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32 Cards in this Set
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percentage of population in the US that will develop an STD in their lifetime
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at least 50% sometime before they are 35
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Does NOT grow in any culture media. It exhibits undulating motility. "
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Treponema pallidum
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one of the unique properties of treponema pallidum is its undulating motility, what gives this organism this feature?
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endoflagella
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clinical manifestations of syphilis consists of 3 well defined stages which are?
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primary, secondary, tertiary
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the clinical stage of ___________________ presents with a painless sore, ulcer in the genitals it last a few days. It develops slowly over time w some rgional node swelling . In this stage the pt is highly transmissible . The lession eventually heals and resolves w or w/o tx.
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primary syphilis
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What would happen is this patient avoids medical treatment?
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"secodary syphilis, developed a few weeks after primary syphilis
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What are the rare disease manifestations seen?
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"SKIN: skin lesions and gummas
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Besides clinical presentation and history, what additional studies would help you make the diagnosis of syphilis?
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"serology
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if a pt w syphilis p/w positive RPR what would be the next step?
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follow w specific test to confirm
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if a pt being worked up for syphilis presents w a negative RPR, what do you tell the patient?
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either the patient does not have the disease or is inactive
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A pt has been diagnosed w syphilis, when worked up he p/w very high titers of antibodies, what does this indicate in terms of the duration of his disease?
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very high titers indicate the patient has had theactive disease for a sufficient duration to develop a lot of Ab
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What would be the 3 most likely patient situations in which this will occur?"
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"1
the pt was infected and treated |
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this agent causes soft PAINFUL chancres on the genitals plus buboes, gram negative rod.
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Haemophilus ducreyi
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pink rods, and positive culture on chocolate agar. It casues a rare STD in the US but commonly seen in tropical parts of the world.
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chancoird
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Haemophilus ducreyi has this features when seen on chocolate agar
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pink gram + rod
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an male patient c/o swollen and tender inguinal area (the skin and nodes). Also c/o malaise, upon workup the man admits traveling to the tropics.
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lymphogranuloma venereum (LVG)
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this organims is responsible for lymphogranuloma venereum
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different strain of Chlamydia trachomatis than those associated with urethritis and PID
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circular dsDNA that causes anogenital warts and is associated w cervical intraepithelial neoplasia
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HPV
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how do certain types of HPV viruses evolve to malignancies
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the viral DNA is integrated into the host genome
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HPV DNA types that have been found responsible for a high percentage of cervical carcinoma. Which ones are low risk
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"HPV 16, 18 are high risk
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this ds DNA virus causes anogenital warts and some types of cervical cancer is member of the papovavirus
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Human Papilloma Virus
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What do you expect to find?"
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microscopic exam of a wet mount prep looking for motile protozoan parasite with a pear shape. And or perform a "whiff test"
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motile pear shaped protozoan parasite seen in wet mount
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Trichomona vaginalis
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typical clinical presentation of trichomoniasis in women and in men
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"women c/o itchy malodorous yellow green d/c, erythematous cervix
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this protozoan parasite life cycle includes only trophozoite stage and has multiple active flagella
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Trichomona vaginalis
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produces a bad
smelling, red ("strawberry") inflammation with a thin discharge. If you are inexperienced and happen to biopsy it, you'll see only superficial inflammation.The protozoan is easily seen in wet mounts, looking like a bouncing pear moving about with wiggly flagella. |
Trichomonas vulvovaginitis
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bacterial vaginosis caused by an anaerobic rod, characterized by a malodorous vaginal discharge
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Mobiluncus
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these gram variable rods bacteria cling to epithelial cells in the genital tract producing the appearance of clue cells. They are the most common cause of bacterial vaginosis
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Gardnerella vaginalis
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6 possible factors that could contribute to the development of BV
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"1 multiple sexual partners
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this condition is caused by loss of the protective lactobacilli in the genital tract leading to the overgrowth of gram variable rods, and anaerobic rods
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bacterial vaginois caused by garnerella vaginalis and mobiluncus
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this large enveloped dsDNA virus causes multiple vesicular ulcerative lesions on the genital tract, lesions may be painful and a/w flu like symptoms
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Herpes Virus 2
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diagnostic tests (3) for herpes virus 2 and what would you expect to find
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"Tzank smear: multinucelated giant cells in herpetic lesions after staining with Wright
Giemsa |