Burnetii?
|
inhalation of oganisms
|
|
|
Who is at highest risk of getting Coxiella Burnetii?
|
farmers, vets, lab workers
|
|
|
What disease does Coxiella Burnetii cause?
|
Q fever
|
|
|
What is the presentation of Q fever?
|
proliferation of alveolar macrophages
HIgh fever severe HA atypical pneumonia granulomas in liver |
|
|
What happens in Chronic Q fever?
|
subacute endocarditiis due to Coxiella Burnetii
|
|
|
What do you diagnose Q fever?
|
Serology-
Phase II antigens show up within 2 weeks, while phase I antigens take longer to show up |
|
|
What is the Serology for Acute Q fever?
|
IgM to phase 1/2
IgG to phase 2 |
|
|
What is the serology for Chronic Q fever?
|
increased IgG and igA to phase 1
decline in Ig's against phase 2 |
