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7 Cards in this Set

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  • Back
microorganisms or microbes...certain worms like round and flat(helminths insects like mosquitos fleas or ticks....
a fabric merchant of Delft Holland who ground lenses...Anton van Leeuwenhoek
abiogenesis....w/out parent organisms....meaning that there was a belief that organisms arose from decaying matter with out pre-existing parent cells
redi- (1668)...experiment using maggots and flies to prove that they did not generate just from decaying meat

needham- (1745-1748)...thought he demonstrated spontaneous generation when he saw microbes growing in both broths that were boiled and sealed with corks.

Spallazani- variation of needhams broth by varying lengths of time boiled in flasks..sealing some leaving some open. Said boiling killed organisms while those open had growth from organisms in the air, disputing any idea of spontaneous generation.

Pasteur- silenced "vital life forces" critics when he made swan flasks left entirely open to spontaneous generation for microbes trapped in neck of flasks.
Germ theory of disease was described by Fracastoro as concept that contagions or germ were responsible for infection or disease and methods that they spread from person to person
aka koch's procedures....
where specific microorganisms can be related to specific infectious disease.

postulate 1.-same microorganisms are present in every case of disease

2-m.o. r isolated fr: tissues od dead animal and a pure culture is made

3-m.o. fr: pure culture r put n2 a healthy animal. the disese is reproduced

4- identical m.o. r isolated and recultivated Fr: tissue specimens of experimental animal
Semmelweiss- reduced incidence of puerperal (childbed) fever in Austrian hospitals w/handwashing w/ chlorine water.

Lister- pioneered antiseptic surgery using carbolic acid (phenol) mist in infirmarys. (phenol is also cancer causing)

Koch- established *Bacillus Anthracis* as a pathogen for anthrax. he made steps for finding specific disease for specific infection

Metchnikoff- described phagocytosis

Abbe- developed the oil emersion lens and the Abbe condenser

Ehrlich- synthesized a "magic bullet" for syphilis

Fleming- went on trip and left bacteria cultures on bench and came back to find mold in one. The mold killed bacteria that came near it...creating penicillium