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43 Cards in this Set

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Facultative gram negative rods, non-lactose fermenting, produces H2S, and cultured in XLD medium

Salmonella spp.

Salmonella that can be seen in human colon only

S. typhi

Two species of Salmonella that cause enterocolitis, the invasion of epithelial and subepithelial tissue of large and small intestines. From infected egg and chicken

S. enteritidis and S. typhimurium

Species of Salmonella that causes typhoid fever due to Vi capsular antigen, allowing the organism to enter and multiply in Peyer's patches and then spread to reticulo-endothelial system.

Salmonella typhi

In typhoid fever, there is prediletion for invasion of the ______, which can result in establishment of the chronic carrier state

Gallbladder

Species of Salmonella that causes Septicemia, bacteremia which results in seeding of many organs with osteomyelitis, pneumonia, and meningitis as the most common sequelae. Commonly in patients with sickle cell anemia or cancer

S. choleraesuis

In week 1 of tyhoid fever, there is stepwise fever with relative bradycardia, anorexia, malaise, and bacteremia. Most important culture source is

Blood

In week 2 of typhoid fever, there are abdominal symptoms: abdominal pain, bloating, constipation, rose spots, hepatosplenomegaly, and jaundice. Most important culture sources are

Urine, the rose spots

In week 3 of typhoid fever, there is bleeding, ileitis, and pneumonia. Most important culture source is

Stool

In week 4 of typhoid fever, the patient may recover or die. Culture source

Bone marrow

A patient with typhoid ever past week 4 and is in a chronic carrier state has these culture sources

Bile, stool, bone marrow

Treatment for Salmonella spp.

Ceftriaxone, Ciprofloxacin


In Philippines: Amoxicillin, chloramphenicol, cotrimoxazole

Non-lactose fermenting gram-negative rods that do not produce H2S, are non motile, and cultured in XLD medium

Shigella spp.

Shigella invade which part of the GIT

Distal ileum and colon

Shigella that is the most common cause of bacillary dysentery

Shigella sonnei/Duval's bacillus

Shigella that causes the most severe form of bacillary dysentery and is the most common cause of epidemic dysentery

Shiella dysenteriae type I/Shiga bacillus

Treatment for severe cases of Shigella

Ciprofloxacin

Comma-shaped gam negative rods, motile, oxidase positive, cultured on thiosulfate citrate bile salts sucrose agar, with shooting star motility

Vibrio spp.

Vibrio found in human colon only

V. cholerae

Difference in transmission route between V. cholerae, parahaemolyticus, and vulnificus

V. cholerae- fecal-oral route


V. parahaemolyticus- contaminated raw seafood


V. vulnificus- trauma to skin especially in shellfish handlers or ingestion of raw shellfish

Vibrio cholerae causes cholera, producing watery diarrhea in large volumes, described as

rice water stools

Vibrio tahat causes gastroenteritis and wound infections

V. parahaemolyticus, V. vulnificus

DOC for cholera

Tetracycline

Treatment for V. parahaemolyticus and V. vulnificus

Minocycline plus fluoroquinolone or cefotaxime

Comma-shaped gram negative rods that are microaerophilic and grow well at 42C on Skirrows agar (prefers hot temperature)

Campylobacter jejuni

Most common cause of bacterial gastroenteritis

Campylobacter jejuni

Campylobacter jejuni produces histologic damage to the mucosal surfaces of the

Jejunum

Syndrome associated with Campylobacter jejuni where there is antigenic cross-reactivity between oligosaccharides in bacerial capsule and glycosphingolipids on surface of neural tissues

Guillan-Barre syndrome

Campylobacter jejuni is associated with Reiter's syndrome, triad of which is

"Can't pee, can't see, can't climb a tree"


Urethritis


Uveitis


Arthritis

Treatment for Campylobacter jejuni

Erythromycin for severe disease

Curved gram-negative rod, microaerophilic, urease positive

Helicobacter pylori

Most common urease positive bacteria

"PucK HU"


Proteus mirabilis


Klebsiella pneumoniae


Helicobacter pylori


Ureaplasma urealyticum

Helicobacter pylori damages ____ of the gastric mucosa

Goblet cells

Thanks to Helicobacter pylori's urease, they can produce large amounts of _____ to neutralize the stomach acid

Ammonia

H. pylori is associated with these 3 diseases

Peptic ulcer disease, gastric carcinoma, MALT lymphomas

Drugs used for H. pylori eradication

Tetracycline, Clarithromycin, Metronidazole, Amoxicillin

Facultative gram negative rods with large polysaccharide capsule and extended spectrum beta-lactamase activity in drug resistant strains. Urease positive

Klebsiella pneumoniae

Bacteria that causes necrotizing pneumonia with thick bloody sputum ("currant jelly" sputum)

Klebsiella pneumoniae

Most common cause of pneumonia in alcoholics

Klebsiella pneumoniae

Facultative gram negative rods, non-lactose fermenting, urease positve, with swarming motility/concentric growth

proteus mirabilis

Urease of Proteus mirabilis hydrolyzes the urea in urine to form ammonia, raising pH to produce alkaline urine and encouraging the formation of ______ composed of magnesium-ammonium-phosphate

Struvite stones

Proteum mirabilis is associated with complicated UTI associated with nephrolithiasis and _______ that form on renal calyces

Staghorn calculi

Treatment for Proteus mirabilis

TMP-SMX or ampicillin