Micro Exam 1 Cont.

Front 1

What are some characteristics of adenovirus?

Back 1

ds DNA; non-enveloped icosahedral

Front 2

What is the most common viral cause of pharyngitis?

Back 2

adenovirus

Front 3

What is the purpose of the fiber on the adenovirus?

Back 3

hemagglutinating activity; attachment to receptor

Front 4

What is the receptor in adenovirus?

Back 4

CAR; member if Ig superfamily

Front 5

How is adenovirus transmitted?

Back 5

aerosol, close contact, fecal-oral, direct or indirect to mucosa, fomites

Front 6

Where does adenovirus attack in humans?

Back 6

mucoepithelial cells in respiratory tract, GI tract, conjunctiva or cornea

Front 7

What does the subgenus of adenovirus tell you/

Back 7

functional components....F is most oncogenic

Front 8

What are the serotypes for acute respiratory disease of recruits?

Back 8

4,7,21

Front 9

How is a adenovirus detected?

Back 9

detection of antigen, virus isolation, serology

Front 10

What is CEP

Back 10

complement fixation test; clear area on slide will tell area of lysis

Front 11

Is there a vaccine for adenovirus?

Back 11

only for the acute respiratory distress syndrome serotypes

Front 12

What are some characteristics of coxsackie virus?

Back 12

cytolytic, enterovirus, naked, + stranded RNA, icosahedral capsid

Front 13

What is herpangina? and what causes it?

Back 13

vascular lesions in the throat caused by coxsackie virus

Front 14

s/s of herpangina

Back 14

sudden fever, sore throat, headache, dysphagia, malaise, white papules on posterior of palate

Front 15

characteristics of EBV

Back 15

only infects certain epithelial cells and B lymphocytes with receptor for C3d

Front 16

Where is EBV permissive and lytic?

Back 16

epithelial cells

Front 17

Where is EBV episomal and latent?

Back 17

B lymphocytes

Front 18

What does EBV cause?

Back 18

infectious mononucleosis and pharyngitis

Front 19

s/s mono

Back 19

fever, lymphadenopathy, sore throat with tonsillar exudates

Front 20

What is the most common cause of the common cold?

Back 20

rhinovirus

Front 21

clinical characteristics of common cold

Back 21

acute, afebrile

Front 22

When does rhinovirus cause the cold?

Back 22

summer/fall
30-50%

Front 23

When does coronavirus cause the cold?

Back 23

winter/spring
10-30%

Front 24

characteristics of the rhinovirus?

Back 24

nonenveloped icosahedral capsid; ss +sense RNA, replication in cytoplasm using RNA-dependent RNA polymerase

Front 25

What is resistant to drying and detergents?

Back 25

rhinovirus

Front 26

What is the receptor for rhinovirus?

Back 26

ICAM-1

Front 27

how is rhinovirus transmitted?

Back 27

fecal-oral, direct contact, aerosols, fomites

Front 28

incubation for rhiniovirus?

Back 28

1-2 days with 7 day illness duration

Front 29

characteristics of coronavirus

Back 29

+ sense ssRNA, enveloped

Front 30

Where does coronavirus infect?

Back 30

ciliated epithelium of URT, leading to cell damage and inflammation

Front 31

How is coronavirus trasmitted?

Back 31

airborne droplets to the nasal mucosa

Front 32

What are most cases of acute rhinosinusitis caused by?

Back 32

rhinovirus and adenovirus

Front 33

What are the bacterial pathogens for acute rhinosinusitis?

Back 33

S. pneumoniae and H. influenza

Front 34

What does parainfluenza cause?

Back 34

common cold
bronchitis
croup

Front 35

s/s laryngitis

Back 35

hoarseness, weak voice, tickling sensation and rawness of throat, sore throat, dry throat and cough

Front 36

Who usually has croup?

Back 36

children <4 with laryngitis

Front 37

s/s of croup

Back 37

barking cough, swelling around vocal cords

Front 38

differential for croup

Back 38

diphtheria, epiglottitis