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30 Cards in this Set

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  • Back
These gram - pleomorphic organisms differ in that one can make ATP when necessary while the other cannot. Both are obligate intracellular parasites.
Rickettsia - can make ATP
Chlamydia - cannot make ATP
Which pleomorphic Gram - does the following:
Cannot make ATP
Person to person spread
Endosome Replication (inclusion bodies)
Columnar Epithelium (mucus)

Eye, Lung, Genitals
Conjunctivitis, pneumonia, cervicitis
Which pleomorphic Gram - does the following:
Can make ATP
Needs arthropod vector
Cytoplasm Replication
Endothelium (blood vessels)
Seen with Giemsa Stain

Rash, Fever, Headache
Chlamydia Tx:
Rickettsia Tx:
Associated with the Weil felix Rxn
Extremely tiny gram - bacteria that does not have a PGL and no muramic acid
The leading cause of preventable blindness in the world.
Caused by Serotypes ABC.
Chlamydia Trachomatis
Primarily infects eyes and genitals.
Painless papule/ulceraton on the genital that heals spontaneously. Can also present with elephantiasis of the genitals with rectal strictures. After healing, Lymphadenopathy that break and drain pus.
(Painless to Painful)
Chlamydia Trachomatis
Lymphogranuloma Venereum
Serotype L1-L3
Cause non-gonococcal urethritis
Chlamydia Trachomatis
Ureaplasma Urealyticum

Tx:IM Ceftriaxone + doxycycline or azithromycin
Associated with the Chandelier Sign
PID due to Chlamydia Trachomatis infection. Vaginal examination reveals SEVERE cervical motion tenderness
Conjunctiva, urethritis, reactive arthritis occurring in men 20-40.
Autoimmune cross rxn associated with HLA-B27
Chlamydia Trachomatis
Reiter's Syndrome
Serotype D-K
Fitz-Hugh-Curtis Syndrome
Serotype D-K
Chlamydia Trachomatis
Neisseria Gonorrhea

Violin strings, liver capsule
Leading cause of Sexually transmitted bacterial disease.
Serotypes D-K Cause:
Inclusion Conjunctivitis
Infant Pneumonia
Reiter's Syndrome
Fitz-Hugh-Curtis Syndrome
Chlamydia Trachomatis
Infectious particle of Chlamydia
EB (Elementary Body)
Reticulate body = non-infectious
Causes of Atypical Pneumonia
Chamydia Psittaci
Chlamydia Pneumoniae
Mycoplasma Pneumoniae

Dry cough, no sputum, normal lung exam, CXR slight infiltrates
Causes an interstitial type of pneumonia and is associated with exposure to contaminated parrots and parakeets and other domestic birds
Chlamydia Psittaci
"Psittacosis, Ornithosis"
Tx: Doxycylin
Previously known as the TWAR agent, it is a common cause of sore throats and interstitial pneumonia
Chlamydia pneumoniae
Transmitted by TICKS - Dermacentor Andersoni/Variabilis (wood/dog TICK), infection results in a petichial rash with involvement of the palms and soles
Rickettsia Rickettsii
"Rocky Mountain Spotted Fever"
Associated with overcrowding and transmitted by the human body LOUSE, this organism causes EPIDEMIC Typhus
Rickettsia Prowazekii
Known as Murine or ENDEMIC typhus, this bacteria is spread by the FLEA with Rodents as the Reservoir
Xennopsylla Cheopis (Rat Flea)
Rickettsia Typhi

Milder than Epidemic Typhus
Rickettsia Prowazekii
Weil-Felix RXN
pour pt serum over proteus Vulgaris covered beads. Abs in pt serum will stick to beads - Agglutinate = + test.
Associated with Flying Squirrels, LICE/Louse, and EPIDEMIC Typhus. Rash spares palms, soles and face.
Reickettsii Prowazekii

Tx: Tetracycine, Chloramphenicol
Brill-Zinsser Disease
When pts have latent reactivation infection with Rickettsii Prowazekii due to initial recovery without antibiotic therapy. Dx: IgG Abs
Known as Scrub Typhus or Tsutsugamushi Fever, this is spread by bite of larvae (chiggers) of mites leaving a scab at the bite site.
Rickettsia Tsutsugamushi
Known as Trench Fever this LICE bourne organism is not an obligate intracellular orgainsm and relapses occur in 5 days.
Bartonella Quintana
Transmitted by the bite, scratch, or lick of an infected cat, resulting in low grade fever and a characteristic enlargement of lymph nodes for several weeks.
Bartonella Henselae
"Q-Fever" Has an endospore form that allows transmission via respiratory route from cow placentas and hides. Pneumonia with NO rash, Weil test (-)
Coxiella Burnetii
Infection in immunocompromised can result in Bacillary Angiomatosis, cranberry like pustules resembling Kaposi sarcoma.
Bartonella Henselae
Transmitted by the Dog TICK which bite humans. Causes Ehrlichiosis which presents like RMSF but only 20% of the time with a rash.
Ehrlichia Chaffeensis (Human)
Ehrlichia Canis (Dog)