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67 Cards in this Set

  • Front
  • Back
Hair in nostrils traps large particles called:
Vibrissae
Mucous glands secrete:

Serous glands secrete:
Natural antibiotic in mucous:
Mucous

watery lysozyme and kills bacteria
Defensins
Cause of strep throat:

Gram ____ cocci

Hemolytic_________
Streptococcus pyogenes
cocci positive
Beta
Spread by :

Incubation period:
Droplet, food

2-5 days
Symptoms:

Can lead to this?
Severe sore throat, painful swallowing, fever >101, swollen tonsils, white or yellow spots.
Scarlet fever
What are symptoms of above disease:
Fever >101, Body rash, Strawberry rash on tongue.
Streptococcus in wounds can lead to:
Caused by:
Necrotis fascitis

Exotoxins
Dx of streptococcus pyogenes:
Rapid test-Antigen
Throat culture
Even if rapid test neg still have to culture.
NOT BY GRAM STAIN
No sensitivity test needed responds well to:
PCN
Do not use this for dx:
Gram stain
Diptheria is caused by what:

Exotoxin causes what symptoms:
Corynebacterium diptheriae

Fever, swelling of lymph nodes, dysphagia, leathery patches on tonsils.
What type is it gram__?
Characteristics:
Gram positive rod
Non-motile,AEROBIC, CLUB shaped.
Found in ______?
Upper Resp tract, low fever, pseudo membrane, can lead to resp distress.
Diagnosed by?

What media?
Pseudomembrane, neck swellinjg, throat culture.
GRAM STAIN very important with this bacteria...
Treatment:
Immediate- very slow recovery. Diptheria anti-toxin and PCN
Commom cold is found in ___

Caused by:
URT
RNA ,Rhinovirus
Transmitted by:

Incubation:
Aerosols, formites,most common route is the nose.

5-7 days
Symptoms of the cold that differ from flu:
Cold has runny nose and sneezing, flu does not.
Common symptoms are low grade fever, sore throat,slight fever and runny nose.
Treatment:

Dx:
None, unless severe. Asprin if febrile.
Clinical presentation or May dx with cell cultures on live cells if severe enough.
Rhinovirus is RNA or DNA based?
RNA
Adenovirus is DNA or RNA based?
First found on what?

% re-infection rate?
DNA.

Adenoid tissue.
50%
Transmitted by:
Mostly found in URI but can lead to:
Direct,fecal-oral, waterborne, not normally airborne.

GI tract where it cannot be killed.
Incubation:

Symptoms:
2-14 days.

Appear as cold, croup or bronchitis, LASTS 3-5 days.
Treatment:

Dx:
None.

Nasal swabs or washings,RT-PCR, cell culture looking for cytopathic effect- if postitive then have adenovirus
Pneumonia s/s:
inflammation of alveoli, chest pain when coughing, hemopytis,n/v,muscle soreness, headache. POOR GAS EXCHANGE
Most common cause of bacterial pneumonia:
Streptococcus pneumoniae
Characteristics of strep pneumoniae?

1/3 cause of all community acquired pneumonia
Gram positive lancet shaped rod, normal flora that causes infection, ALPHA HEMOLYTIC, AEROTOLERANT
Streptococcus pneumoniae is divided in to two forms:
Effects young adults:
Infant, young children and elderly:
LOBAR

BRONCHIAL
Incubation:

S/S:
1-3 days

Fever, chills, HA,Cough, chest pain, disorientation,sob
DX;

If positive for this form it will have a positive zomne of inhibition. If negative -No zone.
Sputum and resp culture.
Gram stain, hemolysis, and special Optichin- Optichin is antibiotic that is sensitive to this form of pneumonia.
Tx for streptococci pneumoniae:

Loves Heme factors:
Universally responds to PCN, takes 24-48 hours.

X and V factors
X= heme
V= NAD factor
This is a gram negative rod, that is non-motile and loves heme:
Hemophilus influenza
Naturally acquired disease, found in infants and small children, may be seen in adults, bacterial form of influenza.
Hemophilus influenza
Resp culture uses this every time:

To test for this influenze use:
Main method:
Chocolate plate

Chocolate plate and quad plate.
Quad plate.
X and V are not :

Diagnosis:

TX:
Hemolytic

Resp culture, PCR, Blood culture
3rd generation Cephalosporins
Hemophilus influenzae s/s:
Upper resp tract, nasopharyngitis, sinusits-otitis. Can lead to bacteremia. and painful joints or meningitis.
Whooping cough is caused:
Is gram ___

Found in _________
Bordetella pertussis-
Gram negative coccobacillus

Resp tract
vaccination is:
PTX (pertussis toxin)
Whooping cough is a gram _____?
Negative coccobacillis
Sputum culture versus saliva can tell by:
Saliva has epithelial cells and sputum does not.
Whooping cough is highly:

Direct contact:
Still contagious after:
Communicable and contagious.
Nasal,oral, and resp secretions.
3 weeks.
Incubagtion period:

3 distinct stages:
1-2 weeks

Catarrhal- last 1-2 weeks
Paroxymal -last 2-3 weeks
Convalescent- last 3-16 weeks
In catarrhal stage symptoms:

In paroxymal stage:
mild cough, fever, runny nose

Paroxyms - burst of coughing-whooping- with gasping for air.
Convalescent stage:
Cough slowly decreases over 3-16 weeks.
Complications of whooping cough:

Infants under age are at risk:
Death related to bacterial pneumonia, ear infections,seizures, loss of appetite, dehydration,wt loss and hypoxia.
less than six months
Diagnosis:

PCR looks at:
ELISA looks at:
( also presumptive on symptoms)Nasopharyngeal aspirate or nasal swab
Bordet-Gengou potato glycerol agar. PCR looks for DNA
ELISA looks at antigen
TX for Whooping cough:
Erythromycin
Prevention:
Vaccination
DPat- children
Tdap- adults every 10 years.
Whooping cough is still contagious after:
3 weeks
Humans are the sole:
resvoir for whooping cough
TB is caused by:
ACID fast:
Mycobacterium tuberculosis

Rod
Characteristics:
aerobic, slow grower, mycolic acid wax found in cell wall
Symptoms of TB:
Chest pain, weight loss, night sweats, coughing up blood and sputum, no appetite, weakness or fatigue.
Classic TB sign:
Bad cough greater than 3 weeks.
DX by:
Flourescense stain is just a _

Definitive dx is done by:
Sputum or tissue culture. Bronchial washings/lung tissue. ACID FAST STAIN
SCREEN
State lab.
DRUGS for TB:
Triple therapy. 4 main drugs.
Isoniazid, Rifampin, Ethambutol,Pyrazinamide.
Screened with :
PPD test. SQ. Wheal formation. Induration size. 5-10-15
Small changes to antigens with time:
Antigenic shift
Large changes that completely alter antigen appearance:
Antogenic drift- large changes with Swine influenze novus and H1N1 Novus antigenic DRIFT.
Influenza is ___ based.
RNA virus
Two types of Influenza:
Human strains are:
Avian strains:
Type A and B
H1 and H3 and rare H9
H5, H7
Type B is human and has 2 strains:
Shanghai and Malaysia
S/S of influenza:
High fever, headache and severe fatigue, dry cough,sore throat, stuffy nose, body aches and n/v/d.
Diagnosis:
Rapid flu test-
PCR- is very specific and few places of subtypes.
catches most positive cases, n
High sensitivity 70%
not many false positives,
high specificity 90%
Influenza treatment:
Tamiflu (which is becoming resistant)
Relenza