Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/55

Click to flip

55 Cards in this Set

  • Front
  • Back
killed vaccines induce
humoral immunity
live/attenuated vaccines induce
humoral immunity AND cell-mediated immunity
live/attenduated vaccines
VZV
Adenovirus
Smallpox
Sabin (oral, poliovirus)
Yellow fever
MMR

(Vaccines Are So Simple Yet Mandatory)
live vaccines should not be given to
immunocompromised pts. (or close contacts)
killed vaccines
Rabies
Influenza
Salk (IM, polio)
HAV

(RIP Always)
egg-based vaccines
Flu
mmR
Yellow fever

FRY an EGG
negative-stranded RNA viruses
Arenaviruses
Bunyaviruses
Paramyxoviruses
Orthomyxoviruses
Filoviruses
Rhabdoviruses

Always Bring Polymerase Or Fail Replication

[(-)RNA viruses require transcription of (-)RNA to (+)RNA via RNA polymerase]
segmented RNA viruses
Bunyaviruses
Orthomyxoviruses - 8 segments of (-)ssRNA
Arenaviruses
Reovirsuses

(BOAR)
picornaviruses
Poliovirus
Echovirus
Rhinovirus
Coxsackievirus
HAV

PERCH on a peak (pico-)
virus:

orchitis = enlarged testes
aseptic meningitis
sterility (after puberty)
mumps

(also parotitis)
virus:

SSPE
encephalitis
giant cell pneumonia
measles

(also head to toe rash with Koplik spots on buccal mucosa)
3 C's of measles
cough
coryza ("head cold")
conjunctivitis
influenza A prophylaxis (2)
amantadine

rimantidine
MOA of amantadine and rimantidine
inhibit M2 viral protein --> inhibition of viral uncoating
influenza A and B treatment (2)
oseltamivir

zanamivir
MOA of oseltamivir and zanamivir
neuraminidase inhibitors --> virus can't leave infected cell
incubation period of rabies virus
3 weeks to 3 months
arboviruses (3)
flaviviruses
bunyaviruses
togaviruses

(Flea Bites Today)
yellow fever transmitted by
Aedes mosquito
virus:

black vomitus
jaundice
Councilman bodies (liver)
yellow fever
in addition to shingles, VZV can also cause (2)
pneumonia
encephalitis
HHV-8 transmitted via
sexual contact
nodes especially affected by EBV
posteriorauricular
atypical lymphocytes in EBV are
cytotoxic T cells
Tzanck test assays for (3)

looks for
HSV-1
HSV-2
VZV

multinucleated giant cells
HAV is a ______virus
picornavirus
HBV is a ______virus
hepadnavirus
HCV is a _______virus
flavivirus
HEV is a ______virus
calicivirus
hepatitis virus:

common cause of IV drug use hepatitis
HCV
HDV requires
HBsAg
hepatitis virus:

causes water-borne epidemics
HEV
hepatitis virus:

high mortality rate in pregnant women
HEV
hepatitis viruses:

predispose patients to chronic active hepatitis, cirrhosis, and hepatocellular carcinoma
HBV
HCV
best test to detect active HAV
IgM HAVAb
continued presence indicates HBV carrier state
HBsAg
provides immunity to HBV
HBsAb
positive during window period of HBV
HBcAg
indicator of recent HBV disease
IgM HBcAb
indicator of HBV transmissibilty
HBeAg

(BEware)
indicator of low HBV transmissibility
HBeAb
HIV envelope proteins (2)
gp41

gp120
HIV nucleocapsid protein
gp24
sensitive or specific:

ELISA for HIV
sensitive
sensitive or specific:

Western blot for HIV
specific
all babies born to HIV+ mothers have _______ detectable at birth
anti-gp120 Ab's
AIDS diagnosis:

CD count

CD4:CD8
<200

<1.5 (normal 2.0)
genotype of pts. immune to HIV
homozygous for CCR5 mutation
genotype of pts. who have slow course of HIV infection
heterozygous for CCR5 mutation
genotype of pts. who have rapid progression to AIDS
CXCR4 mutation
first HIV antigen detectable in pts. serum
p24 antigen
EBV in AIDS pt. causes (2)
oral hairy leukoplakia

non-Hodgkin's lymphoma
HIV gains access to the CNS via
macrophages
signs of HIV encephalitis (2)
microglial nodules

multinucleated giant cells
normal vs. pathologic prions
normal prions - alpha helices

pathologic prions - beta pleated sheets