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13 Cards in this Set
- Front
- Back
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Histoplasmosis mimics which disease?
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resembles miliary tuberculosis
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What are two important characteristics of the pathology of histoplasmosis?
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primary lung process manifest as respiratory ilness and miliary spread
may be primarily in the hilar lymph nodes and may be chronic with cavitation or heal with calcification |
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H. capsulatum is ecologically associated with what types of environments?
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Mississippi / ohio river valey
Southeast US river basins |
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Who gets life threatening infections due to H. capsulatum?
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AIDS patients
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What are the characteristics of the mold and yeast phase of H. capsulatum?
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mold grows on media agar slants at 20-30 degrees; grows as saprophytic mold in soils
Yeast phase present in man, grows on Brain Heart infusion agar or enriched agar at 37 degrees |
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How are Histoplasmosis classified?
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BENIGN INFECTIONS
-usually mild and asymptomatic but rarely causes Symptomatic Primary OPPURTUNISTIC INFECTION - Disseminated Histoplasmosis (immune defect- AIDS) - Chronic Pulmonary Hisotplasmosis (structural Defect) EXCESSIVE FIBROSIS: Healed Primary - Mediastinal Fibrosis or Collagenous |
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What is a characteristic X ray finding in Histoplasmosis?
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diffuse calcification
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B. dermatididis is characterized by what type of tissue form?
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necrotic ulcers due to dissemination (Erythma nodosum)
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What is characteristic of pulmonary disease caused by P. brasiliensis?
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begins abruptly with high fever, cough and respiratory insufficiency
more usual is the anorexia, weigth loss and malaise |
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Whay is the epidemiology of paracoccidioidomycosis?
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South America and Mexico
found in warm, wet tropical areas; tropical or subtropical rainforests most important systemic mycoses in Latin America |
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What is the clinical presentation of paracoccidioidomycosis?
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chronic granulomatous disease and pulmonary disease
extensive fibrosis of the lungs |
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What are the characteristics of the tissue phase and yeast phase of P. brasiliensis?
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tissue phase is budding yeast
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What are the ecology and epidemiology of Coccidioides immitis?
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resides in warm, alkaline arid soils as a saprophyte in the Southwestern United States, Mexico, and Central America
grows 3-4 inches under soil, comes to the surface follwing late spring rains and carried by wind to unsuspecting host (usually a visitor to the region) dark skinned individuals are more susceptible |
