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89 Cards in this Set

  • Front
  • Back
e.coli gram/shape
gram- rod
pseudomonias aeruginosa--stain, shape
gram- rod
staphylococcus aureus, stain and shape
gram+ rod
e. coli full name
escherichia coli
e. coli oxygen
facultative
pseudomonias aeruginosa--oxygen
strict aerobe
e. coli--nosocomial cause of
pneumonia , wound infections
pseudomonias aeruginosa--nosocomial cause of
wound infections (burn victims), pneumonia (CF & compromised patients), UTI
staphylococcus aureus--nosocomial cause of
pneumonia
clostridium difficle--nosocomial cause of
life-threatening diarrhea
staphylococcus aureus--community cause of (3)
TSS, Food intox, skin infections that spread to other organs
pseudomonias aeruginosa--other notes
Beta hemolysis on blood agar. Coagulase positive
Clostridium difficle--grows when ______ flora is eliminated, such as by antibiotics
intestinal
Clostridium difficle--rod forms _____, which produce ______
endotoxins, exotoxins
clostridium difficle--occurs in which individuals?
hospitalized as well as healthy individuals
3 subgroups of beta lactams
penicillins, cephalosporins, carbapenems
endotoxin--secreted from, type of infection, stain
lipid secreted from lysed cell, systemic infection, gram -
ex of beta lactam
penicillin, cephalosproin, carbapenem
exotoxin
Protein secreted from cell, specific target, gram +
food infection
bacteria causes food associated illness
food toxicity
exotoxin causes food associated illness
microbes that cause disease via exotoxin
clostridium tetani and clostridium botulinium
mode of action of beta lactam
damage cell membrane
3 parts of virus
envelope + capsid + nucleic acid
envelope (virus) made of
lipid w/ embedded proteins (and sometimes carbs too)
capsid (virus) made of capsid
Protein (subunits are called capsomeres)
two shapes of viruses
helical and icosahedral
(+) ssRNA
same sequence as mRNA
(-) ssRNA
complementary to mRNA
virus life cycle--1st two
attchment and entry (DNA w or w/o capsid)
virus life cycle--3 & 4
biosynthesis and assembly/packaging
virus life cycle--last step
Release of virions
dsDNA shapes
linear or cyclic
ssDNA shapes
cyclic only
herpes: shape
linear
herpes: molecule strand and type
dsDNA
herpes: covering
enveloped
HHV8 causes
Kaposis sarcoma
complications of epstein-barr (in herpes family)
burkitts lyphoma in Africa
CMV, in herpes family, stands for
cytomegalovirus
CMV-caused disease associated with? Symptoms?
AIDS; fever, encephalities, blindness
3rd drug for treating herpes
famicyclovir
4 ways of diagnosing HIV
ELISA, Western blot, oraquick, detect antigens or N.A.
opportunistic infections assosicated with AIDS (3)
Kaposis sarcoma, pneumcystic pneumonia, thrush
how do antiretrovirals work? (2)
block action of viral proteins. Some inhibit enzymes.
long name for AZT
Nucleoside Analog Reverse Transcriptase Inhibitor
Nevirapine, which prevents AIDS transmission from mother to child, belongs to what group of antiretrovirals?
Non-nucleoside reverse transcriptase inhibitors
very expensive AIDS treatment
fusion inhibitor
newest AIDS treatment
CCR5 inhibitor
two other AIDS drugs
Protease and Integrase inhibitors
ELISA stands for
Enzyme Linked ImmunoSorbent Assay
how does ELISA work?
use enzyme reactions as indicators
how does chemokine coreceptor work?
from host cell, it connects with viral cells glycoprotein spike
provirus
DNA that is hidden in host cells chromosome (HIV)
virion
A complete, fully developed, infectious viral particle
virion composed of
NA + protein coat.
what does virion protect?
Protects virus from the environment
CCR5 and CXCR4
two best known chemokine chemoreceptors
virions can be used to classify _______
viruses
pandemic /epidemic characteristics (4)
1) causes serious illness 2) Infects humans 3) easily spread amongst humans 4) antigenic variation
characteristics of FluMist vaccine
nasal spray, attenuated
characteristics of standard flu vaccine
injected, inactivated
what is the difference between avian and human influenza?
the sialic acids, found on the surface of epithelial cells, are different
IL-1; IL-6
assist in inflammation: cause fever and helps other immune cells to work better
IL-2 -kine
T cell growth factor during activation
IL-3, 5, 7
(nothing specific)
IL-4 -kine
helps B cells
IL-8 -kine
recruits more phagocytes during inflammation
attentuated vaccine
alive but weakened virus
Tox-oid vaccine
inactivated exotoxin
subunit vaccine
part of microbe is used; possibly genetically engineered
conjugated vaccine
polysaccharide vaccine + protein carrier
conjugated vaccine & children
stimulates a better response in children
dendritic cell vaccine
dentritic cell grown in lab
what is added to dentritic cell in the DC vaccine?
antigen from tumor or microbe
bordatella pertusis in old DPT vaccine--what type of vaccine?
killed
injected/salk polio; standard flu shot--what type of vaccine?
inactivated
MMR; varicella; sugar/sabin polio; rotateq vaccine--what type of vaccine?
attenuated
diphtheria; tetanus: DPT, DTaP, Tdap--what type of vaccine?
toxoid
New pertussis, baby Dtap; Tdap for older children and up, Hep B, malaria --what type of vaccine?
subunit
two flu treatments that slow replication (by inhiting separation of virus from host)
amantadine and rimatadine
Generic for Relenza
zanamavir
Generic for Tamiflu
osteltamivir
flu treatment, blocks NA action, inhaled--brand name
Relenza
flu treatment, blocks NA action, oral--brand name
Tamiflu
flu treament, blocks NA action, injected, experimental
Peramivir
complication of flu, pseudo…
pseudomonias aeruginosa
complication of flu, staph…
Staph aureus
complication of flu, strep…
strep pneumonia