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32 Cards in this Set

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percentage of population in the US that will develop an STD in their lifetime
at least 50% sometime before they are 35
Does NOT grow in any culture media. It exhibits undulating motility. "
Treponema pallidum
one of the unique properties of treponema pallidum is its undulating motility, what gives this organism this feature?
endoflagella
clinical manifestations of syphilis consists of 3 well defined stages which are?
primary, secondary, tertiary
the clinical stage of ___________________ presents with a painless sore, ulcer in the genitals it last a few days. It develops slowly over time w some rgional node swelling . In this stage the pt is highly transmissible . The lession eventually heals and resolves w or w/o tx.
primary syphilis
What would happen is this patient avoids medical treatment?
"
"secodary syphilis, developed a few weeks after primary syphilis
What are the rare disease manifestations seen?
"
"SKIN: skin lesions and gummas
Besides clinical presentation and history, what additional studies would help you make the diagnosis of syphilis?
"serology
if a pt w syphilis p/w positive RPR what would be the next step?
follow w specific test to confirm
if a pt being worked up for syphilis presents w a negative RPR, what do you tell the patient?
either the patient does not have the disease or is inactive
A pt has been diagnosed w syphilis, when worked up he p/w very high titers of antibodies, what does this indicate in terms of the duration of his disease?
very high titers indicate the patient has had theactive disease for a sufficient duration to develop a lot of Ab
What would be the 3 most likely patient situations in which this will occur?"
"1
the pt was infected and treated
this agent causes soft PAINFUL chancres on the genitals plus buboes, gram negative rod.
Haemophilus ducreyi
pink rods, and positive culture on chocolate agar. It casues a rare STD in the US but commonly seen in tropical parts of the world.
chancoird
Haemophilus ducreyi has this features when seen on chocolate agar
pink gram + rod
an male patient c/o swollen and tender inguinal area (the skin and nodes). Also c/o malaise, upon workup the man admits traveling to the tropics.
lymphogranuloma venereum (LVG)
this organims is responsible for lymphogranuloma venereum
different strain of Chlamydia trachomatis than those associated with urethritis and PID
circular dsDNA that causes anogenital warts and is associated w cervical intraepithelial neoplasia
HPV
how do certain types of HPV viruses evolve to malignancies
the viral DNA is integrated into the host genome
HPV DNA types that have been found responsible for a high percentage of cervical carcinoma. Which ones are low risk
"HPV 16, 18 are high risk
this ds DNA virus causes anogenital warts and some types of cervical cancer is member of the papovavirus
Human Papilloma Virus
What do you expect to find?"
microscopic exam of a wet mount prep looking for motile protozoan parasite with a pear shape. And or perform a "whiff test"
motile pear shaped protozoan parasite seen in wet mount
Trichomona vaginalis
typical clinical presentation of trichomoniasis in women and in men
"women c/o itchy malodorous yellow green d/c, erythematous cervix
this protozoan parasite life cycle includes only trophozoite stage and has multiple active flagella
Trichomona vaginalis
produces a bad
smelling, red ("strawberry") inflammation with a thin discharge. If you are inexperienced and happen to biopsy it, you'll see only superficial inflammation.The protozoan is easily seen in wet mounts, looking like a bouncing pear moving about with wiggly flagella.
Trichomonas vulvovaginitis
bacterial vaginosis caused by an anaerobic rod, characterized by a malodorous vaginal discharge
Mobiluncus
these gram variable rods bacteria cling to epithelial cells in the genital tract producing the appearance of clue cells. They are the most common cause of bacterial vaginosis
Gardnerella vaginalis
6 possible factors that could contribute to the development of BV
"1 multiple sexual partners
this condition is caused by loss of the protective lactobacilli in the genital tract leading to the overgrowth of gram variable rods, and anaerobic rods
bacterial vaginois caused by garnerella vaginalis and mobiluncus
this large enveloped dsDNA virus causes multiple vesicular ulcerative lesions on the genital tract, lesions may be painful and a/w flu like symptoms
Herpes Virus 2
diagnostic tests (3) for herpes virus 2 and what would you expect to find
"Tzank smear: multinucelated giant cells in herpetic lesions after staining with Wright
Giemsa