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7 Cards in this Set
- Front
- Back
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2 major surface glycoproteins of influenza
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neuraminidase and hemagglutin
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Genetic material of influenza
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RNA
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Antigenic drift occurs in which influenza strains?
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A and B
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Uptake of the viral particle into a host cell is mediated by which surface protein?
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HA
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What causes un-coating of the influenza viral particle?
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H+ influx; leads to release of viral genome
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Mechanism of drugs amantadine and rimantadine
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inhibit viral un-coating by preventing H+ influx
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Mechanism of oseltamivir and zanamivir
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neuraminidase inhibitors; prevent removal of sialic acid inhibitors = virus aggregates and cannot spread. neuraminidase removes sialic acid from virus particles
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