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10 Cards in this Set

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1. Bacterial Disease Classified by?


2. Physiological Properties:


a. catalase


b. oxidase


c. peroxidase



1. Airborne, Foodborne, Waterborne, Soilborne, Arthropodborne, Physical contact (STD, contact, animal)


a. Hydrogen peroxide > water


b. Water > hydrogen peroxide


c. Breakdown peroxidase - caused by tissue


damage

Staphylococcus aureus (S. aureus)


1. Enzymes: C,H,S,D,L,P


2. Toxins: H,L,E,E,T



- Gram positive, capsule, anaerobe, extreme salts, pH, and temp


1. Coagulase-coagulates blood / Hyaluronidase-promote invasion / Staphylokinase-digests blood clots / Dnase-digests DNA /


Lipases-bacteria colonize(oily skin) / Penicillinase-inactivates penicillin


2. Hemolysins-Lyse RBC's / Leukocidin-Lyses neutrophils & macrophages / Enterotoxins-Act in GI tract / Toxic Shock Syndrome





1. Staphylococcal Disease - 1


a. (F,F,C,I)


2. Staphylococcal Disease - 2


b. (O,B,E)

1. Localized cutaneous infections invade thru skin


a. Folliculitis-inflammation of hair follicle > Furuncle-boil >


Carbuncle-cluster of furuncles


Impetigo-bubble like swelling break and peel away (newborns)


2. Systemic infections (into bone)


b. Osteomyelitis-infection in metaphysis forms abscess >


Bacteremia-bacteria from another infected site >


Endocarditis - into blood steam to heart

1. Staphylococcal Disease - 3


(3) Toxigenic diseases


2. S. Epidermidis

1. ) a. food intoxication - (heat enterotoxins) GI distress


b. Staphylococcal scalded skin syndrome -


Blisters then skin falls off


c. TSS - toxemia - shock - organ failure


2. lives on skin and membranes, endocarditis,


bacteremia, UTI

Catalase vs Coagulase Testing

Catalase + = Staph / - = Strep


Coagulase + = S. aureus / - = all other Staph

Streptococci


1. (2) Classification Systems

- Gram +, long chains, can form capsules, facultative anaerobe, sensitive to drying and disinfectants


1. Lancefield - based of cell wall anagens (surface marker indicator)


Hemolysis - ability to break down RBC


Alph = Complete breakdown


Beta = Partial breakdown


Gamma = No breakdown



Streptococci Skin/Throat Infections:


1. Impetigo


2. Erysipelas


3. Streptococcal pharyngitis



1. Superficial Lensions, highly contagious -


insects, poor hygiene, crowded living


2. Enters thru breaks in skin, can be superficial


or become systemic


3. strep throat

S. pyogenes


1. Virulence Factors


a. Surface antigens


1. C-carbohydrates 2. Fimbriae 3. M-protein


b. Extracellular toxins


1. Streptolysins 2. Erythrogenic toxin


3. Superantigens

- Flesh eating bacteria, Group "A" Strep, produces toxins, humans only, most serious, Causes impetigo or strep or pharyngitis


a. 1.) protect against lysozymes degrading cells 2.) adherence / 3.) contributes resistance to phagocytosis


b. 1.) hemolysins - cause cells and tissue injury 2.) red rash 3.) strong monocyte and lymphocyte stimulants, degrading different tissues

S. agalactiae

- Group "B", can be normal flora, resides in vagina and lg intestines, passed on thru birth

Typical Pneumonia

- Caused by several bacteria, most caused by Streptococcus pneumoniae not all