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14 Cards in this Set

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Who was responsible for the initial work on anaphylaxis?

Charles Richet and Paul Portier

Hypersensitivity

an immune response that injures tissues. Can be categorized into 4 groups

Autograft

tissue transplant from elsewhere in the body

Zenograft

tissue transplant from an animal

desensitization

causes immune system to produce IgG to the offending allergen. Involves injection of extremely dilute concentration of antigen over time

anaphylaxis

a destructive immune response

Immune complexes

results from IgG or IgM antibodies binding to soluble antigens. circulating immune complexes can lodge in blood vessel wall in skin, joints, kidneys, and other tissues with small blood vessels.

Farmer's Lung

result of immune complex

Serum sickness

systemic immune complex disease caused by passive immunization

Arthus Reaction

localized immune complex disease that occurs following injection of antigen into a previously immunized individual who already has a high lever of circulating antibodies

Allografts

tissues of donor andrecipient are not genetically identical.

Privilegedsites

organs such as corneas,testis, uterus>

SCID

a. severe combined immunodeficiency disorder resulting fromhematopoietic stem cells of bone barrow not producing t and b lymphocytes.Lethal in children.

Agammaglobulinemia

a. few or no antibodies produced