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29 Cards in this Set

  • Front
  • Back
Endemic mycoses
true pathogens restricted geographically and have the ability to cause serious illness in otherwise healthy individuals
Opportunistic mycoses
not true pathogens because they only cause disease in immunosuppressed patients
subcutaneous mycoses
fungi that involve the skin, subcutaneous tissue and lymphatics
superficial and cutaneous mycoses
fungal infections limited to the skin and skin structures
fungi are prokaryotic or eukaryotic
eukaryotic
multicellular fungi
mold
unicellular fungi
yeast
what kind of sterol makes up the cell membrane
ergosterols
what do fungi cells have that mamallian cells do not have
cell walls
do fungi require oxygen?
yes strict aerobes
what are multicellular mold filaments called
hyphae/ plural mycelium
fungi that can grow as either molds or yeasts
dimorphism
what is the most common form for pathogenic fungi
yeast form, mold form is usually environment
asexual reproductive structures
conidia
what can lead to dangerous fungal infections by otherwise benign fungi
immunosupression
what are the main barriers to fungal infection
skin and mucal barriers
what properties of the skin destroy fungi
low PH, cell turnover and dessication
what drug can cause opportunistic fungi to proliferate
antibiotics
what does tissue reactions to fungi depend on
duration of infection, tissue infected and species of fungus
what is important for eliminating fungal infections
low grade inflammatory reactions
what is the primary mechanism that are critically important in eliminating fungi
neutrophil phagocytosis
what disorders can increase fungal infections
chronic granulomatous disease or myloperoxidase deficiency
what happens to fungi that are to big to be digested
they can be destroyed by phagocytes lining up and secreting lysosomal enzymes
what is the most important immune function in eliminating fungi
t cell mediated immunity
what determines the outcome of an infection
virulence, size of the infection and adequacy of host defenses
what is used for direct observation of fungi
10% potassium hydroxide
what binds to chitin
calcoflour white
antibodies are useful for detecting what
endemic mycoses, but not for opportunistic
antigens in body fluid are useful for what
sensitive and specific for the diagnosis of several fungal infections