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12 Cards in this Set

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  • Back
Fleming discovered penicillin while working with ___________.
Stapholococcus
True or False:
Fleming was able to purify the compound.
False
Chain and Florey successfully isolated ___________. Waksman isolated _____________ from soil bacteria.
Penicillin
Streptomycin
Most modern antibiotics come from organisms living in the __________.
Soil
In some cases, drugs are modified to produce new traits, these are termed _______-__________.
Semi-synthetic
Selective __________ refers to antimicrobials being more harsh on microes than on humans. Why is this?
Toxicity
Interferes with processes common to bacterial cells and not human ones.
Toxicity of a drug is expressed through __________ ___________.
Theraputic index
High theraputic index = _______ toxic to humans.
Less
The therapeutic index is the lowest dose toxic to the patient divided by....
The dose usually given for treatment.
Drugs may kill or inhibit bacterial growth:
Inhibit = Bacterio________
Kill = Bacterio__________
Inhibit = Bacteriostatic
Kill = Bacteriocidal
_________ spectrum drugs work on Gram +'s only OR Gram -'s only.
Narrow
Broad spectrum drugs work on Gram + and Gram -, but a disadvantage is disruption to the _________ ________ of the body.
Normal flora