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13 Cards in this Set

  • Front
  • Back

Streptococcus pneumoniae

Knife shaped pairs, short chains, die in presence of O2, grow in blood agar


Pathogenic strains cause large capsules, major virulence - capsule cause sickness


Up to 50% carry as normal flora, occurs when cells are aspirated into lungs, inflammatory


response


*Increased drug resistance

Bacillus


1. Bacillus anthracis


a. (3) types: Cutaneous, Pulmonary,


Gastrointestinal


2. Treatment


3. Bacillus cereus

- Gram +, endospore forming, habitat in soil, source of antibiotics


1. central spores - develop outside body capsules & exotoxins


a. black sores - spore thru skin / shock,edema - spores inhaled /


edema, bowels - ingested spores


2. Penicillin, tetracycline, ciprofloxacin, vaccines


3. Airborne, grows in food, ingestion, spores live thru heating, 24-hr bug

Clostridium


1. Clostridium difficile


2. Clostridium botulinum & (3) causes

- Gram +, spore-forming, anaerobic, infections & food intoxication


1. Resident of colon, non-invasive, produce enterotoxins, damage


intestines


2. Common in soil/water, produce botulism toxins - blocks release of


acteylcholine preventing muscle contraction / Food poisoning,


infant = honey, wound

1. Clostridium perfringens


2. Clostridium gastronenteritis


3. Clostridium tetani & (3) symptoms

1. Causes gangrene (dead tissue - black area), blood flow ceases


Veg. cells ferment muscle carbs & decompose muscle proteins = lg amounts of gas under skin (crackling sound)


2. Spores contaminate food, consumed toxin produced in intestine, rapid recovery


3. Tetanus, common resident of soil and GI tract, uncontrollable


muscle contractions (toxin tetanospasmin inhibit muscles) Trismus - lockjaw / Opisthotonus - arching of back / Spasmodic inhalation - seizures in diaphragm (reduces ventilation)





Listeria monocytogenes

- Gram +, coccobacili, non-endospore, virulent no capsules, resist cold, heat, salt, pH, primary soil/water (intracellular bacteria - hides in cell)


*Affects brain and meninges

Corynbacterium diptheriae


(2) Stages of disease:


a. Local infection


b. Diptherotoxin Production

- Gram +, irregular bacilli


a. upper resp. tract inflammation


(pseudomembrane caused asphyxiation)


b. toxemia (heart and nerves)

Mycobacterium


1. mycobacterium tuberculosis


a. secondary TB


b. extrapulmonary TB

- Gram +, acid-fast, aerobes, produce catalase


1. airborne respiratory droplets, caused


granulomas of bacilli surrounded by WBC's


a. reactivation, tubercles expand drain into


bronchial tubes & upper tract


b. during secondary bacilli disseminate to lymph


nodes, kidneys, brain and meninges

Mycobacterium leprea


Forms:


1. Tuberculoid


2. Lepromatous

- Strict parasite, causes leprosy - starts in skin


moves to nerves (Hansen's disease)


1. superficial infection w/o skin disfigurement


2. deeply nodular infection, causes


disfigurement

1. Bacterial meningitis


2. Neisseria


3. Neisseria meningitidis

1. Meninges of brain and spinal cord, cross blood-brain barrier


2. Gram -, strict parasites, resident of mucous membranes, do not


survive long outside host


3. Capsules, pili, enter thru bloodstream into cranial circulation,


endotoxins cause hemorrhage and shock


4. Strictly human found, pili, can cause sterility, can be spread to


newborns during birth



1. Enterobacteriaceae Family


2. Virulence Factors (H,K,O,En,Ex)

1. Enterics, Gram -, soil/water, enterotoxins,


coliforms (lactose and non lactose)


2. H - flagellar / K - capsule / O - cell wall /


Endotoxin/ Exotoxin

Escherichia coli


a. enterotoxigenic


b. enteroinvasive


c. enteropathogenic


d. enterohemorrhagic

a. fimbrae - stimulates secretion & fluid loss


b. inflammatory disease of lg intense


c. wasting from infantile diarrhea


d. damage kidney

1. Salmonella


2. Typhoid Fever & 5 F's


3. Shigella

1. S. enteritidis, touching reptiles, fomites (fecal route)


2. Caused by salmonella typhi, in small intestine lead to diarrhea and to


septicemia, (Flies, Food, Fingers, Feces, Fomites) Fecal to oral route


3. S. dysenteriae - most common, GI incapacitating dysentery, invades lg


intestine, inflammatory response, endotoxin and exotoxins, erodes


lining in intestines, fluid replacement

Yersinia pestis


a. sylvatic


b. urban


c. flea vector

Black plague, Gram -, capsule, endotoxin, coagulase, murine toxin


a. contact with wild animals


b. domestic animals and infected humans


c. bacteria replicates, coagulase blood clotting that block esophagus (no path to stomach, still hungry keep biting)