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20 Cards in this Set
- Front
- Back
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A 40 yo has a 2 month history of intermittent fever, chills, cough with green sputum, weakness, weight loss, chest pain, SOB and headache. He also has COPD. What might he have?
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Nocardia asteroides
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Someone infected with N asteroides would have what findings on PE?
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fever, tachycardia, tachypnea, unilaterally decreased breath sounds, weakness of upper extremities
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What would be seen in the blood work of someone with N asteroides?
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low Hct, low pO2
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A chest x ray of someone with N asteroides would show what?
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extensive nodular and cavitary disease in particular segment of lung
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Does mycoplasma typically cause B/L or unilateral disease?
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B/L
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Is pneumcoccal pneumonia typically chronic or acute?
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acute
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How is N asteroides characterized?
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filamentous (beaded) aerobe that is weakly gram + and weakly acid fast.. they are rod shaped... fucking nath
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What group does N asteroides belong to?
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aerobic actinomyces
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How long should a culture suspected of containg N asteroides be cultured?
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up to 4 weeks
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What bacteria taken from the lung and looked at under the microscope may be confused with hyphae producing fungi?
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N asteroides
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How is N asteroides transmitted?
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inhalation of contaminated dust
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Who is at risk for developing nocardiosis?
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people taking immunosuppressive drugs, corticosteroids, and AIDS
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What organism spreads along lymphatics and produces Madura foot? It seen in tropical countries in agriculture workers
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N asteroides
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How do N asteroides evade phagocytic destruction?
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prevent phagosome-lysosome fusion and acidification of the phagosome
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Are N asteroides obligate intracellular bacteria?
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no they are facultative intracellular bacteria
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Where do N asteroides proliferate in the host?
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alveolar macrophages
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What constitute the main immune mechanisms for controlling N asteroides?
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macrophages and T lymphocytes
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What lung pathology occurs in someone with untreated N asteroides?
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inflammatory endobronchial masses or diffuse pneumonitis and abscess, cavitation can occur
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What is a common site of N asteroides in a patient that is immunocompromised? What are symptoms?
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CNS. develop headaches, lethargy, confusion, seizures, sudden onset of neurologic deficit
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How is N asteroides treated?
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prolonged use of sulfonamides like TMP-SMX, can use amikacin or imipenem
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