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35 Cards in this Set

  • Front
  • Back
Fungi rank in terms of microbial pathogens
2nd largest to parasites
Major differences between fungi and human cell are fungi possess _____and ____molecules
cell wall
beta-glucan
the 2 forms of fungi are __a___, the invasive stage, which is present at approx _b___degress, and __c___the bloodstream/systemic infection stage, present at approx _d___degrees
a - hyphae
b - 25
c - yeast
d - 37
UNICELL/BUDDING state of fungi is _____ at ____degrees
yeast 37
multicell, filamentous stagte of fungi is ___at____degrees
hyphae 25
Superficial mycosis fungi use what as a source of nutrients?
keratin
Superficial mycosis has what type of fungi?
dermatophytes
Which 3 are dermatophytes
aspergillus
filamentous
trichophyton
Penicillium
microsporum
tinea
epidermophyton
trichophyton
microsporum
epidermophyton
Aspergillosis
3 characteristic infection types
1____
2_____, often seen in patients w/____
3_____starts pulmonary but can disseminate
allergic
fungus ball
agressive
penicillium marneffei is unique in that it is the only penicillium to...
cause lethal infection
tinea cruris - a
tinea capitis - b
tinea corporis - c
tinea pedis -
tinea barbae
a - jock
b - head
c - anywhere
d - feet
e - beard
Which is an infection that leads to ulceration?
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
sporotichosis
What is an infection leading to pulmonary chronic infection?
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
blasto
which is an infection leading to problems in spleen/marrow/lungs/liver?
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
histoplasmosis
which is infection that is often w/ CNS effect?
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
coccidio
which is an infection leading to chronic granulomatous?
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
paracoccidoi
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
which one's species is dermatitidis?
blasto
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
which one's species is schenckii
sporo
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
which one's species is Capsulatum
histoplasmosis
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
which one's species is immitis
coccidio
Blastomycosis
Sporotrichosis
Histoplasmosis
Coccidiomycosis
Paracoccidiomycosis
which one's species is brasiliensis?
paracoccidio
cryptococus neofromans is spread thru?
inhalation from pigon droppings
what is resp for THRUSH in babies?
candida ablicans
what is resp for denture stomatitis?
candida albicans
4 presentations of oral candidiasis
erethematous
pseudomembranous
angular cheillitis
denture stomatitis
candida infections are often seen wih what bacteria in blood/syst infections?
staph aureus
saccharomyces cerevisieae is a yeast that
helps sugar into alcohol for beer/bread
2 antifungal classes are
azole and polyene
what is the #1 azole drug of choice for oral/vaginal/systemic infections
fuconazole
what are the 2 main polyene drugs?
nystatin, amphotericin
advantage to polyenes?
fungicidal
disadvantage to polyenes?
serious side effects
how do azoles work?
target ERGOSTEROL gene
what is a common genetic mutation site for fungi to be resistant to drugs?
ERG11 gene, (ergosterol)
Overexpression of MDR/CDR gives fungi what advantage?
increased efflux