Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
*analog
|
a compound whose configuration closely resembles another compound required for cellular reactions
|
|
|
*what are the long-term effects of drugs that block transcription?
|
seizures, brain disturbances
|
|
|
*what effect do nitrogen-base analogs have an viruses?
|
the analog competes for a site in the replicating DNA; once it is in, replication of the strand stops and the viral life cycle is disrupted
|
|
|
*where does interferon come from?
|
produced by fibroblasts and leukocytes; also produced by virally infected cells
|
|
|
*summarize the biological actions of interferon
|
antiviral and anticancer
|
|
|
*R factors
|
resistance factors are plasmids that code for drug resistance
|
|
|
what is the name of plasmids that code for drug resistance?
|
R (resistance) factors
|
|
|
* list the five basic mechanisms of drug resistance
|
(1) inactive drug; (2) decrease permeability; (3) activate drug pumps; (4) change the drug binding site; (5) use alternate metabolic pathway
|
|
|
*list two reasons why biofilms are more drug resistant
|
(1) drug cannot penetrate into biofilm; (2) microbes communicate in the regulation of resistance mechanisms such as drug pumps
|
