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21 Cards in this Set
- Front
- Back
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A 20 yo girl is sick with fever, rash, cough, conjunctivitis, coryza. PE shows rash on face, trunk and somewhat on extremities and red spots on palate. The she is unaware of immunizations. What might they have?
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Measles
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What is another name for measles?
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rubeola
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What are the lesions in the mouth of someone infected with rubeola called? How does the rash on the extremities and trunk look?
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1) koplic spots
2) red and blotchy rash |
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What type of rashes are common with meningococcemia?
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petechial rashes
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Do scarlet and typhoid fever present with cough and coryza? What are the lesions seen with these infections?
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1) no
2) strep causes red papilla on tongue and typhi has rose spots on torso |
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What family of viruses is measles in?
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paramyxoviridae
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How are virions of measles viruses called?
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pleomorphic
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What are the characteristics of measles virus?
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pleomorphic, enveloped, -ssRNA
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How many serotypes does measles virus have?
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one
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How is the measles virus transmitted?
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respiratory droplets
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What cells does the measles virus infect first?
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epi cells of upper respiratory tract
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After primary replication where does the measles virus go?
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goes in blood to reticuloendothelial cells and replicates in them
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After secondary replication where does the measles virus go and what results?
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viremia occurs and virus infects WBCs, spreads to skin and lung
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What cell type is characteristic if seen in someone with measles virus?
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multinucelated giant cells with inclusion bodies in nucleus
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What is the incubation period of measles virus preceding rash?
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7-8 days
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When is the measles virus contagious?
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first respiratory symptoms until 4 days after onset of rash
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After prodromal fever where does virus attack?
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vascular endothelial cells of dermal capillaries causing rash and Koplik spots
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If purpura are seen in someone with measles virus what can be said?
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this is the height of the illness with blood leaking from capillaries
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What is the treatment for measles virus?
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none
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Will a vaccine to measles virus be affective if given 48 hours after exposure?
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yes up to 72 hours
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What can measles progress to in weak patients?
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giant cell pneumonia and subacute slcerosing panechephalitis
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