Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
Allergen
|
Allergy, hypersensitivity - an exaggerated, misdirected expression of immune responses to an allergen (antigen).
|
|
|
Autoimmunity
|
Abnormal responses to self Ag
|
|
|
Immunodeficiency
|
Deficiency or loss of immunity.
|
|
|
Cancer
|
Results from a lack of surveillance.
|
|
|
Immediate Hypersensitivity
|
Anaphylaxis, atopic allergies such as hay fever, asthma
IgE mediated, involves mast cells, basophils and allergic mediators. |
|
|
Antibody-Mediated
|
Blood group incompatibility, pernicious anemia; myasthenia gravis
IgG, IgM antibodies act upon cells with complement and cause cell lysis, includes some autoimmune diseases |
|
|
Immune Complex-Mediated
|
Systemic lupus erythematousus, rheumatoid arthritis, serum sickness, rheumatic fever
Antibody-mediated inflammation; circulating IgG complexes deposited in basement membranes of target organs; includes some autoimmune diseases |
|
|
T-Cell-Mediated
|
Infection reactions; contact dermatitis, graft rejection, some types of autoimmunity such as diabetes.
Delayed hypersensitivity and cytotoxic reactions in tissues. |
|
|
What is hay fever?
|
A seasonal rhinitis resulting from an allergic reaction to pollen.
Rhinitis is an inflammation of the mucous membrane lining the nose (usually associated with nasal discharge) |
|
|
Sensitizing Dose
|
On first contact with allergen, specific B cells form IgE which attaches to mast cells and basophils, generally no signs or symptoms.
|
|
|
Provocative Dose
|
Subsequent exposure with the same allergen binds to the IgE-mast cell complex
|
|
|
What is a universal donor?
|
Type O
|
|
|
What is the universal recipient?
|
Type AB
|
