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17 Cards in this Set
- Front
- Back
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A 5 yo presents with a 1 day cough, respiratory difficulty, nasal discharge and slight fever. The weather has been cold. A x-ray shows hyperinflation and peribronchiolar infiltrates. What might she have?`
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RSV
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What are common findings on PE of someone with RSV?
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fever, respiratory distress, rhinorrhea, expiratory and inspiratory wheezes, hyperinflation, atelectasis, crackles
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What is a common finding on an ABG in someone with RSV?
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low pO2 and oxygen sat
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What family of viruses is RSV in?
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paramyxovirdae
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What are the characteristics of RSV?
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enveloped, -ssRNA coding for 10 proteins, helical nucleocapsid
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What are the envelope proteins on RSV?
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1) F = fusion protein
2) G = glycoprotein |
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What are the two antigenic types of RSV?
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A and B
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Is RSV stable in the environment?
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no it can only survive a few hours
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What are peak months of RSV spreading?
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November to April with peak infectivity in Feb and Jan
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what is the most commonly infected age group with RSV?
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2-6 months
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Once infected with RSV how long does it incubate? Where does it incubate? Where does it go after incubation?
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1) 2-8 days
2) nasopharyngeal epi 3) goes to bronchioles 1-3 days later |
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What antibody may play a role in RSV infection?
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IgE
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What factors contribute to the pathogenesis of RSV infection?
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immune complexes, IgE and histamine
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What is bronchiolitis? what results?
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inflammation of terminal bronchioles, necrosis, sloughing off of epi in bronchioles
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Why does wheezing and hyperinflation during an RSV infection occur?
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because the bronchioles are swollen and impede air leaving the alveoli resulting in wheezing when are slowly escapes and hyperinflation when air can't escape
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How is RSV infection treated?
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nothing unless severe, then use oxygen, ribavirin, and/or IV immune globin
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Children with depressed immune system, heart defects or premature infants infected with RSV are at risk for what?
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serious pneumonia and encephalopathy
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