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23 Cards in this Set
- Front
- Back
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antigen
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any substance, that causes the production of antibody-mostly proteins but can include some carbohydrates and nucleoproteins
- foreign or non-self |
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antibody
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protein made in response to an antigen and binds specifically to the antigen that caused its production
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Bacterial Antigens (immunogens)
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Antigenic Determinants (Epitopes)
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Epitope : sequence of amino acids within a protein recognized as foreign
AMI : specific antibodies made in response to each epitope and attach to epitope. |
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Antibody Monomeric Structure
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Immunoglobulin Classes
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Why do plasma cells secrete different isotypes of antibody with same idiotype?
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Different isotypes access different body compartments
blood (IgM, IgG, IgA) tissue fluid (IgG, IgA) secretions (dimeric IgA) fetus (IgG) skin and membranes (IgE) |
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Activation of B Cells
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Clonal Selection and Differentiation of B Cells
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Results of Antigen-Antibody Binding
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Differentiation of T and B Cells
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Differentiation of T and B Cells
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M Cells
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Activation of CD4 T Helper Cells
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Activation of CD4 T Helper Cells
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CTL's Destroys Virus Infected Cells
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TCR on CTL recognizes viral epitopes displayed by MHC I molecules on surface of infected cells
Tc destroys target cells with perforin and granzymes Cell induce to apoptosis (programmed cell death) Only target cell is destroyed |
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Cell Mediated Immunity (Chart)
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Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)
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Antibody Response
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Types of Adaptive Immunity
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Serum Proteins
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Serum Proteins
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Humoral and Cellular Immuntity
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