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19 Cards in this Set
- Front
- Back
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Causative organism
Erlichiosis |
Ehrlichia chaffeensis
Gram negative Coccobaccilus Cholesterol in membrane No LPS |
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Causative organism
Anaplasmosis |
Anaplasma phagocytophilum
Gram negative coccobaccillus Cholesterol in membrane No LPS |
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Causative organism
Q fever |
Coxiella burnetii
Gram negative Bacillus Weak LPS activity, phase antigenic variation(Phase I and II) |
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Geographic Location
Ehrlichiosis |
Worldwide
SE and MW states in the US |
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Geographic Location
Anaplasmosis |
Worldwide
MW and NE states in the US |
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Geographic Location
Q fever |
Worldwide
Rare in the US |
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Principle Reservoir
Erlichiosis |
Horses
Deer Dogs Ticks |
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Principle Reservoir
Anaplasmosis |
Various small animals
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Principle Reservoir
Q fever |
Many animals
Birds Ticks |
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Principle vector
Erlichiosis |
Lone star tick
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Principle vector
Anaplasmosis |
Black legged ticks
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Principle vector
Q fever |
Humans: No vector
Inhalation most common mode of transmission |
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Clinical Manifestarions
Erlichiosis |
1) Infects monocytes/macrophages;
2) Nonspecific symptoms 3) Rash present in ~20% of pts |
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Clinical Manifestarions
Anaplasmosis |
1) Infects neutrophils;
2) Similar symptoms as erlichiosis; 3) Rash presents in ~10% of pts |
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Clinical Manifestarions
Q fever |
1) Initial proliferation in lung macrophages.
2) Acute: Asymptomatic or mild - can mimic atypical pneumonia and cause hepatitis 3) Chronic: subacute endocarditis |
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Mortality rates
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Erlichiosis: 2-3%
Anaplasmosis: <1% Q fever: Acute: ~1% Chronic: ~65% |
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Treatment
Erlichiosis |
Doxycyline- initiate treatment upon suspicion
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Treatment
Anaplasmosis |
Doxycyline- initiate treatment upon suspicion
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Treatment
Q fever |
Acute: Doxycycline
Chronic: Combination Therapy |
