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50 Cards in this Set

  • Front
  • Back
What are the three classes of superficial mycoses?
superficial (confined to keratinaceous stratum corneum)
cutaneous (top layers of skin, hair, nails)
subcutaneous (deeper levels of skin)
What immediately differentiates fungi from plants?
no chlorophyll/photosynthetic pigments.

cell wall present
What differentiates fungal from mammalian plasma membranes?
ergosterols rather than cholesterols embedded in membrane.
What is the difference between yeasts and molds?
Yeasts = single discrete cells, reproduce by budding/fission

Molds = grow as mycelium (mass of hyphae), apical growth, conidia, sporangiophores
What are the asexual and sexual propagules of phylum Ascomycota?
sexual: ascospores, >2 spores encased in saclike ascus

asexual: conidia
What are the asexual and sexual propagules of phylum Basidiomycota?
sexual: basidiospores, attached to projection called a basidium.

asexual: conidia
What are the asexual and sexual propagules of phylum Zygomycota?
sexual: zygospores, spiky looking

asexual: sporangiospores ( = conidia)
Teleomorph = ?
sexually reproducing form of fungal spp.
Anamorph = ?
asexually reproducing form of fungal spp.
Phialide = ?
Vial-shaped cell attached to conidiophores that extrude conidia in chains.
Conidia = ?
Asexual reproductive structure of mold form of fungus. Produced via mitosis.
Phialoconidia = ?
Conidia produced/extruded by phialides.
What does the greek root -phore mean?
"bearer of ____"

conidioPHORE = conidia bearer
basidiophore = basidium bearer
Ascus = ?
saclike structure that encloses ascospores.
Dematiaceous = ?
describes "darkly pigmented" fungi, usually dark brown or black.
Sporangium = ?
thin-walled sac in which asexual spores develop.

Only in Zygomycetes.
Sporangiophore = ?
differentiated hypha bearing a sporangium.
Conidiophore = ?
Differentiated hypha upon which conidia develop.
Annellide = ?
Similar to phialide; produces conidia that leave ring-like scars when they detach.

phialides don't get scars.
What is the purpose of lactophenol blue in fungal wet mounts?
Phenol to kill fungus and denature enzymes (prevent cell lysis)

Cotton Blue dye to stain chitin in fungus cell wall
What are the distinguishing characteristics of genus Alternaria?
Ascomycete

hyphae composed of club-shaped, dematiaceous macroconidia like teardrops linked together.

poroconidia extruded through pores in hyphae
What are the distinguishing characteristics of genus Aspergillus?
ascomycete

swollen bulbous conidiophores with phialides arranged dandelion-fashion, bearing chains of conidia.
What are the distinguishing characteristics of genus Rhizopus?
Zygomycete

sporangiophores bear large swollen sporangium containing sporangiospores. rootlike rhizoids on opposite end of sporangiophore-bearing hyphae.
What are the distinguishing characteristics of genus Penicillium?
ascomycete

conidiophore is long and slender, has phialides that make chains of conidia. paintbrush/hand looking thing
What are the distinguishing characteristics of genus Mucor?
zygomycete

thick hyphae w/no septa; large bulbous sporangia but no rhizoids on opposite end of sporangiophore-bearing hyphae.
What are the distinguishing characteristics of genus Scopulariopsis?
ascomycete

stubby short conidiophores that have annellides (not phialides). large conidia w/dark center and clear looking capsule structure.
What is the differenece between infection and colonization?
infection = organism present and causing disease

colonization = organism present as harmless commensal
Pityriasis Versicolor
Superficial mycosis; harmless/painless

skin discoloration and scaling

aka tinea versicolor.

caused by Malassezia furfur.
Seborrheic Dermatitis
aka dandruff. caused by Malassezia furfur.
Follicular pityriasis
fungal infection of hair follicles by Malassezia furfur
Malassezia furfur
lipophilic yeast, likes sebum and cooler temps --> grows on skin surface.

basidiomycete

causes pityriasis versicolor, seborrheic dermatitis, follicular pityriasis
Tinea Nigra
superficial patches of dark pigmentation in palms/soles of feet

Exophialia werneckii (mold form is etiologic agent)

tropical areas, females
Tinea pedis
Trichophyton mentagrophytes (asco)

athlete's foot, transmitted thru contact w/contaminated skin flakes--shower rooms, etc.

on webs and soles of feet: itching, scaling, cracking, inflammation, maceration (liquification)
Tinea capitis
infection of hair by Trichophyton tonsurans

grey, matted hair, UV fluorescence; transmitted thru contact (barber shops)

black males, economically disadvantaged areas
Black piedra
Piedraia hortae, septate mold

waxy black nodules on scalp hairs esp. in males and swimmers
White piedra
Trichosporon biegelii (ascomycete)

white nodules on hair in genital area, beards, mustaches.

tropical areas, males
What are the unifying characteristics of the dermatophytes?
-ascomycetes
-grow as septate molds
-incidence of infection increases w/age
Tinea cruris
"jock itch"

itching, burning, inflammation

dermatophyte
Onychomycosis/Tinea unguium
fugal nail infections by dermatophytes and nondermatophytes

nails deform, change color/consistency
Chromoblastomycosis
unbudded, pigmented yeasts embedded in skin

etiologic agent = dematiaceous yeasts

males, tropical areas, exposure to soil
Phaeohyphomycosis
etiologic agent = proliferating HYPHAE (not yeasts) in tissue. like chromoblasto but with molds not yeasts.

Scedosporium prolificans

no gender bias, tropics, exposure to soil, wood splinters, etc.
What test result differentiates between Trichophyton mentagrophytes and T. rubrum?
hair perforation.

T. mentagrophytes perforates hair
T. rubrum does not.
What test result differentiates Trichophyton tonsurans from other Trichophyton species?
Thiamine-enhanced growth.

Thiamine supplementation enhances growth of T. tonsurans but not other species.
What structural difference separates Trichophyton mentagrophytes from other Trichophyton species?
coiled hyphae
Which fungi have spores and which fungi have conidia?
Zygomycetes have spores

Ascomycetes, Basidiomycetes have conidia.

same thing but different name
What is the microscope pointer width at 10X?
25 um
What is the microscope pointer width at 40X?
6 um
What is the microscope pointer width at 100X?
2.5 um
What is the structural trademark of Sporothrix?
conidia arranged in "flowerettes"

capsulated cigar-shaped yeast cells in vivo
What is the structural growth pattern of most dimorphic fungi?
Hyphae in nature

Yeast in vivo (tissue)