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93 Cards in this Set

  • Front
  • Back
Acne

Agent: Propionibacterium acnes


Gr stain: Gr+ pleomorphic rods-diphteroids


Symptoms: Bacterial antigens+ fatty acids causes local inflammation.Anaerobic bacteria inhabits hair follicles and produce propionic acidOverproduction of sebum leads to clogging pores

Skin scaling dandruff

Agent: Yeast Malassezia



Scalded Skin Syndrome

Agent: Staphylococci


Symptoms: Peeling off the skin



Impetigo

Agent: Staphylococcus Aureus or Streptococcus pyogens


Symptoms: Skin lesions, small patches on the face and limbs, develops into pus-filled vesicles that itch (highly contagious)


Treatment: antibiotic-protein inhibitor (cephalexin)

Necrotizing fasciitis


"Flesh eating bacteria"

Agent: Streptococcus Pyogens


Symptoms: Rapid destruction of tissue, hyaluronidase: dissolves the connective tissue, Exotoxin A: acts as superantigen cause an immune response that is useless

Gangrene

Agent: Clostridium Perfinges


Symptoms: Blood supply to the tissuer is interrupted


Treatment: PCN, surgical removal, hyperbaric chamber

Dermatits

Agent: Pseudomonas aeruginosa


Gr negative aerobic


Symptoms: rash associated with swimming in pools


Treatment: antipseudomona b-lactame antibiotics

Warts

Agent: Virus-HPV (80 types)


Symptoms: transmitted by contact, sexual contact, and respiratory routs


Vaccine available


Treatment: liquid nitrogen, electrical current, burning with acids, laser treatment

Smallpox (variola)

Agents: Virus: Orthopoxvirus


Symptoms: skin lesions, pustules after 10 days


***First disease eradicated, vaccine discontinued

Chickenpox (varicella)

Agent: Virus, herpesvirus varicella-zoster ( human herpesvirus 3)


Symptoms: Skin lesions, virus remains latent in nerve cell near spine


Vaccine available

Shingles

Agent: Virus, herpesvirus varicella-zoster


Symptoms: latent virus of varicella reactivated by stress causes new outbreak

Herpes Simplex Type 1

Agent: HSV1


Symptoms: lesions in the oral mucous membrane "cold sores" or "fever blisters"

Herpes Simplex Type 2

Agent: HSV2


Symptoms: genital herpes, transmitted by sexual contact (antigenic makeup)

Measles (rubeola)

Agent: Virus


Symptoms: similar to common cold, rash on face and trunk, lesions in the mouth


Vaccine available

Rubella (German Measles)

Agent: Viral


Symptoms: Light fever, small red spots, fatal for pregnant women


Vaccine available (not for pregnant women)

Dermatomycoses

Agent: Fungus


Symptoms: fungal infection of the skin, nails, and hair. RIngworm fungus digest keratin

Candidiasis

Agent: Yeast candida albicans


Symptoms: Overgrowth of mucosal tissue when the normal microflora is suppressed. In newborns: whitish overgrowth in the mouth cavity


Treatment: miconazole, nistatin

Conjunctivitis (red eye)

Agent: Viral, Bacterial: haemophilus influenza and pseudomonads


Symptoms: Inflammation of the conjunctiva (mucous membrane that lines the eyelids and covers the eye ball)Source of infection: skin, upper respiratory tract and contact lenses.

Neonatal gonorrheal ophthalmia

Agent: Neisseria gonorrheae


Symptoms: Contracted as the infant passes through the birth canal


Treatment: Silver nitrate (no longer used)

Trachoma


(most often cause of blindness)

Agent: Chlamidia Trachomatis (intracellular parasite)


Symptoms: conjunctivitis, mechanical damage of cornea caused by in-turning of eyelashes


Treatment: Tetracycline

Acanthamoeba Keratitis

Agent: Protozoa


Symptoms: Inflammation, in later stage there is severe pain. Found in fresh water, tap water, hot tubs. Infection associated with contact lenses, damage cornea is susceptible to infection

Meningitis Agents

Bacteria: Streptococcus pneumonia, haemophylus influenza, Neisseria meningitides and 50 other species of bacteria


Viruses, fungi and protozoa as well

Meningitis Gr - or +?

Haemophylus influenza: Gr negative, found in children 6 months to 4 years


Neisseria Meningitides: Gr Negative cocci


Streptococcus pneumonia: Gr positive diplococcus (in children 1 month to 4 years

Meningitis Symptoms

-Sudden high fever and severe headache,


-vomiting


Inflamed spinal meninges: stiff neck, altered muscle control


-infection of the brain, or “encephalitis, can result in behavioral changes, coma and death-signs and symptoms may develop rapidly

Meningitis Treatment

Haemophylus-vaccine


Neisseria: Vaccine, treatment with PCN injections ASAP


Streptococcus: Vaccine recommended for infants under 2

Listeriariosis

Agent: Listeria monocytogenes


Gr positive rods


Symptoms: Infects animals and humans, ingestion of contaminated food, adults with compromised immune systems and pregnant women are more susceptible.


- Grows in central nervous system and placenta


Treatment: PCN G

Fungal Meningitis

Agent: Cryptococcus neoroformans; yeast


Symptoms: Found in soil, infection via inhalation, symptoms: headaches, stiff neckAffects especially aids patients

Naegleria meningoencephalitis

Agent: Naegleria flowleriamaeba


Symptoms: the pathogen infects the nasal mucous membrane and then the brain, 100% fatal

Arboviral encephalitis

Agent: arthropod borne virus; western equine encephalitis, eastern equine encephalitis,St. Luis encephalitis,California encephalitis,Japan B encephalitis


Symptoms: Chills, fever, headaches, and even death

West Nile Virus

Agent: Arbovirus


Symptoms: Body aches, headache, Polio-like paralysis and fatal encephalitis, infects birds and humans


Treatment: alleviate symptoms


Prevention: limit contact with mosquitoes

Creuzfeldt-Jacob

Agent: prions


Symptoms: altered behavior, dementia, memory loss, senility

Sheep Scrapie

Agent: prions


Symptoms: the infected animal scrapes itself against the wall, loss of motor control, death

Rabies

Agent: virus; rhabdovirus


Symptoms: Spasm of muscles, hydrophobia, biting behavior, excitability, increased salivation, difficulties in swallowing. Damaged to nervous system-death.


Treatment: 5-6 injections of vaccine + rabies immune globulin

Poliomyelitis (polio)

Agent: virus; polyovirus


Symptoms: Fever, sore throat,, nausea, virus multiplies in the motor cell, cell dies. 1% of infected will suffer paralysis


Vaccines: Salk vaccine (Europe), Sabun vaccine (US)

tetanus

Agent: Bacteria, clostridium tetani


Gr positive rod


Symptoms: tightening of the jaw and neck muscles, followed by fever and muscle spasm


Vaccine available (DTP)


Treatment: Human tetanus immunoglobulin, PCN

Botulism

Agent: bacteria, clostridium botulinim


Symptoms: Muscle remains relaxed, flaccid paralysis)


Treatment: antitoxin therapy

African trypanosomiasis "sleeping sickness"

Agent: protozoan; trypanosome brucei gambiense


Symptoms: decrease in physical activity and mental acuity, coma and death


Treatment-suramin in early stages, arsenic-based drug in late stages


Prevention: eliminating tsetse fly


Vaccine difficult to develop because ability of parasite to change protein coat

subacute bacteria endocarditis

Agent: Bacteria: a-hemolytic streptococci


Symptoms: bacteria grow on preexisting lesions, if not treated can be fatal within months, the microorganism enter the blood during tooth extraction or tonsillectomy


Treatment: prophylactic antibiotic treatment

Acute bacterial endocarditis

Agent: Bacteria, staphylococcus aureus


Symptoms: Transferred from original infection site to the heart ( traumatic injury of surgical procedure)Colonize hear valves ( vegetation)- cardiac malfunction. Rapid destruction of heart valves. If untreated fatal within few days

Plague (black death)

Agent: Bacteria, Yersinia pestis


Gr negative rod


Symptoms: enlargement of lymph nodes in armpit and groins,

Bubonic Plague

Agent: Bacteria


Symptoms: inflamed lymph nodes called buboes

Pneumonic plague

when bacterium for the plague spreads to the lungs


Treatment: Streptomycin, tetracycline

Rheumatic fever

Agent: bacteria, streptococcus


Symptoms: autoimmune reaction of the organism initiated by streptococcal infection. preceded by sore throat. Arthritis, fever, and nodules at joints. immune reaction is misdirected toward the heart valves

Anthrax

Agent: bacterial, Bacillus anthracis


Gr positive


Symptoms: Respiratory tract: pulmonary anthrax has 100% mortality, Gastrointestinal anthrax has 50% mortality, released exotoxin causes septicemia


Treatment: PCN (not effective against the toxin)

Gangrene

Agent: bacteria, clostridium


Symptoms: blood supply to the tissue is interrupted

Lyme disease

Agent: bacteria, borrelia burgdorferi


Symptoms: 1-expanding red rash that often resembles bulls eye, flu like symptoms, antibiotic effective. 2-neurological symptoms-facial paralysis, meningitis, 3-severe arthritis


Treatment: Doxycycline, PCN



Epidemic typhus

Agent: bacteria, rickettsis prowazekki


Symptoms: -transmitted by the human body louse, infection occurs when the feces of louse are rubbed into the skin when the host scrathes the bite. The microbe infects endothelia cells of vascular system, causing rapture of small blood vessels-hemorrhaging-red spot on the skinHigh fever, stupor and rash


Treatment: tetracycline and chloramphenicol

Mononucleosis (mono)

Agent: Virus, Epstein-barr


Symptoms: swelling of lymph nodes and spleen, proliferation of special type of lymphocytes, rapture of spleen possible


Treatment: relieving symptoms, rest

Yellow fever

Agent: arbovirus


Symptoms: Transmitted by mosquitoes ( Aedes aegypti)Symptoms: fever, nausea, vomitingYellowing of the skin as a result of liver damage


Prevention: control of mosquito population

Viral hemorrhagic fevers

Agent: Marburg virus


Symptoms: Headache, fever, internal and external bleeding

Lassa fever

virus


Symptoms: chest pain, hemorrhaging


Reservoir: rodent urine

Ebola

Virus


Symptoms: Capillary fragility, massive internal and external bleeding

AIDS

Virus, HIV


Infect T cells (type of white blood cells)Is a retrovirusIts components are two strands of RNA and the enzyme reverse transcriptase


-stages of HIV infection:category A: swollen lymph nodes category B: yeast infection of mouth, throat or vaginacategory C: al symptoms of aids – yeast infections, tuberculosis, kaposi’s sarcoma


Treatment: nucleoside reverse transcriptase inhibitors, protease inhibitors

Toxoplasmosis

Agent: protozoa, toxoplasma gandii


Human infection starts with eating raw meat of an infected animal or ingesting oocysts from urine or feces of infected cat


Symptoms: flu like symptomsInfection of pregnant women my result in death of the fetus or congenital defects(brain damage, blindness, and mental retardation

Malaria

Agent: protozoa, plasmodiums: p. falciparum, o. vivax, p. ovale, p. malarie


Symptoms: fever, chills recur every two to three days as erythrocytes lyse, anemia fatigue and jaundice


Treatment: chloroquine

The common cold

Virus: rhinoviruses and coronaviruses


Symptoms: Sneezing, nasal secretion, congestionPrimary infection is in the throat but can spread to the lower respiratory system and the middle ear.Immunity is accumulated during lifetime



Acute Otitis Media (ear infection)

Agent: streptococcus pneumonia, haemophilus influenza


Treatment: broad spectrum antibiotics

Streptococcal pharyngitis (strep throat)

Agent: bacteria, streptococcus pyogenes


Symptoms: Inflammation of throat mucous membrane, lymph nodes, difficulty swallowin


Treatment: PCN

Diphtheria

Agent: bacteria, corynebacterium diphteriae


Gr positive


Symptoms: sore throat, fever, grayish membrane in the throat (can block the passage of air)


Vaccine (DTP)


Treatment: PCN and erythromycin plus antitoxin

Pertusis (whooping cough)

Agent: bacteria, bordetella pertussis


Gr negative coccobacilli


Symptoms: affect the ciliated escalator system (prevent movement of mucus) infants can suffer from brain damage caused by severe coughing


Vaccine (DTP)

Influenza

Virus


Symptoms: chills, fever, headache and muscle aches


Vaccine with three most important strains

Tuberculosis

Agent: bacteria, mycobacterium tuberculosis


Gr positive


Symptoms: initial-minor cough and fever, later-difficulty breathing, chest pain, wheezing, coughing up blood, long term infection


Vaccine (BCG)


Treatment: streptomycin, isoniazid, rifampin, pyarain amid

pneumonia (pneumococcal pneumonia)

Agent: bacteria, streptococcus pneumoniae


Gr positive


Symptoms: Breathing difficulty, high fever, chest pan, bacteria can enter the blood stream and infect the meninges


Treatment: PCN

Legionellosis

Agent: bacteria, legionella pneumophila


Found in various natural environments, water lines, air conditioning systems, shower heads, decorative fountains



Histoplasmosis

Agent: fungus; histoplasma capsulatum dimorphic fungus


Symptoms: Infected lungs show lesions resembling tuberculosisIn US the diseases is localized in Mississippi and Ohio

Dental caries

Agent: bacteria, streptococcus mutans and filamentous bacteria actinomyces


Gr positive


Prevention: avoid sucrose, brush teeth and floss

Periodontal disease

Agent: bacteria, polymicrobial biofilm


Initial stage: gingivitis


Symptoms: swelling, bleeding of gingiva, formation of pockets


Advanced stage: periodontitis


Symptoms: tissue destruction, formation of deep pockets, build up of calculus( deposits of ca CO3), loosening of teeth, bone loss

mumps

Agent: virus, paramyxovirus


Disease of paratoid ( salivary) gland (located bellow the ears) Swelling of paratoid gland, fever, pains during swallowing


Vaccine (MMR)

Gastric ulcer

Agent: bacteria, helicobacter pylori


Lesions in the mucus membrane of the stomachSymptoms: abdominal burning pain

Acute diarrhea

Agent: bacteria


Symptoms: frequent loose or liquid bowel movements

Salmonellosis

Agent: bacteria, salmonella


Gr negative


Bacteria invade the intestinal mucous membrane



Typhoid fever

Agent: salmonella typhi


Symptoms: Headache, high fever and diarrhea (after 2nd week)


Vaccine available


Treatment: antimicrobial drugs

E. Coli 0157:H7

Agent: bacteria, e. coli


Symptoms: Gastroenteritis, bloody diarrhea, anemia, kidney damage, blindness, seizure and stroke


Transmission: ingestion of contaminated and undercooked beef, lettuce, and veggies


Treatment: supportive therapy

Cholera

Agent: bacteria, vibrio cholerae


Symptoms: Severe diarrhea with sudden loss of fluids, shock collapse, and even deathThe blood becomes very viscous


Treatment: replace lost fluids, electrolytes, tetracycline

Staphilococcal food poisoning

Agent: Bacteria, staphylococcus aureus


Symptoms: Abdominal cramps, vomiting and diarrhea,self-limiting, recovery within 24 hours

Cryptosporidiosis

Agent: protozoan, cryptosporidium hominis


Symptom: diarrhea

Giardiasis

Agent: protozoan, giardia lamblia


Infection via contaminated water


Symptoms:Nausea, intestinal gas, weakness, abdominal cramps, diarrhea


Treatment: metronidazole

Hepatitis

Virus (HEP A, B, C, D, E)


Hepatitis is an inflammation of the liver.


Symptoms: Jaundice, abdominal pain, fatigue, nausea, vomiting, appetite loss

Hepatitis A

Agent: single stranded RNA virus, no envelope


Symptoms: Infection is acquired via oral rout ( fecal contamination of food, water, and oysters) Symptoms: anorexia, nausea, fever, abdominal discomfort, fever, and chills and jaundice


Vaccine available

Hep B

Agent: double stranded DNA virus with the envelope


Transmission: break in the skin-body fluids (blood, saliva, breast milk, semen)


Symptoms: loss of appetite, fever, joint pains, jaundice

Cystitis

Agent: Bacteria, E. Coli, Klebsiella, Proteus, and pseudomonads


Females more susceptible-due to short urethra that is close to the anus


Symptoms: frequent, urgent and painful urination, urine may be cloudy


Treatment: antimicrobial drugs

Pyelonephritis

Agent: bacteria, E. coli


Symptoms: inflammation of kidneys, back pain


Treatment: intravenous antibiotics

Leptospirosis

Agent: bacteria: leptospira interrogans


Humans contract the disease via urine-contaminated water


Symptoms: 1st episode :headache, muscular ache, chill.2nd episode: kidney failure


Treatment: antibiotic treatment in later stage not effective

Gonorrhea

Agent: bacteria, Neisseria gonorrhea


Symptoms in males: Painful urination and discharge of pus.


Symptoms in females: females are asymptomatic (no symptoms), in most cases.


Treatment: PCN, Ciprofloxacin, cephalosporins

Pelvic Inflammatory Disease (PID) women only

Agent: bacteria, Neisseria gonorrhea, chlamydia trachomatis, mycoplasma hominis (rarely)


Symptoms: inflammation of uterine tubes, fever, abdominal pain


Treatment: cephalosporin

Syphilis

Agent: bacteria, treponema pallidum


Treatment: benzathin, PCN

Primary stage syphilis
soft chancre- small lesions on the skin in the site of infection
Secondary Stage Syphilis
Several weeks after the primary stage-skin rashes and lesion (contain bacteria), infection by non-sexual contact is possible
Tertiary Stage syphilis
lesions called gummas (rubbery thickening of the skin or internal organs) not very infectious. Organs affected: cardiovascular system, and brain resulting in personalty change, blindness, and seizure
Chlamydial infection

Agent: bacteria


Symptoms in women: the bacteria initially infect the cervix and urethra, might have an abnormal vaginal discharge or a burning sensation when urinating.


Symptoms in men: discharge from the penis or a burning sensation when urinating

Lymphogranuloma venereum

Agent: bacteria, chlamydia trichomatis


Symptoms: Small painless ulcer on genitalia , swelling and redness of the skin the groin area,swollen groin lymph nodes on one or both sides

Genital herpes

Virus, HSV2


Symptoms: Vesicles appear on the skin of genital organs, painful urination. Vesicles disappear in 2 weeks


Treatment: acyclovir, valacyclovir

Trichomoniasis

Agent: protozoan, Trichomonas vaginalis


Inhabitant of vagina and urethra in males Males have no symptoms of infection.


Symptoms in females: irritation and itching with the discharge


Treatment: metranidazol-administered to both partners