Microbiology U3.12 Ch 9 - Gene Expression Mutation

Front 1

changes are ____ in the DNA

Back 1

mutations

Front 2

2 types of DNA point mutations

Back 2

substitution - deletion/insertion

Front 3

point mutation is ____, ____ or ____ of a few bases (in DNA)

Back 3

addition - deletion - substitution

Front 4

3 types of substitutions of point mutations

Back 4

missense mutation - nonsense mutation - silent/same sense mutation

Front 5

missense mutation causes change in a ____ amino acid

Back 5

single

Front 6

type of mutation that changes a normal codon into a stop codon

Back 6

nonsense mutation

Front 7

type of DNA mutation that alters a base but does not change the amino acid

Back 7

silent/same sense mutation

Front 8

in deletions/insertions of DNA mutations, there is a ____ in which the entire chain sequence of ____ ____ is changed

Back 8

frameshift - amino acids

Front 9

DNA mutations affect ____ expression

Back 9

gene

Front 10

degeneracy (redundancy) of the DNA code affects ____ mutations

Back 10

point

Front 11

in DNA mutations, the wild type is considered the ____ & non-____ sequence

Back 11

original - mutated

Front 12

sickle-cell anemia is a ____ mutation in point mutations

Back 12

missense

Front 13

in point mutations, change of a single nucleotide in the DNA's template strand leads to the production of an abnormal ____

Back 13

protein

Front 14

addition or loss of a nucleotide pair in a gene may produce ____ mutations

Back 14

frameshift

Front 15

insertion or deletion of 3 nucleotides (is/isn't) ____ frameshift & will cause extra or missing ____ ____

Back 15

is - amino acid