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31 Cards in this Set

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Protazoans are single cell. can have one to many _____ in one cell
nuclei
two “stages” of protozoans
trophozoite – metabolically active stage
-stage that causes pathology
cyst – dormant stage, often found in stool
Protozoans characterized by ________
method of movement
pt w/ history of diarrhea presents w/ liver dz. Stool analysis shows cysts/ trophozoites in stool. What is a likely dz?
Entamoeba histolytica
Entamoeba histolytica spreads by ________
fecal-oral contamination
Entamoeba histolytica usually involves ingestion of a ____
cyst
Entamoeba histolytica develops into _______ in the colon
trophozoite
Entamoeba histolytica damages intestinal epithelium and ingests _____
RBCs
Entamoeba histolytica doesn’t eat ____
WBCs
Entamoeba histolytica may cause diarrhea to severe _____
dysentery
In a small percentage of patients Entamoeba histolytica can move to can move to ______ like the liver and lungs, occasionally skin or heart
extraintestinal locations
Entamoeba histolytica morphology is:
__ nucleus in troph
__ nuclei in cyst
1
4
Other Entamoeba species include Entamoeba coli which is _______ and Entamoeba gingivalis which ______
non-pathogenic
eats WBC
Giardia lamblia infects _______
small intestine
-trophozoite is pear-shaped with two nuclei.
-cyst is oval with four nuclei
-estimated to be the leading protozoan cause of diarrhea
Giardia lamblia
pt complains of “explosive” watery stools (foul-smelling), flatulence, nausea
what is the dx?
How do you dx?
Giardia lamblia pathology

identification of cysts in stool
_______ implicated
as reservoir host of Giardia
beavers
Balantidium coli causes ______(ciliar dysentery)
Balantiasis
Balantidium coli is a ______ organism
ciliated
Balantidium coli is the ________protozoan parasite of humans
largest
Balantidium coli has two _____:
macronuclei – “metabolic” activities
micronuclei – sexual reproduction
nuclei
in Balantidium coli ______ and ____ look similar
trophozoite
cyst
_____ are usual Balantidium coli reservoir for human infections
pigs
diagnosis of Balantidium coli
identification of the parasite
Cryptosporidium hominis and C. parvum are non-motile protozoan. They are problematic for immunosuppressed
opportunistic infections and a major problem for the _______ because there is no effective therapy
immunosuppressed
infective stage of Cryptosporidium parvum
Oocyst –
Toxoplasma gondii is also a non-motile protozoan spread by fecal-oral contamination via cats (definitive host). This is also a opportunistic infection and problematic for the ________.
immunosuppressed
In most humans Toxoplasma gondii is an asymptomatic infection. Those with ____ have higher incidence of toxoplasma encephalitis (TE). ____ in AIDS patients seems to be protective
MHC-DQ3
DQ1
in T. gondii bradyzoites (slow dividing stage) can develop in fetal brain and result in ________
(blindness, mental retardation, etc.)
congenital defects
T. gondii bradyzoites can also cause CNS damage in ______
AIDS patients
Toxoplasma gondii is also associated with transmission during ________
organ transplantation