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15 Cards in this Set
- Front
- Back
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porcelain filters used to filter( remove) bacteria
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charles chamberland
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some filtrates remained infectious???
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dmitri ivanovsky
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"contagium vivium fluidium" contagious living fluid
Later coined the name virus(meaning poison or venom) |
martinus beijerinck
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prior to 1930's : lack of technology needed to :
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isolate
propagate observe and analyze was not available |
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crystallizied the first virus(TMV), consisted of protein and RNA
viruses first obsered with an electron microscope |
wendell stanley
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certain inherited traits seem to be passed from parent to offspring as discrete hereditary : particles"
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mendel's particles: gregor mendel
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genetic material of some virus was DNA
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hershey and chase
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contain a single type of nuclei acid , either DNA or RNA
contain a protein coat(capsid) around the nucleic acid is antigenic/immunogenic (stimulates antibody production) some virus have an envelop around the protein coat mutiply inside the living cells( virus cant synthesize the protein of generate ATP) viruses take over the metabolic activity of host cells important for clinical control: difficult to disrupt viral replication without interfering with host cell function. |
general characteristic and structure of viruses
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shapes:
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helical/ spiral
icosahedral (20 sided polyhedron) enveloped complex |
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phage tail fibers attach to specific receptors on bacteria
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attachment/ adsorption
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phage release enzyme->
Lysozyme: dissolves part of the bacteria cell wall tail sheath contracts and drives phage core through the cell wall |
penetration
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viral DNA takes over the machinery of the host cell and begin producing viral DNA and structural components
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biosynthesis
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phage DNA assembles into complete viruses
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maturation/ assembly
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phage lysozyme breakd down bacteria cell wall and mutiplied phages are released
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release/ lysis
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the time from adsorption to release
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burst time
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