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20 Cards in this Set
- Front
- Back
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M. Leprae is similar to ________.
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M. Tuberculosis
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M. Leprae can or can not be cultured?
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M. L. can not be cultured on any media and for that reson it is an exception to Koch's postulates.
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M. Leprae grows more or less than any other organism in the human system?
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more abudantly
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There are 2 forms of leprosy, _______( ______ form) and _______ form.
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Tuberculoid (Anasthetic form) in which the area loses pigment and sensation, and Lepromatous (nodular form) which shows granulomatous response - large disfiguring lepromas form
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M. Leprae is the only organism that destroys _______ _____, ______, and ______ _______.
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peripheral tissue, skin, and mucous membranes
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M. Leprae has predilection for warmer or colder parts of the body?
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colder parts - it slowly deforms the hands and feet
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Leprosy is diagnosed by _____ or by finding the organism in _____ _____ stained smears.
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PCR, acid fast
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Treatment for leprosy includes _____, _____, and ______.
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dapsone, clofazimine, and rifampin
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Is there a vaccine available for leprosy?
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No, although people who receive dapsone treatment can live an almost normal life
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Though leprosy has declined, it still remains in what seven countries?
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Angola, Brazil, India, Indonesia, Burma, Nepal, Niger
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Approximately _______ cases of leprosy exist today.
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2.5 million
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Name the 5 countries that account for 90% of leprosy cases. (from book)
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Brazil, Madagascar, Mozambique, Tanzania, and Nepal
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M. Leprae organism grows in ________ and has a long or short division cycle?
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grows in macrophages and has a long division cycle (12 days). Incubation can take years or even decades
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Upon treatment of leprosy, a patient can be allergic to the antigenic material released from the killed organism. This is called ________.
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ENL (erythema nodusum leprosum)
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Is the lepromin test positive for both forms of leprosy?
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No. it is positive in most cases of tuberculoid leprosy, but negative in the lepromatous form.
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Is there a connection between M. Leprae and M. Lepraemurium (rat leprosy)?
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No. Human leprosy is transmitted by prolonged contact with infected patients or by inhaling sputum or nasal discharge. Although indirect contact with bugs has been inferred.
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Growing the M. Leprae bacterium in an alternative host such as __________ has been useful because it grows faster in these animals.
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armadillos
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Victims of leprosy were once isolated in hospitals called _________.
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leprosariums
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Which form of leprosy is considered to have nervous system involvement?
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tuberculoid
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Leprosy may cause a disfiguring of the face known as________?
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Lion face
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