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44 Cards in this Set

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List five families of double-stranded DNA viruses.
Poxviridae, Herpesviridae, Papillomaviridae, Polyomaviridae and Adenoviroidae.
PHPPA
List the family of single-stranded DNA Viruses.
Parvoviridae
List the family with both dsDNA and ssDNA.
Hepadnaviridae
Poxviridae is a double-stranded DNA virus containing what?
complex capsids and lipid envelopes
It is the outer shell of a virus. It consists of several monomeric subunits made of protein. The purpose is to protect the genetic material of the virus, determine if a cell is suitable for infection, starts the actual infection by attaching and "opening" the target cell and injecting the genetic material of the virus into the cell.

They cover their protein coats. They help viruses enter host cells. They serve to identify and bind to receptor sites on the host's membrane and thenn fuses with the host's membrane, allowing the itself to enter and infect the host.
Poxviridae are the largest diameter viruses. True or false?
True.
What does the Poxviridae virus infect?
Different mammals but usually species specific.
Why doesn't Poxviridae viruses hardly infect humans and how can infection occur?
Most do not infect humans because they cannot attach to human cells. Infection occurs primarily by inhalation of viruses from respiratory droplets or skin lesions, but can also accur by skin inoculation. Close contact is necessary for infection to occur.
List the two main human poxvirus diseases.
Smallpox and molluscum contagiosum.
One them is life-threatening and infect only humans.
Poxvirus diseases causes what problem to the body?
Skin lesions.
Smallpox is also known as what?
Variola.
Has two forms, major which causes facial disfiguration and minor which is less severe with a lower mortality rate.
Exposing a human to vaccinia (cowpox) virus prevented small pox. True or false?
True.
New World 1500 brought smallpox. True or false?
False, the Spanish conquistadors did to the New World around 1500.
How is smallpox acquired?
By inhalation of smallpox viruses in respiratory secretions or skin lesions.
In order for a natural infection of smallpox virus to occur, what must be considered?
Close contact with an infected host.
The smallpox virus to skin where it produces the characteristic pox lesion is caused by?
Viremia.
What does viremia?
Viruses in the bloodstream.
Smallpox is diagnosed by what two characteristics?
High fever and pox lesions.
How do the pox lesions develop on the body?
All over the body at the same time, same development stage at the same time, giving them a similar size and appearance.
There is no treatment for smallpox. T/F?
T.
Molluscum Contagiosum is a disease from what family of pathogenic DNA viruses?
Poxviridae/poxviruses
Smallpox is a disease from what family of pathogenic DNA viruses?
Poxviridae/poxviruses.
What are other poxviruses that can infect humans?
Orf (sheep-goat pox), cowpox and monkeypox.
Herpesviridae has how many strands of DNA?
dsDNA.
How does Herpesviridae enter the cell?
Attach to a host cell receptor and enter the cell through the fusion of their lipid envelope with the cell membrane.
Herpesviridae's genera, Simplexviruses is also known as what?
Herpes simplex virus/HSV.
Fluid from genital herpes vesciles contain what?
Many virions.
How is genital herpes transmitted?
By contact with besicle fluid or secretions containing HSV
Varicella-Zoster virus is in what genus?
Varicellovirus.
Varicellovirus is in what genera?
Herpesviridae.
Varicella-Zoster virus is also known as?
VZV/human herpes virus 3 (HHV 3)
Varicella-Zoster virus (VZV) causes what two diseases?
Varicella and Herpes zoster.
Varicella is commonly called what?
Chicken pox.
Herpes zoster is commonly called what?
Shingles.
Epstein-Barr virus is in what genus?
Lympohocrytovirus.
Epstein-Barr virus is a with the genera of what?
Herpesviridae.
EBV enters the the bloodstream and invades what?
B lymphocytes.
When EBV invades B lymphocytes, they supress what function for cells?
Supresses apoptosis.
What kills infected by EBV B lymphocytes?
Cytotoxic T cells.
Cytomegalovirus is part of what genera?
Herpesviridae.
Cytomegalovirus causes infected cells to enlarge and develop inclusion bodies. T/F?
True.
Papillomavirus is a pathogenic DNA virus with how many DNA strands?
dsDNA.
What does the papillomavirus cause?
Papillomas, commony known as warts.
How does papillomas transmitted?
Direct contact and fomites.
What are the two types of genital warts that cause cancer of the cervix?
Genital warts 16 & 18.