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99 Cards in this Set

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What often accompanies Acute Diarrhea?


 Abdominal pain/cramping


 Nausea / Vomiting


 Dehydration

What is the causative agent of Salmonella?

[Salmonellosis, gastroenteritis, orenteric fever]


(Acute Diarrhea)

Salmonella enterica

How does salmonella enterica appear in culture?


(Acute Diarrhea)


motile, gram- rod


urease-


lactase-


hydrogen sulfide+

What do the following tests show (+ or - ) urease , lactase, hydrogen sulfide

How is Salmonella transmitted?

(Acute Diarrhea)

Consumption of contaminated food
What are the signs and symptoms of Salmonella ?

(Acute Diarrhea)

 Fever (severe)

 Septicemia (severe)


 Gastroenteritis


 Vomiting


 Diarrhea


 Mucosal irritation


 Hematochezia (blood in stool)

What are the preventative measures for Salmonella?

(Acute Diarrhea)

Avoid the bacterium

How is Salmonella treated?


(Acute Diarrhea)



Electrolyte and fluid replacement




(antibiotics in immune comp.)

What is the causative agent of Shigella?

(Acute Diarrhea)

Shigella sp.
what is the appearance of Shigella in culture?

(Acute Diarrhea)

non-motile, gram- rods
urease-
lactase-
hydrogensulfide-




*Very similar to E. coli*

What are the signs and symptoms of Shigella?

(Acute Diarrhea)

Watery stools

 Fever


 Nausea and vomiting


 Occult blood in stool


 Bloody diarrhea (dysentery)


 Sometimes mucous in stool as well

How is Shigella transmitted?

(Acute Diarrhea)

Usually through fecal oral route

 Can be person-person (smallinfectious dose)


 Associated with crowding,malnutrition, and lax sanitation

How is Shigella prevented?

(Acute Diarrhea)

good hygiene



avoid chronic carriers

What is the causative agent of E. coli?

(Acute Diarrhea)

Escherichia coli

(O157:H7 and O104:H4 strains, enterohemorrhagic E. coli (EHEC), or Shiga-like toxin producing E. coli(STEC))

what is the appearance of E. coli in culture?

(Acute Diarrhea)

motile gram- rod

urease-


lactase+


hydrogensulfide-

What are the signs and symptoms of E. coli?

(Acute Diarrhea)

mild symptoms

gastroenteritis


dysentery

How is E. coli treated?

(Acute Diarrhea)

***No antibiotics***

Supportive therapy

How is E. coli diagnosed?

(Acute Diarrhea)

Stool culture

ELISA


PCR

What is a possible complication of E. coli?

(Acute Diarrhea)

hemolytic-uremic syndrome (HUS)
What does hemolytic-uremic syndrome (HUS) affect and what are the symptoms?

(Acute Diarrhea)

E. coli infects kidney

hematuria, pain, low or no urineoutput


anemia


nervous system problems


kidney failure

How is E. coli transmitted?

(Acute Diarrhea)

mostly comes from food sources
What is the causative agent of Campylobacter?

(Acute Diarrhea)

Campylobacter jejuni
What is the appearance in culture of Campylobacter jejuni?

(Acute Diarrhea)

gram - spirillum
what is Campylobacter?

(Acute Diarrhea)

most common cause of diarrheain the US
How is campylobacter transmitted?

(Acute Diarrhea)

acquired from: contaminatedwater, milk, meat, and chicken
what is a possible complication of campylobacter?

(Acute Diarrhea)

may cause paralysis: Guillan Barre syndrome
what is the treatment for campylobacter?

(Acute Diarrhea)

**usually supportive (hydration andelectrolytes)**



antibiotics only if extreme or IC pt.

what is the causative agent for C. diff?

(Acute Diarrhea)

Clostridium difficile
what is the appearance of clostridium difficile in culture?

(Acute Diarrhea)

gram+ rod (endospore forming)
what are the signs and symptoms for clostridium difficile?

(Acute Diarrhea)

diarrhea

cramping


fever


leukocytosis


what is a possible complication of clostridium difficile?

(Acute Diarrhea)

pseudomembranous colitis bowel perforation

death

how is clostridium difficile transmitted?

(Acute Diarrhea)

endogenous

usually the result of broad-spectrumantibiotic treatment (ampicillin,clindamycin, or cephalosporins)

how is clostridium difficile diagnosed?

(Acute Diarrhea)

ELISA

PCR

How is clostridium difficile treated?

(Acute Diarrhea)

antibiotics, fluid replacement(mild)

Dificid (more serious cases)


fecal transplant (new)

what is the causative agent for Vibrio cholerae?

(Acute Diarrhea)

Vibrio cholerae
what is the appearance of Vibrio cholerae in culture?

(Acute Diarrhea)

gram - flagellated vibrio
what are the signs and symptoms of Vibrio cholerae?

(Acute Diarrhea)

vomiting and watery diarrhea followed by rice-water stool(mucosa)

fluid loss can = 1L/hr


loss of blood volume, acidosis, andpotassium depletion muscle cramps, thirst, flaccid skin,sunken eyes, coma

how is Vibrio cholerae transmitted?

(Acute Diarrhea)

warm, monsoon, alkaline, and salineconditions favor migration usually come from contaminatedwater sources

Top 7 in morbidity and mortality world wide

how is Vibrio cholerae diagnosed?

(Acute Diarrhea)

clinical symptoms usually sufficient

can be isolated from stool samples

how is Vibrio cholerae prevented?

(Acute Diarrhea)

short-term vaccines can be given totravelers to endemic regions sanitation is key
how is Vibrio cholerae treated?

(Acute Diarrhea)

replacement of electrolytes and fluids isessential

used to depend on IV drip method


now uses oral rehydration therapy (ORT)

what is the causative agent for cryptosporidiosis?

(Acute Diarrhea)

Cryptosporidium sp.
what is the appearance of Cryptosporidiumin culture?

(Acute Diarrhea)

acid-fast intestinal protozoan
what are the signs and symptoms of Cryptosporidium?

(Acute Diarrhea)

gastroenteritis

headache


sweating


vomiting


abdominalcramps


diarrhea

how is Cryptosporidium treated?

(Acute Diarrhea)

treatment not usually needed
how is Cryptosporidium transmitted?

(Acute Diarrhea)

commonly isolated from HIV+ pts.

zoonosis (pigs, poultry, cows) water contaminated with oocystoften associated with swimmingpools

how is Cryptosporidium diagnosed?

(Acute Diarrhea)

detected in fecal samples usingELISA or acid-fast staining
what is the causative gent for Rotavirus?

(Acute Diarrhea)

Rotavirus
what are the signs and symptoms of Rotavirus?

(Acute Diarrhea)

watery diarrhea

fever


vomiting


dehydration


hypovolemic shock

how is Rotavirus transmitted?

(Acute Diarrhea)

transmitted by fecal-oral routethrough contaminated water, food,and fomites
how is Rotavirus prevented?

(Acute Diarrhea)

Rotarix or RotaTeq vaccines
how is Rotavirus treated?

(Acute Diarrhea)

Rehydration

Oral rehydration solution


IV/NG tube rehydration fluids

how is Rotavirus diagnosed?

(Acute Diarrhea)

ELISA (stool sample)

PCR


electron microscopy

Cyclospora cayetanensis is caused by what type of organism (bacteria, virus, protazoan etc.) ?

(Chronic Diarrhea)

protozoan
how is Cyclospora cayetanensis transmitted?

(Chronic Diarrhea)

transmittedby fecal-oral route

outbreaks have been tracked to raspberries,salads made with fresh greens, and drinkingwater

how is Cyclospora cayetanensis treated?

(Chronic Diarrhea)

antibiotics
What can Giardia lamblia cause? What are the signs/symptoms?
Chronic Diarrhea

(long-term diarrhea, abdominal pain,and flatulence)

what is Giardia lamblia? (bacteria, virus, etc.)

and where is it found?

flagellated protozoan found in freshwater including Finger Lakes

heart-shaped trophozoite

how is Giardia lamblia treated?
antibiotics
What can Entamoeba histolytica cause? (signs/symptoms)
Chronic Diarrhea



may also target liver and lungs dysentery


abdominal pain


fever


weight loss

What are some complications ofEntamoeba histolytica?
perforations,hemorrhage, appendicitis, amoebomas
How is Entamoeba histolytica transmitted?

comes from ingesting contaminated foodand water


**chronic carriers shed cysts in their feces **

How is Entamoeba histolytica prevented?
water treatment; oftenboiling or iodine
How is Entamoeba histolytica treated?
antiprotozoal and replacement of fluids and electrolytes
what is the causative agent for Mumps?
Mumps virus (Paramyxovirus)
What are the sings and symptoms of mumps?
fever, nasal discharge, malaise, and muscle pain

gopher-like swelling parotids (salivary gland)


also invades testes, ovaries, thyroids gland,meninges, pancreas, heart, and kidney

how is mumps transmitted?
salivary and respiratorysecretions
how is mumps prevented?
MMR vaccine
how is mumps treated?
Treatment to relieve fever, dehydration, and pain
what are possible complications of mumps?
testicular inflammation meningitis

pancreatic inflammation


brain inflammation

what is the causative agent for Hepatitis?
Hepatitis A-E

cytomegalovirus


Epstein-Barr virus

what are the general signs and symptoms of hepatitis?
Inflammatory disease that affects the liver causing Jaundice
how are hepatitis A and E transmitted?
Fecal-oral transmission because of Poor sanitation or personalhygiene
what are the signs and symptoms of hepatitis A and E?
Subclinical or flu-like symptomswith jaundice and enlarged liver
how are hepatitis A and E prevented?
vaccination
how are hepatitis A and E treated?
no specific medicine used;hydrate and avoid liver irritants
what are the signs and symptoms of hepatitis B and D?
Fever, chills, malaise, anorexia,abdominal discomfort, diarrhea, andnausea
what are complecations associated with hepatitis B and D?
May cause a life threatening illness

Potential cancer issues as well

how are hepatitis B and D transmitted?
even smallamounts of blood and can remainactive in dry blood

Gets through the skin barrier

how are hepatitis B and D prevented?
Vaccination available
how are hepatitis B and D treated?
Symptomatic treatment
what are the signs and symptoms of hepatitis C ?
Signs similar to Hep B, but much more likelyto become chronic

Can cause cancer and liver failure

how is hepatitis C transmitted?
Acquired through blood and body fluids
how is hepatitis C prevented?
avoid contact with body fluids of an infected patient

No vaccine available

how is hepatitis C treated?
ribavirin and interferon

New protease inhibitor drugs available

what is the causative agent of pin worms? (proper name for pin worm)
Enterobius vermicularis
what are the signs and symptoms of pin worms?
anal itching

May be asymptomatic or causesleep disturbances, nausea,and/or diarrhea

how are pin worms treated?
anthelmintic drugs
how are pin worms diagnosed?
the tape test
how are pin worms transmitted?
fecal-oral route
Taenia solium is the proper name for what helminth?
Pork tapeworm
how are tapeworms transmitted?
eating meat contaminatedwith eggs
what are the signs and symptoms of tapeworms?
Usually asymptomatic, but maycause abdominal pain andnausea
how are tapeworms diagnosed?
May find proglottids or eggs instool for diagnosis

ELISA to detect tapeworm Abs

how are tapeworms treated?
anthelmintic drugs
what is the causative agent of Schistosomiasis?
Schistosomajaponicum or Schistosoma mansoni
what are the signs and symptoms of Schistosomiasis?
Enlarged liver, liver disease,enlarged spleen

can invade heart and nerves

how is Schistosomiasis diagnosed?
ID through eggs in stool andintestinal scarring
how is Schistosomiasis treated?
anthelmintic drugs
how is Schistosomiasis transmitted?
Invades intact skin

usually through feet (stepping on a snail)