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16 Cards in this Set
- Front
- Back
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Penicillin G
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G+
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Penicillin V
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G+ - penicillinase susceptible
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Methicillin
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Semi-synthetic - evades penicillinase - resistant organisms develop
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Amoxicillin
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Semi-synthetic - Effective against many G - penicillinase susceptible
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Augmentin
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Amoxicillin + clavulanic acid - broader spectrum - betalactamase inhibitors
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Vancomycin
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Glycopeptide - inhibits cell wall synthesis - Narrow spectrum - last line of defense against S. aureous - resistant strains developing
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Isoniazid (INH) Ehambutol
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Inhibits mycolic acid synthesis - anti-TB - long regimen/compliance issues - given in combination to reduce TB resistance
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Tetracycline
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Interferes with protein synthesis - broad spectrum - effective against intracellular parasites - disadvantages - GI upset, photosensitivity, tooth discoloration in children
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Sulfonamides
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Inhibits folic acid synthesis - Broad spectrum - Used for UTI - bacteriostatic
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Trimethoprim/sulfamethoxazole combo
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Inhibit folic acid synthesis - Synergistic - used together, concentration of drugs can be reduced
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Acyclovir
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Nucleotide analog
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AZT
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Antiretroviral
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Protease inhibitors
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HIV
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Interferons
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Interferes with the spread of virus - hepatitis C and cancer applications
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MetronidazoleDamages DNA
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Antoprotozoan, works on anaerobix bacteria
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Amphotericin B
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Causes injury to plasma membrane - used for systemic fungal infections
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