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18 Cards in this Set
- Front
- Back
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Cowdry type A
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Herpetoviridae
acid fast found in nucleus |
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Negri bodies
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Rabies virus
found in cytoplasm |
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Guarnieri Bodies
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Poxviridae
found in cytoplasm "loaf of bread" |
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What viruses decrease immune response and create cytokines?
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cytomegalovirus
HIV Rhinovirus RSV |
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What cytokine is generated by cytomegalo, HIV, rhinovirus, RSV that decreases immune response?
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IL-10
This increases expression of CCR5- chemokine receptor |
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What viruses augment immune response and what cytokine do the create?
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1) Ebola Virus
2) Marburg Virus increases TNF-α causing bp drop and leakiness of capillaries |
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Name 4 results of infection with a virus.
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1. cytocidal
2. steady-state 3. hyperplasia 4. transformation |
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Give an example of cytocidal virus.
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Rhabdoviridae-
binds nicotinic Ach receptor results in cell death |
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Give an example of steady-state virus.
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Herpes-simples type 1 and 2
non-cytocidal |
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Give an example of hyperplasia as a result of infection with a virus.
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Papovavirida
warts, non-malignant tumor |
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Give an example of transformation in virus infection.
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Epstein-barr virus
Burkitt's lymphona tumor/oncogenesis |
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Name 3 causes of systemic viral infection.
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1. Drug abuse
2. Insect vectors 3. Hospitals |
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Name antibody type generated during acute phase viremia
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IgM
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Name antibody type generated during convalescent phase viremia
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IgG
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Name antibody generated during a localized viral infection
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IgA secretory antibody
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Name 2 compounds that do not readily inactivate viruses
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1. quaternary ammonium compounds
2. Iodine |
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Name 4 compounds that readily inactivate viruses.
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1. strong chlorine solution
2. formalin 3. phenol 4. strong oxidizers |
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How long at at what temp must you autoclave things?
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100 deg C for 30 minutes
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