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30 Cards in this Set
- Front
- Back
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These gram - pleomorphic organisms differ in that one can make ATP when necessary while the other cannot. Both are obligate intracellular parasites.
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Rickettsia - can make ATP
Chlamydia - cannot make ATP |
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Which pleomorphic Gram - does the following:
Cannot make ATP Person to person spread Endosome Replication (inclusion bodies) Columnar Epithelium (mucus) Eye, Lung, Genitals Conjunctivitis, pneumonia, cervicitis |
Chlamydia
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Which pleomorphic Gram - does the following:
Can make ATP Needs arthropod vector Cytoplasm Replication Endothelium (blood vessels) Seen with Giemsa Stain Rash, Fever, Headache |
Rickettsia
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Chlamydia Tx:
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Tetracycline,Doxycylin
Erythromycin Ceftriaxone |
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Rickettsia Tx:
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Doxycyclin
Chloramphenicol |
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Associated with the Weil felix Rxn
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Rickettsia
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Extremely tiny gram - bacteria that does not have a PGL and no muramic acid
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Chlamydia
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The leading cause of preventable blindness in the world.
Caused by Serotypes ABC. |
Chlamydia Trachomatis
Primarily infects eyes and genitals. |
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Painless papule/ulceraton on the genital that heals spontaneously. Can also present with elephantiasis of the genitals with rectal strictures. After healing, Lymphadenopathy that break and drain pus.
(Painless to Painful) |
Chlamydia Trachomatis
Lymphogranuloma Venereum Serotype L1-L3 |
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Cause non-gonococcal urethritis
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Chlamydia Trachomatis
Ureaplasma Urealyticum Tx:IM Ceftriaxone + doxycycline or azithromycin |
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Associated with the Chandelier Sign
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PID due to Chlamydia Trachomatis infection. Vaginal examination reveals SEVERE cervical motion tenderness
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Conjunctiva, urethritis, reactive arthritis occurring in men 20-40.
Autoimmune cross rxn associated with HLA-B27 |
Chlamydia Trachomatis
Reiter's Syndrome Serotype D-K |
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Fitz-Hugh-Curtis Syndrome
Serotype D-K |
Chlamydia Trachomatis
Neisseria Gonorrhea Violin strings, liver capsule |
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Leading cause of Sexually transmitted bacterial disease.
Serotypes D-K Cause: Inclusion Conjunctivitis Infant Pneumonia Urethritis PID Epididymitis Reiter's Syndrome Fitz-Hugh-Curtis Syndrome |
Chlamydia Trachomatis
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Infectious particle of Chlamydia
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EB (Elementary Body)
Reticulate body = non-infectious |
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Causes of Atypical Pneumonia
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Chamydia Psittaci
Chlamydia Pneumoniae Mycoplasma Pneumoniae Viruses Dry cough, no sputum, normal lung exam, CXR slight infiltrates |
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Causes an interstitial type of pneumonia and is associated with exposure to contaminated parrots and parakeets and other domestic birds
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Chlamydia Psittaci
"Psittacosis, Ornithosis" Tx: Doxycylin Erythromycin |
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Previously known as the TWAR agent, it is a common cause of sore throats and interstitial pneumonia
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Chlamydia pneumoniae
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Transmitted by TICKS - Dermacentor Andersoni/Variabilis (wood/dog TICK), infection results in a petichial rash with involvement of the palms and soles
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Rickettsia Rickettsii
"Rocky Mountain Spotted Fever" |
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Associated with overcrowding and transmitted by the human body LOUSE, this organism causes EPIDEMIC Typhus
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Rickettsia Prowazekii
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Known as Murine or ENDEMIC typhus, this bacteria is spread by the FLEA with Rodents as the Reservoir
Xennopsylla Cheopis (Rat Flea) |
Rickettsia Typhi
Milder than Epidemic Typhus Rickettsia Prowazekii |
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Weil-Felix RXN
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Rickettsia
pour pt serum over proteus Vulgaris covered beads. Abs in pt serum will stick to beads - Agglutinate = + test. |
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Associated with Flying Squirrels, LICE/Louse, and EPIDEMIC Typhus. Rash spares palms, soles and face.
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Reickettsii Prowazekii
Tx: Tetracycine, Chloramphenicol |
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Brill-Zinsser Disease
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When pts have latent reactivation infection with Rickettsii Prowazekii due to initial recovery without antibiotic therapy. Dx: IgG Abs
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Known as Scrub Typhus or Tsutsugamushi Fever, this is spread by bite of larvae (chiggers) of mites leaving a scab at the bite site.
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Rickettsia Tsutsugamushi
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Known as Trench Fever this LICE bourne organism is not an obligate intracellular orgainsm and relapses occur in 5 days.
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Bartonella Quintana
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Transmitted by the bite, scratch, or lick of an infected cat, resulting in low grade fever and a characteristic enlargement of lymph nodes for several weeks.
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Bartonella Henselae
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"Q-Fever" Has an endospore form that allows transmission via respiratory route from cow placentas and hides. Pneumonia with NO rash, Weil test (-)
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Coxiella Burnetii
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Infection in immunocompromised can result in Bacillary Angiomatosis, cranberry like pustules resembling Kaposi sarcoma.
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Bartonella Henselae
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Transmitted by the Dog TICK which bite humans. Causes Ehrlichiosis which presents like RMSF but only 20% of the time with a rash.
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Ehrlichia Chaffeensis (Human)
Ehrlichia Canis (Dog) |
