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36 Cards in this Set

  • Front
  • Back
6 characteristics of life
communication
reproduction
metabolism
evolution
differentiation
movement
Hooke
microorganisms
van Leeuwenhoek
bacteria
Cohn
endospores
bacteriology
winogradsky
chemolithotrophy
beijerinck
enrichment culture
koch
pure culture
solid media
tuberculosis
koch's postulates
pasteur
spontaneous generation
koch's postulates
1. MO present in all diseased and absent from all healthy
2. pure culture
3. cause disease in healthy
4. reisolated
polysaccharide
glycosidic bond
nucleic acids
phosphodiester bonds
D-amino acids
peptidoglycan
L-amino acids
proteins
cyanobacteria
produce O2 gas
quinolone antibiotics
target DNA gyrase
endosymbioant hypothesis
current cells: chimera (1+ organism)
nucleus: archae-like
mitochondria & chloroplast: eukaryote-like
proteins and polypeptides
polypeptide: chain of AAs
proteins: 1+ polypeptide
racemic mixture
pasteur & tartaric acid crystals, when d & l mixed, no rotation
ester bonds
lipids
flagellum
rotation: filament (protein-flagelin), hook, motor (run by PMF)
pilus
reproductive, for DNA transfer, proten--pilin, attachment, pathogenesis
fimbriae
short pili for adherence
capsule
=slime layer=glycocalyx
contains sugars and aas
prevents things from getting inside and exposure to immune cells, virulence factor
peptidoglycan
bacteria only (except mycoplasm), cleaved by lysozyme (after NAM), longer in G+ because peptide interbridge
penicillin
(b-lactam antibiotic) inhibits transpeptidase, prevents cross-link formation --> lysis. works on growing cells, links to AA irreversibly, but does not affect G-
G+ cell wall
teichoic acids and lipoteichoic acid
G- cell wall
thin PG
outer membrane: LPS (lipid + polysaccharide), lipoprotein (attach to PG), porin
LPS
lipid A
core polysaccharide
O-specific polysaccharide (O-antigen)
KDO
is an endotoxin
catalase and superoxide dismutase
in strict aerobes
polymyxins
membrane structure/function. pmf disturbed
sulfa drugs
folic acid metabolism. DNA precursor synthesis inhibited
penicillin
peptidoglycan synthesis. transpeptidiase inhibited
quinolones
replication. dna not made
rifampin
(dna dependent rna polymerase inhibitor) transcription. rna not formed by rna polymerase
chloramphenical
tetracycline
translation. 50/30 s ribosomal subunit
translation reagents
mrna, ribosomes, aa~trna, protein factors, gtp