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89 Cards in this Set
- Front
- Back
e.coli gram/shape
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gram- rod
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pseudomonias aeruginosa--stain, shape
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gram- rod
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staphylococcus aureus, stain and shape
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gram+ rod
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e. coli full name
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escherichia coli
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e. coli oxygen
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facultative
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pseudomonias aeruginosa--oxygen
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strict aerobe
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e. coli--nosocomial cause of
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pneumonia , wound infections
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pseudomonias aeruginosa--nosocomial cause of
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wound infections (burn victims), pneumonia (CF & compromised patients), UTI
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staphylococcus aureus--nosocomial cause of
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pneumonia
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clostridium difficle--nosocomial cause of
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life-threatening diarrhea
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staphylococcus aureus--community cause of (3)
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TSS, Food intox, skin infections that spread to other organs
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pseudomonias aeruginosa--other notes
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Beta hemolysis on blood agar. Coagulase positive
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Clostridium difficle--grows when ______ flora is eliminated, such as by antibiotics
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intestinal
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Clostridium difficle--rod forms _____, which produce ______
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endotoxins, exotoxins
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clostridium difficle--occurs in which individuals?
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hospitalized as well as healthy individuals
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3 subgroups of beta lactams
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penicillins, cephalosporins, carbapenems
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endotoxin--secreted from, type of infection, stain
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lipid secreted from lysed cell, systemic infection, gram -
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ex of beta lactam
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penicillin, cephalosproin, carbapenem
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exotoxin
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Protein secreted from cell, specific target, gram +
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food infection
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bacteria causes food associated illness
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food toxicity
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exotoxin causes food associated illness
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microbes that cause disease via exotoxin
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clostridium tetani and clostridium botulinium
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mode of action of beta lactam
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damage cell membrane
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3 parts of virus
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envelope + capsid + nucleic acid
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envelope (virus) made of
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lipid w/ embedded proteins (and sometimes carbs too)
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capsid (virus) made of capsid
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Protein (subunits are called capsomeres)
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two shapes of viruses
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helical and icosahedral
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(+) ssRNA
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same sequence as mRNA
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(-) ssRNA
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complementary to mRNA
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virus life cycle--1st two
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attchment and entry (DNA w or w/o capsid)
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virus life cycle--3 & 4
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biosynthesis and assembly/packaging
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virus life cycle--last step
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Release of virions
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dsDNA shapes
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linear or cyclic
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ssDNA shapes
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cyclic only
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herpes: shape
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linear
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herpes: molecule strand and type
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dsDNA
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herpes: covering
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enveloped
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HHV8 causes
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Kaposis sarcoma
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complications of epstein-barr (in herpes family)
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burkitts lyphoma in Africa
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CMV, in herpes family, stands for
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cytomegalovirus
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CMV-caused disease associated with? Symptoms?
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AIDS; fever, encephalities, blindness
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3rd drug for treating herpes
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famicyclovir
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4 ways of diagnosing HIV
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ELISA, Western blot, oraquick, detect antigens or N.A.
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opportunistic infections assosicated with AIDS (3)
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Kaposis sarcoma, pneumcystic pneumonia, thrush
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how do antiretrovirals work? (2)
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block action of viral proteins. Some inhibit enzymes.
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long name for AZT
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Nucleoside Analog Reverse Transcriptase Inhibitor
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Nevirapine, which prevents AIDS transmission from mother to child, belongs to what group of antiretrovirals?
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Non-nucleoside reverse transcriptase inhibitors
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very expensive AIDS treatment
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fusion inhibitor
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newest AIDS treatment
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CCR5 inhibitor
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two other AIDS drugs
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Protease and Integrase inhibitors
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ELISA stands for
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Enzyme Linked ImmunoSorbent Assay
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how does ELISA work?
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use enzyme reactions as indicators
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how does chemokine coreceptor work?
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from host cell, it connects with viral cells glycoprotein spike
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provirus
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DNA that is hidden in host cells chromosome (HIV)
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virion
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A complete, fully developed, infectious viral particle
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virion composed of
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NA + protein coat.
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what does virion protect?
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Protects virus from the environment
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CCR5 and CXCR4
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two best known chemokine chemoreceptors
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virions can be used to classify _______
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viruses
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pandemic /epidemic characteristics (4)
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1) causes serious illness 2) Infects humans 3) easily spread amongst humans 4) antigenic variation
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characteristics of FluMist vaccine
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nasal spray, attenuated
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characteristics of standard flu vaccine
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injected, inactivated
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what is the difference between avian and human influenza?
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the sialic acids, found on the surface of epithelial cells, are different
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IL-1; IL-6
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assist in inflammation: cause fever and helps other immune cells to work better
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IL-2 -kine
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T cell growth factor during activation
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IL-3, 5, 7
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(nothing specific)
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IL-4 -kine
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helps B cells
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IL-8 -kine
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recruits more phagocytes during inflammation
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attentuated vaccine
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alive but weakened virus
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Tox-oid vaccine
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inactivated exotoxin
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subunit vaccine
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part of microbe is used; possibly genetically engineered
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conjugated vaccine
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polysaccharide vaccine + protein carrier
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conjugated vaccine & children
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stimulates a better response in children
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dendritic cell vaccine
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dentritic cell grown in lab
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what is added to dentritic cell in the DC vaccine?
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antigen from tumor or microbe
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bordatella pertusis in old DPT vaccine--what type of vaccine?
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killed
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injected/salk polio; standard flu shot--what type of vaccine?
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inactivated
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MMR; varicella; sugar/sabin polio; rotateq vaccine--what type of vaccine?
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attenuated
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diphtheria; tetanus: DPT, DTaP, Tdap--what type of vaccine?
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toxoid
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New pertussis, baby Dtap; Tdap for older children and up, Hep B, malaria --what type of vaccine?
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subunit
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two flu treatments that slow replication (by inhiting separation of virus from host)
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amantadine and rimatadine
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Generic for Relenza
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zanamavir
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Generic for Tamiflu
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osteltamivir
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flu treatment, blocks NA action, inhaled--brand name
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Relenza
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flu treatment, blocks NA action, oral--brand name
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Tamiflu
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flu treament, blocks NA action, injected, experimental
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Peramivir
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complication of flu, pseudo…
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pseudomonias aeruginosa
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complication of flu, staph…
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Staph aureus
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complication of flu, strep…
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strep pneumonia
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