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15 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Antibody-Mediated Autoimmunity has the same mechanism as what hypersensitivity?
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Type II Hypersensitivity
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Immune complex mediated autoimmunity has the same mechanism as what hypersensitivity?
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Type III Hypersensitivity
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T-Cell Mediated Autoimmunity has the same mechanism as what hypersensitivity?
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Type IV Hypersensitivity (DTH)
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classify:
Autoimmune hemolytic anemia |
antibody mediated autoimmunity
-RBC's cleared by? |
-MAC attack by compliment
-cleared by spleen -ADCC |
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classify:
Autoimmune Thrombocytopenia |
antibody mediated autoimmunity
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classify:
Goodpasture's syndrome |
antibody mediated autoimmunity
IgG's bind to? which leads to? |
Type IV collagen --> inflammatory response in kidneys
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which autoimmune diseases have autoantibodies against cell surface receptors?
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Graves Disease, Myasthenia Gravis, and Type 2 Diabetes
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Classify:
Graves Disease |
antibody mediated autoimmunity
(Hyperthyroidism) Ab's bind to? |
TSH receptor on thyroid
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Classify:
Myasthenia Gravis |
antibody mediated autoimmunity
Ab's to? which leads to? |
AChR on muscle cells --> endocytosis --> muscle weakening
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Classify:
Insulin-resistant Diabetes |
antibody mediated autoimmunity
Ab to? Which leads to? |
insulin receptor
...if inhibitor --> hyperglycemia ...if agonist --> hypoglycemia |
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Classify:
Hashimoto's Disease |
antibody mediated autoimmunity
(hypothyroidism) Ab's to? |
Thyroid gland
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Classify:
Systemic Lupus Erythematosus |
Immune-Complex Mediated Autoimmunity
Ab's to? which leads to? |
DNA and aspects of Nucleosome
glomerulonephritis, vasculitis, arthritis, butterfly rash, fatigue, headaches |
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Classify:
Insulin-dependent Diabetes |
T-cell Mediated Autoimmunity
(Type 1/ Juvenile Diabetes) Ab's to? |
Pancreatic Beta cells
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Classify:
Rheumatoid Arthritis (RA) |
T-cell Mediated Autoimmunity
Ab to? Other substances present? |
to synovial joint Ag
RF - IgM/G/A to Fc region of IgG |
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Classify:
Multiple Sclerosis (MS) |
T-cell Mediated Autoimmunity
Ab to? mechanism? |
Myelin Basic Protein
activated CD4+Tcells secrete IFN gamma activating MO --> plaques |
