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17 Cards in this Set

  • Front
  • Back
What are Actinomycetes?
G+ bacteria with branching filaments resemling fungal hyphae.
What are two medically important Actinomycetes?
A. israelii (anaerobic)
Nocardia asteroides (aerobic)
Is person-to-person transmission of Actinomyces or Nocardia possible?
NO
Where do A. israelii reside?
Normal flora of oral cavity
What are the oxygen requirements of A. israelii?
Obligate anaerobic
How does A. israelii appear microscopically?
Sulfur granules surrounded by neutrophils.
Do sulfur granules contain sulfur?
NO, their yellowish appearance only resembles sulfur.
How can one be infected with A. israelii?
Trauma to the face of mouth
Human bite
Poor dental hygiene
What are three clinical manifestations of A. israelii?
Pus containing sulfur granules
Nontender abscesses, typically in the head and cervical region
Drainage through sinus tracts
How is Actinomyces treated?
Penicillin
Where is Nocardia found?
Soil
How is Nocardia usually contracted?
Inhalation of aerosolized particles
What are the oxygen requirements of Nocardia?
Obligate aerobic
What property does Nocardia share with Mycobacterium tuberculosis?
Both are acid-fast
Which one stains more weakly: M. tuberculosis or Nocardia?
Nocardia stains more weakly with acid-fast reagents than M. tuberculosis.
What are two clinical manifestatins of Nocardia?
Pneumonia
Abscess formation in various organs following pneumonia.
How is Nocardia infection treated?
Trimethoprim-sulfamethoxazole.