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67 Cards in this Set
- Front
- Back
Hair in nostrils traps large particles called:
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Vibrissae
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Mucous glands secrete:
Serous glands secrete: Natural antibiotic in mucous: |
Mucous
watery lysozyme and kills bacteria Defensins |
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Cause of strep throat:
Gram ____ cocci Hemolytic_________ |
Streptococcus pyogenes
cocci positive Beta |
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Spread by :
Incubation period: |
Droplet, food
2-5 days |
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Symptoms:
Can lead to this? |
Severe sore throat, painful swallowing, fever >101, swollen tonsils, white or yellow spots.
Scarlet fever |
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What are symptoms of above disease:
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Fever >101, Body rash, Strawberry rash on tongue.
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Streptococcus in wounds can lead to:
Caused by: |
Necrotis fascitis
Exotoxins |
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Dx of streptococcus pyogenes:
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Rapid test-Antigen
Throat culture Even if rapid test neg still have to culture. NOT BY GRAM STAIN |
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No sensitivity test needed responds well to:
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PCN
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Do not use this for dx:
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Gram stain
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Diptheria is caused by what:
Exotoxin causes what symptoms: |
Corynebacterium diptheriae
Fever, swelling of lymph nodes, dysphagia, leathery patches on tonsils. |
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What type is it gram__?
Characteristics: |
Gram positive rod
Non-motile,AEROBIC, CLUB shaped. |
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Found in ______?
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Upper Resp tract, low fever, pseudo membrane, can lead to resp distress.
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Diagnosed by?
What media? |
Pseudomembrane, neck swellinjg, throat culture.
GRAM STAIN very important with this bacteria... |
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Treatment:
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Immediate- very slow recovery. Diptheria anti-toxin and PCN
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Commom cold is found in ___
Caused by: |
URT
RNA ,Rhinovirus |
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Transmitted by:
Incubation: |
Aerosols, formites,most common route is the nose.
5-7 days |
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Symptoms of the cold that differ from flu:
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Cold has runny nose and sneezing, flu does not.
Common symptoms are low grade fever, sore throat,slight fever and runny nose. |
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Treatment:
Dx: |
None, unless severe. Asprin if febrile.
Clinical presentation or May dx with cell cultures on live cells if severe enough. |
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Rhinovirus is RNA or DNA based?
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RNA
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Adenovirus is DNA or RNA based?
First found on what? % re-infection rate? |
DNA.
Adenoid tissue. 50% |
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Transmitted by:
Mostly found in URI but can lead to: |
Direct,fecal-oral, waterborne, not normally airborne.
GI tract where it cannot be killed. |
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Incubation:
Symptoms: |
2-14 days.
Appear as cold, croup or bronchitis, LASTS 3-5 days. |
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Treatment:
Dx: |
None.
Nasal swabs or washings,RT-PCR, cell culture looking for cytopathic effect- if postitive then have adenovirus |
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Pneumonia s/s:
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inflammation of alveoli, chest pain when coughing, hemopytis,n/v,muscle soreness, headache. POOR GAS EXCHANGE
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Most common cause of bacterial pneumonia:
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Streptococcus pneumoniae
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Characteristics of strep pneumoniae?
1/3 cause of all community acquired pneumonia |
Gram positive lancet shaped rod, normal flora that causes infection, ALPHA HEMOLYTIC, AEROTOLERANT
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Streptococcus pneumoniae is divided in to two forms:
Effects young adults: Infant, young children and elderly: |
LOBAR
BRONCHIAL |
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Incubation:
S/S: |
1-3 days
Fever, chills, HA,Cough, chest pain, disorientation,sob |
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DX;
If positive for this form it will have a positive zomne of inhibition. If negative -No zone. |
Sputum and resp culture.
Gram stain, hemolysis, and special Optichin- Optichin is antibiotic that is sensitive to this form of pneumonia. |
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Tx for streptococci pneumoniae:
Loves Heme factors: |
Universally responds to PCN, takes 24-48 hours.
X and V factors X= heme V= NAD factor |
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This is a gram negative rod, that is non-motile and loves heme:
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Hemophilus influenza
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Naturally acquired disease, found in infants and small children, may be seen in adults, bacterial form of influenza.
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Hemophilus influenza
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Resp culture uses this every time:
To test for this influenze use: Main method: |
Chocolate plate
Chocolate plate and quad plate. Quad plate. |
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X and V are not :
Diagnosis: TX: |
Hemolytic
Resp culture, PCR, Blood culture 3rd generation Cephalosporins |
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Hemophilus influenzae s/s:
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Upper resp tract, nasopharyngitis, sinusits-otitis. Can lead to bacteremia. and painful joints or meningitis.
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Whooping cough is caused:
Is gram ___ Found in _________ |
Bordetella pertussis-
Gram negative coccobacillus Resp tract |
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vaccination is:
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PTX (pertussis toxin)
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Whooping cough is a gram _____?
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Negative coccobacillis
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Sputum culture versus saliva can tell by:
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Saliva has epithelial cells and sputum does not.
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Whooping cough is highly:
Direct contact: Still contagious after: |
Communicable and contagious.
Nasal,oral, and resp secretions. 3 weeks. |
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Incubagtion period:
3 distinct stages: |
1-2 weeks
Catarrhal- last 1-2 weeks Paroxymal -last 2-3 weeks Convalescent- last 3-16 weeks |
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In catarrhal stage symptoms:
In paroxymal stage: |
mild cough, fever, runny nose
Paroxyms - burst of coughing-whooping- with gasping for air. |
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Convalescent stage:
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Cough slowly decreases over 3-16 weeks.
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Complications of whooping cough:
Infants under age are at risk: |
Death related to bacterial pneumonia, ear infections,seizures, loss of appetite, dehydration,wt loss and hypoxia.
less than six months |
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Diagnosis:
PCR looks at: ELISA looks at: |
( also presumptive on symptoms)Nasopharyngeal aspirate or nasal swab
Bordet-Gengou potato glycerol agar. PCR looks for DNA ELISA looks at antigen |
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TX for Whooping cough:
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Erythromycin
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Prevention:
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Vaccination
DPat- children Tdap- adults every 10 years. |
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Whooping cough is still contagious after:
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3 weeks
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Humans are the sole:
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resvoir for whooping cough
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TB is caused by:
ACID fast: |
Mycobacterium tuberculosis
Rod |
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Characteristics:
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aerobic, slow grower, mycolic acid wax found in cell wall
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Symptoms of TB:
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Chest pain, weight loss, night sweats, coughing up blood and sputum, no appetite, weakness or fatigue.
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Classic TB sign:
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Bad cough greater than 3 weeks.
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DX by:
Flourescense stain is just a _ Definitive dx is done by: |
Sputum or tissue culture. Bronchial washings/lung tissue. ACID FAST STAIN
SCREEN State lab. |
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DRUGS for TB:
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Triple therapy. 4 main drugs.
Isoniazid, Rifampin, Ethambutol,Pyrazinamide. |
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Screened with :
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PPD test. SQ. Wheal formation. Induration size. 5-10-15
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Small changes to antigens with time:
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Antigenic shift
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Large changes that completely alter antigen appearance:
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Antogenic drift- large changes with Swine influenze novus and H1N1 Novus antigenic DRIFT.
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Influenza is ___ based.
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RNA virus
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Two types of Influenza:
Human strains are: Avian strains: |
Type A and B
H1 and H3 and rare H9 H5, H7 |
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Type B is human and has 2 strains:
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Shanghai and Malaysia
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S/S of influenza:
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High fever, headache and severe fatigue, dry cough,sore throat, stuffy nose, body aches and n/v/d.
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Diagnosis:
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Rapid flu test-
PCR- is very specific and few places of subtypes. |
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catches most positive cases, n
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High sensitivity 70%
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not many false positives,
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high specificity 90%
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Influenza treatment:
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Tamiflu (which is becoming resistant)
Relenza |