Microbio-Fungus Pathogenesis And Sx

Front 1

this superficial skin infection occurs when this lipophilic fungus feeds on skin oil and removes stratum corneum layer

sx: red, brownish, blotchy, scaly, painless, hypopigmented or hyperpigmented skin of upper body of non suntanned individuals?

Back 1

tinea versicolor

Front 2

what will tinea versicolor look like in suntanned or dark skinned people?

what can this infection develop into?

Back 2

pinkish white patches on thes kin of upper body

can develop into atopic dermatitis on back and upper trunk (itchy papules and pustules)

Front 3

what is a mold feeding on stratum corneum of HANDS AND FEET

sx: soliatry brownish black, nonscaly flat, painless MACULES

what does the color of lesions come from?

Back 3

tinea nigra

color of lesions comes from black color of fungus

Front 4

what is an infection of hair resulting in white, mycelial and nodular swellings along axis of hair shafts

sx: soft, white painless nodules that crust on skin of hair or genitals and is easy to break off?

what does color od lesion come from?

Back 4

white piedra

color is from white fungus

Front 5

what is an accumulation of large masses of epithelial debris containing fungi and/or bacteria and fungi in EXTERNAL AUDITORY MEATUS

sx:
chornix infection of external ear with pain, itching, pain, inflammation and loss of hearing

Back 5

otomycosis

Front 6

what is invasion of glabrous skin of FACE, chin and upper lip of kids and females but NOT mustahce and beard of adult male

sx: scaling, annular or cirularlesions w/ raised margins and papules
*pruritis, burning and erythema

Back 6

TInea faciei

Front 7

what is a mycelia that grow into pores around hair shafts and stratum corneum of skin. it produces edema, leukocytic infiltrations

sx. mild superficial type by scaling lesions on bearded areas of face and neck

deep pustular type has deep folluclar pustules on bearded ares of face, neck

what can these follicular pustules form into?

Back 7

Tinea barbae

can form info nodular kelids and kerions w/ alopecia and scarrin

Front 8

what is also known as gray patch ringworm?

what do infected hairs look like?

how do lesions begin and what do they develop into?

what type of rxn can occur. what does allergic rxn cause?

Back 8

TInea capitis ectothrix

infected hairs, have a pale scaly grayish and breaksoff

coalesced papules in ring form can develop into kerions and keloids

allergix rxn producing dermatophytids can occur. this leads to alopecia, kertaomycosis

Front 9

what is a form of tinea captitis that occurs when myclea interact with scalp proteins?

what does this produce

Back 9

Tinea favosa

develops into dead cell masses in mats of hair and yellowish brown cupshaped skin crusts(SCUTULA) with loss of hair and scarring

Front 10

this infects the horny layer of skin and spreads circularly. center clears and rings of inflammtion on glabrous skin go from dry and scaly patches to pustural and crusty hyperkeratosis

what are two types

Back 10

tinea corporis

annular and vesicular

Front 11

this starts from a nail injury. Enzyems that interact w/ skin and nail proteins produce a soft friable keratin that loosesn nail and THICKEns plate of fingernails or toenails

Back 11

tinea unguium

Front 12

what is a nail invasion restricted to white patches or pits on surface of nail?


what is a nail infection where edges are first involved and become brittle, friable and thickened w/ cracks

Back 12

leukonychia mycotica

invasive subungual dermatophytosis

Front 13

what is an infection from maceration of skin from occupational activity that results in:


*exfoliative, erythmeatous, scaly sheets of skin that become vesicular red circumscribed patches

Back 13

Tinea manuum

Front 14

what is jock itch?

what do lesions begin as and develop into?

what do old lesions become like?

Back 14

tinea cruris(moist area of groin)


begins as circular leion that develop into serpinginous, well marginated red lesions with raised borders and tiny vesicles


old lesions become leather like from intense itching

Front 15

athletes foot?

what promotes invasion of this fungus

describe lesions?

what are sx?

Back 15

tinea pedis


breakdown of host skin defenses promotes invasion

infects localized to keratinized skin

lesions are chornic papulosquamous

sx:
-intertriginous dermatitis(ppel soften and fissure b/w toes)
-vesicles or bullar on dorsal surface of foot that ulcerate and can cause secondary bacterial infection

Front 16

what is a hyphae that invaes subq tissue producing granulomas w/ allergic rxn

how does this organsim evade host defenses?

Back 16

Pseudallescheriasis


evades by depositing extracellular melanin and forming thick cell walls

Front 17

someone comes in with eumycetomas

(painless tumor like swelling in skin that ulcerates and can scar w/ woody disfigurement)

Back 17

Pseudallescheriasis

Front 18

patient presentw wibh bronchial pneumonia acompanied with bronchial colonization and fungus ball formation?

Back 18

pulmonary pseudallescheriasis

Front 19

what are other forms of pseudallescheriasis

Back 19

*sinusitis, otomycosis, meningitis, arthritis, osteomyelitis, endocarditis, endopthalmitis, keratitis, cut and subq

Front 20

this is a mycelial invasion resulting in local lesions in lymphatics containing neutrophils, macrophages and giant cells

fociaare circumscribed microabscesses surrounded by leukocyte?

where can this oranism infect?

Back 20

Sporotrichosis


1. lymphocutaneas
2. fixed cutaneous
3. mucocutaneous
4. pulmonary
4. extracutaneous

Front 21

this forms gelatinous types of lesions that develop into masses of yeasts

how will mucocatenous form present?

how will cutaneous candidiasis present?

how will ysstemic present?

Back 21

Candidiasis, with granulomas and possible allergic rxn

muco as thrush, glossitis, stomatitis, cheilitis, perleche, vaginitis,k balantitis, gatroenteritis and bronchitis

cutaneous as paroncyhia, diaper rash and onychomycosis


systemic as fever, HA, anorexia, myalgia,

Front 22

how can candidiasis be induced?

Back 22

iatrogenically following antibiotics or narcotic addiction

Front 23

what are yeasts seeded into blood?


what occurs in patiens on continuous ambulatory peritoneal dialysis from IV cath or machinery?

Back 23

Rhodotorulosis

Front 24

what are sx of rhodotorulosis?


can this be fatal?

Back 24

fever, hypotension, tachy, meningitis, chills

can be atal

Front 25

what is a yeast that multiplies in lung tissue w/ formation of hyaline membrane around cyst like granulomas containing an eosinophic exuadte in the alveoli?

Back 25

Pneumocystocis

Front 26

what are sx of pneumocystosis?

Back 26

fever, chills, nonproductive cough, chest pain, congestion, anorexia, sob, weight loss and development of INTERSTITIAL PLASM CELL PNEUMONIA in immunocompromised hosts(COTTON WOOL SPOTS)

Front 27

what is a capsular polysaccarid that results in depletion of complemetn and inefficient opsonization and inefficient phagocytosis?

what does it form in large numbers?

how is resolution of this?

Back 27

Cryptococcosis

forms granulomas with large number o encapsulatied yeast cells in clusters

SLLOW resolution leaving walled off granuloma in tissue

Front 28

what is the most frequently dx form of cryptococcosis?

what are other possible presetations?

Back 28

CNS (HA, fever, nausea, vomiting, lethargy, nuchal rigidity, photophobia, neck tenderness)

also:
-cutaneous
-mucocutaneous
-disseminated dz
-osseous

*involves swelling and pain b/c of granulomas

Front 29

what invades endothelial cells resulting in pyogenic suppuration and necrosis w/ release of fungal endotoxins

has presence of dsRNA mycoviruses

what type of tissue are lesions?


what are other types of infection?

Back 29

Aspergillosis

granulomas

infect:
-pulmonary
-disseminated
-iatrogenic

Front 30

patient has fever, dyspnea, edema, hemoptysis, and pleuritic chest pain and fungus balls?

Back 30

aspergillosis

Front 31

patient has rhinocerebral prptosis? what is possible dx

Back 31

-desseminated aspergillosis

Front 32

infection results in development of necrotic foci that is

-bronchitis
-trhush
-colitis
-cystic masses in skin

Back 32

Geotrichosis

Front 33

infection of nailr damages nail architecture with development of grooves and cavities but W/O thickening of nail plate

Back 33

onychomycosis

Front 34

fever, dyspnea, bronchitis and hempotptysis in patients w/ leukemia or lymphoma?

Back 34

Mucormycosis

Front 35

fever, HA cellulitis of nose, bilateral prpsis and swelling of brain in DM or leukemia

Back 35

rhinocerebral mucormycosis

Front 36

GI ulcers, diarrhea and peritonitis?

Back 36

abdoinal mucormycosis

Front 37

contamninated bandages presentw with abscesse and granulomas in skin of burn patients?

Back 37

Cutaneous murcormyosis

Front 38

debilitated patienst due to invasion of nose or paranasla sinuses ora s result of head trauma

Back 38

cNS mucormyocosis infection

Front 39

these hyphae directly invade blood vessels an cause necrosis, thrombosis and infarction w/ loss of artrial blood supply and can result in microabscesses in which eosinophils predomoinate as a sheath around hyphae

LEsions are necrotic and fibrotic w/ consistency o RUBBER.

mucormycotic infections are aggressive and are TRUE MEDICAL EMERGENCIES in immunosuprressed DM or neutropneic patients

Back 39

MUCORMYCOSIS

Front 40

YEast forms multiply in tissue resulting in PYOGENIC abscess formation w/ accumulation of neutrophil

what is cellular response dependent on?

Back 40

Blastomycosis

*severity of disease and vaires w/ infiltration of macrophages and histiocytes,lymphocytes and plasma cells or fibroblasts

Front 41

what is crab claw shadow?

Back 41

blastomycosis


lower lobe lung leison

Front 42

dry cough, chills, pleuritic pain, pneumonia, sore throat, myalgia fever and weight loss?

Back 42

primary pulmonary blastomycosis

Front 43

ulcerative subq nodules?


osteomyelitis or septic arthrirtis

Back 43

cutaneous blastomycosis


osseous blastomycosis

Front 44

with is a suppurative, neutrophil filled tisse with endospores w/ double refactile walles.

Fomration of granulomas produce cavities and nodules that result in scarring

Back 44

coccidioiodomycosis

Front 45

asymptomatic or with fever, chills, pleuritic pain, cough, anorexia and headaches referred to as VALLEY FEVER

Back 45

pulmonary coccidiomycosis

Front 46

Desert bumps

Back 46

allergic coccidiomycosis

Front 47

Desrt rhumatism

Back 47

arthrisis from coccidiomycosis

Front 48

solitary or mutliple necrotic granulomas and lesion with yeast infected monocytes and macrophages growin in bone marrow and disseminate the dz

Back 48

histoplasmosis

Front 49

fever, cough, loss of breath, bloody sputu, sweating, weight loss , malaise, cyanosis, hemoptysis, cavitation and penumonia

Back 49

severe pulmonary histoplasmosis

Front 50

oropharyngeal ulcer formation on mucous m embrnaes that become granulmatous?

Back 50

mucocutaneous histoplamsosis

Front 51

fever, anemia, meningitis, hepatsplenomaglay, leukopenia, septick shock and weight loss

Back 51

systemick histoplasmosis