Microbio Ch. 4 Pathogenic Dna Viruses

Front 1

List five families of double-stranded DNA viruses.

Back 1

Poxviridae, Herpesviridae, Papillomaviridae, Polyomaviridae and Adenoviroidae.

Hint 1

PHPPA

Front 2

List the family of single-stranded DNA Viruses.

Back 2

Parvoviridae

Front 3

List the family with both dsDNA and ssDNA.

Back 3

Hepadnaviridae

Front 4

Poxviridae is a double-stranded DNA virus containing what?

Back 4

complex capsids and lipid envelopes

Hint 4

It is the outer shell of a virus. It consists of several monomeric subunits made of protein. The purpose is to protect the genetic material of the virus, determine if a cell is suitable for infection, starts the actual infection by attaching and "opening" the target cell and injecting the genetic material of the virus into the cell.

They cover their protein coats. They help viruses enter host cells. They serve to identify and bind to receptor sites on the host's membrane and thenn fuses with the host's membrane, allowing the itself to enter and infect the host.

Front 5

Poxviridae are the largest diameter viruses. True or false?

Back 5

True.

Front 6

What does the Poxviridae virus infect?

Back 6

Different mammals but usually species specific.

Front 7

Why doesn't Poxviridae viruses hardly infect humans and how can infection occur?

Back 7

Most do not infect humans because they cannot attach to human cells. Infection occurs primarily by inhalation of viruses from respiratory droplets or skin lesions, but can also accur by skin inoculation. Close contact is necessary for infection to occur.

Front 8

List the two main human poxvirus diseases.

Back 8

Smallpox and molluscum contagiosum.

Hint 8

One them is life-threatening and infect only humans.

Front 9

Poxvirus diseases causes what problem to the body?

Back 9

Skin lesions.

Front 10

Smallpox is also known as what?

Back 10

Variola.

Hint 10

Has two forms, major which causes facial disfiguration and minor which is less severe with a lower mortality rate.

Front 11

Exposing a human to vaccinia (cowpox) virus prevented small pox. True or false?

Back 11

True.

Front 12

New World 1500 brought smallpox. True or false?

Back 12

False, the Spanish conquistadors did to the New World around 1500.

Front 13

How is smallpox acquired?

Back 13

By inhalation of smallpox viruses in respiratory secretions or skin lesions.

Front 14

In order for a natural infection of smallpox virus to occur, what must be considered?

Back 14

Close contact with an infected host.

Front 15

The smallpox virus to skin where it produces the characteristic pox lesion is caused by?

Back 15

Viremia.

Front 16

What does viremia?

Back 16

Viruses in the bloodstream.

Front 17

Smallpox is diagnosed by what two characteristics?

Back 17

High fever and pox lesions.

Front 18

How do the pox lesions develop on the body?

Back 18

All over the body at the same time, same development stage at the same time, giving them a similar size and appearance.

Front 19

There is no treatment for smallpox. T/F?

Back 19

T.

Front 20

Molluscum Contagiosum is a disease from what family of pathogenic DNA viruses?

Back 20

Poxviridae/poxviruses

Front 21

Smallpox is a disease from what family of pathogenic DNA viruses?

Back 21

Poxviridae/poxviruses.

Front 22

What are other poxviruses that can infect humans?

Back 22

Orf (sheep-goat pox), cowpox and monkeypox.

Front 23

Herpesviridae has how many strands of DNA?

Back 23

dsDNA.

Front 24

How does Herpesviridae enter the cell?

Back 24

Attach to a host cell receptor and enter the cell through the fusion of their lipid envelope with the cell membrane.

Front 25

Herpesviridae's genera, Simplexviruses is also known as what?

Back 25

Herpes simplex virus/HSV.

Front 26

Fluid from genital herpes vesciles contain what?

Back 26

Many virions.

Front 27

How is genital herpes transmitted?

Back 27

By contact with besicle fluid or secretions containing HSV

Front 28

Varicella-Zoster virus is in what genus?

Back 28

Varicellovirus.

Front 29

Varicellovirus is in what genera?

Back 29

Herpesviridae.

Front 30

Varicella-Zoster virus is also known as?

Back 30

VZV/human herpes virus 3 (HHV 3)

Front 31

Varicella-Zoster virus (VZV) causes what two diseases?

Back 31

Varicella and Herpes zoster.

Front 32

Varicella is commonly called what?

Back 32

Chicken pox.

Front 33

Herpes zoster is commonly called what?

Back 33

Shingles.

Front 34

Epstein-Barr virus is in what genus?

Back 34

Lympohocrytovirus.

Front 35

Epstein-Barr virus is a with the genera of what?

Back 35

Herpesviridae.

Front 36

EBV enters the the bloodstream and invades what?

Back 36

B lymphocytes.

Front 37

When EBV invades B lymphocytes, they supress what function for cells?

Back 37

Supresses apoptosis.

Front 38

What kills infected by EBV B lymphocytes?

Back 38

Cytotoxic T cells.

Front 39

Cytomegalovirus is part of what genera?

Back 39

Herpesviridae.

Front 40

Cytomegalovirus causes infected cells to enlarge and develop inclusion bodies. T/F?

Back 40

True.

Front 41

Papillomavirus is a pathogenic DNA virus with how many DNA strands?

Back 41

dsDNA.

Front 42

What does the papillomavirus cause?

Back 42

Papillomas, commony known as warts.

Front 43

How does papillomas transmitted?

Back 43

Direct contact and fomites.

Front 44

What are the two types of genital warts that cause cancer of the cervix?

Back 44

Genital warts 16 & 18.