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30 Cards in this Set

  • Front
  • Back

Airborne disease

Respiratory droplets

Portal of entry

Nose


Mouth


Ears


Eyes

Means of transmission

Airborne respiratory droplets

Streptococcal organisms

Streptococcus pyogenes


Chain of pus makers

2 classification methods

Hemolysis


Lansfield system

Alpha hemolysis

Green black

Group A strep

Beta-Clear


Encapsulated

Gamma

No change

Lansfield system

1933


A-O based on carbs in cell wall

Streptococcus pyogenes

Group A


Beta hemolytic


Encapsulated


Causes: step throat, Scarlet fever, rheumatic fever, puerperal fever, necrotizing fasciitis, glomerulonephritis

S. Pyogenes pathogenicity due to

Capsule


Pili


Adhesion factors


Exotoxin

Capsule

Prevents drying


Retards phagocytosis

Pili

Most humans have receptors in cilia or pharynx

Adhesion factor

M protein


Protrudes from cell wall


Adheres to pharyngeal tissue


Exotoxin

Makes blood come out capillaries

Scarlet fever

Strep throat plus rash


Treated with penicillin & clarithromycin

Erythrogenic exotoxin

Red toxin causes rash


Blood leaks out

Rheumatic fever

M protein resembles protein in heart valves and joint capsules

Necrotizing fascitis

Hyaluronidase


Spreads through connective tissue

Group B strep

Neonatal sepsis


Streptococcus agalactiae

Corynebacterium diphtheria

Aerobic, non motile, club shaped


Metachromatic granules give classic staining pattern


Exotoxin inhibits protein synthesis & creates pseudomembrane


Treatment penicillin and arithromycin and antitoxin


Russia Asia


Meningitis

Any organism can cause it


Most dangerous bacterial (virus, fungi, protozoan, bacterial)


Respiratory droplets


Meninges of spine and brain

Neisseria meningitides

Endotoxin is lipid A


In saliva

Streptococcus pneumonia

High mortality

Haemophilus influenza

Misnamed


Hib vaccine w/ DTap as tetramune


Usually stays in URT


If enters blood stream can easily cross blood brain barrier

Meningococcemia

Rash


Limb damage

Bordetella pertussis

Tissue: bronchial tubes & lungs


Fills aveoli spaces , oxygen exchange is diminished


100 day


Adhere to cillia in URT


Paralyze cillia, non productive cough


Mucus descends to lungs

Streptococcus agalctiae

Group B strep


Neonatal sepsis


Triggers 85% of premi

Gv

G

3 stages of pertussis

Catarrhal - malaise, low grade fever, increasing sever cough


Paroxysms - major events of coughing, inhale over closed glottis "whoop" sound, vomiting


Convalescent - sporadic coughing, 100 days


aP- part of DTaP


Erythromycin - reduces length and severity


Adults need booster Tdap