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35 Cards in this Set
- Front
- Back
Intact, infectious virus particles
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Virions
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Two types os symmetry viruses can have
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Helical/Rod shaped
Spherical |
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Clustering of capsid proteins discernible by electron microscopy
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Capsomere
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Viral genome and capsid
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Nucleocapsid
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What determines what cell types the virus can infect and what is this called?
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proteins on virus surface
TROPISM |
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Helical viruses require a...
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Envelope
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What are the 6 classes of viruses
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ssDNA
dsDNA + RNA Retroviruses - RNA dsRNA |
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7 families of DNA viruses
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hepadna
herpes adeno pox papova parvo irido |
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Only DNA virus that is not double stranded
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Parvovirus
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What DNA viruses are not linear
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Papova
hepadna both are circular |
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Where do DNA viruses replicate
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All in nucleus except POX
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Enveloped DNA viruses?
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hepadna
pox herpes irido |
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RNA Viruses
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Toga
Corona Flavi Retro Picorna Calici Reo Arena Bunya Filo Orthomyxo Paramyxo Rhabdo (all + viridae) |
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Where do RNA viruses replicate
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Cytoplasm except for influenza- negative sense RNA which replicates and makes mRNA in nucleus
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What vir polymerase is most error prone
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RNA-dep RNA polymerase b/c no proofreading activity
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Herpesviridae
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ds DNA virus w/ envelope
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Hepadnaviridae
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ds DNA virus w/ envelope. Circular DNA
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Papovaviridae
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ds DNA, w/o envelope, Circular DNA
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Adenoviridae
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ds DNA, w/o envelope
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Parvoviridae
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ss DNA w/o envelope
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Poxviridae
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DNA virus, complex w/ envelope. Replicates outside nucleus and does not have icosahedral capsid
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Togaviridae
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single stranded RNA, +, enveloped
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Coronaviridae
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single stranded RNA, +, enveloped
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Flaviviridae
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single stranded RNA, +, enveloped
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Retroviridae
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single stranded RNA, +, enveloped
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Picornaviridae
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single stranded RNA, +, w/o envelope
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Caliciviridae
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single stranded RNA, +, w/o envelope
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Reoviridae
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ds RNA, no envelope
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Arenaviridae
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ss RNA, -, w/ envelope
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Bunyaviridae
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ss RNA, -, w/ envelope
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Filoviridae
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ss RNA, -, w/ envelope
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Orthomyxoviridae
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ss RNA, -, w/ envelope
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Paramyxoviridae
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ss RNA, -, w/ envelope
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Rhabdoviridae
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ss RNA, -, w/ envelope
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Virus Life Cycle
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Attachment
Penetration (fusion(e)/endocytosis(e/n) Uncoating Gene Expression Gene Replication Assembly Release/Egress (budding/fusion (e)) |