Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
36 Cards in this Set
- Front
- Back
|
Subcutaneous Mycoses: Characteristics
|
Localized infections of deeper dermal layers, cornea, muscle, bone, and connective tissues
may involve immune response found in soil, wood, vegetation, spread thru skin trauma |
|
|
Lymphocutaneous sporotrichosis:
E. Agent |
Sporothrix schenckii
|
|
|
Lymphocutaneous sporotrichosis:
Transmission/VF |
Traumatic inoculation from soil or decaying vegetation in outdoor work environments
can be zoonotic |
|
|
Lymphocutaneous sporotrichosis:
Primary Diagnosis |
Painless Lymphatic nodules (wks after primary ulceration)
linear along lymphatic drainage path |
|
|
Lymphocutaneous sporotrichosis:
Lab ID |
Micro, cx infected pus or tx, immunological test
confirm w/ thermally-induced dimorphic transition |
|
|
Lymphocutaneous sporotrichosis:
Outcome/ Treatment |
Oral KI in developing countries
itraconazole |
|
|
Lymphocutaneous sporotrichosis:
Misc. |
Thermically dimorphic
@ 25o- grows as mold (narrow hyaline septate w/ conidia) @37o & in tx- oval to elongated yeast, pleomorphic |
|
|
Chromoblastomycosis:
E. Agent |
Cladosporium, fonsecaea, Exophiala, Phialophora, & Cladophialophora
|
|
|
Chromoblastomycosis:
Transmission/VF |
Freq in tropical climates
related to warm, moist enviro & absence of protective clothing & footwear |
|
|
Chromoblastomycosis:
Primary Diagnosis |
Mult lg cauliflower-like growths
hyperkeratotic, fibrosis, lymphoadema |
|
|
Chromoblastomycosis:
Lab ID |
Difficult to ID
Clinical presentation, brown muriform cells in histopath Preps, cultivation |
|
|
Chromoblastomycosis:
Outcome/ Treatment |
Chemotherapy difficult due to advanced state before patients present
Itraconazole & terinafine. |
|
|
Chromoblastomycosis:
Misc. |
All are dematiaceous sepatate molds
Appear as uniform brown muriform cells with pigmented hyphae in host tx infx usually advanced before symptoms present |
|
|
Eumycotic mycetoma:
E. Agent |
Actinomycotic mycetoma
Also caused by Acremonium, Fusarium, Madurella, Exophiala, & Scedosporium spp. |
|
|
Eumycotic mycetoma:
Transmission/VF |
Percutaneous inoculation of foot or hand
Problem in tropics w/ low rainfall |
|
|
Eumycotic mycetoma:
Primary Diagnosis |
Sm, painless nodules or plaques
Chronic inflam & fibrosis w/ serosamuinous fluid drainage Destruction of bone & muscle |
|
|
Eumycotic mycetoma:
Lab ID |
Micro- granulations w/ hyphae in tissue
Culture for species ID |
|
|
Eumycotic mycetoma:
Outcome/ Treatment |
No Good Chemotherapy
Amputation becomes necessary |
|
|
Eumycotic mycetoma:
Misc. |
Mult granulomas & abscesses w/ lg aggregates of hyphae w/ thick walls & hard ECM material
Contain septate & either dematatiaceous or hyaline |
|
|
Subcutaneous zygo-mycosis:
Conidiobolus coronatus E. Agent |
Conidiobolus coronatus
Infects Facial area in Adults |
|
|
Subcutaneous zygo-mycosis:
Conidiobolus coronatus Transmission/VF |
In tropical enviro of Africa & India
In plant debris Inhalation of spores that infect nasal cavity, sinus & facial tx |
|
|
Subcutaneous zygo-mycosis:
Conidiobolus coronatus Primary Diagnosis |
Swelling of upper lip & face
|
|
|
Subcutaneous zygo-mycosis:
Conidiobolus coronatus Lab ID |
biopsy of affected tissues and demonstration of eosinophils and hyphae surrounded by Splendore – Hoeppli material
Culture of Infected Tissue |
|
|
Subcutaneous zygo-mycosis:
Conidiobolus coronatus Outcome/ Treatment |
Saturated KI or itraconazole
|
|
|
Subcutaneous zygo-mycosis:
Conidiobolus coronatus Misc. |
Hyphae are thin-walled & sparsely septate
appear as fragments assoc w/ inflammation & lots of eosinophil presence |
|
|
Subcutaneous zygo-mycosis:
Basidiobolus ranarum E. Agent |
Basidiobolus ranarum
Proximal Limb are in Children |
|
|
Subcutaneous zygo-mycosis:
Basidiobolus ranarum Transmission/VF |
In tropical enviro of Africa & India
In plant debris Traumatic inoculation of thighs, buttocks, or trunk |
|
|
Subcutaneous zygo-mycosis:
Basidiobolus ranarum Primary Diagnosis |
Movable, rubbery masses can ulcerate after expanding in the hips, trunk, & thighs
|
|
|
Subcutaneous zygo-mycosis:
Basidiobolus ranarum Lab ID |
biopsy of affected tissues and demonstration of eosinophils and hyphae surrounded by Splendore – Hoeppli material
|
|
|
Subcutaneous zygo-mycosis:
Basidiobolus ranarum Treatment/ Outcome |
Saturated KI or itraconazole
|
|
|
Subcutaneous phaeohypho-mycosis:
E. Agent |
Dematiaceous fungi
|
|
|
Subcutaneous phaeohypho-mycosis:
Transmission/VF |
Traumatic percutaneous inoculation w/ soil, plant, or wood material
|
|
|
Subcutaneous phaeohypho-mycosis:
Primary Diagnosis |
Localized inflammatory cyst on feet & legs
Indurated pigmented plaques |
|
|
Subcutaneous phaeohypho-mycosis:
Lab ID |
histopathologic examination of cysts to observe inflammation and fibrous capsule, granulomatous reaction, and central necrosis
|
|
|
Subcutaneous phaeohypho-mycosis:
Outcome/ Treatment |
Surgical excision of cysts and itraconazole for plaque-like lesions
|
|
|
Subcutaneous phaeohypho-mycosis:
Misc. |
Dematiaceous fungi w/ septate, irregular hyphae & yeast forms
|
