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14 Cards in this Set
- Front
- Back
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what does adenovirus cause
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-pharyngitis
-common cold -acute respiratory distress |
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what are characteristics of adenovirus
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-ds DNA
-non-env, icosahedral -mainly polumorphic with 47 serotypes known -classified into 6 denera A-F |
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what kind of activity does adenovirus have that helps it attach to receptor
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fiber-hemagglutinating activity
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what receptor is required by adenovirus and what is unique about it
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it req CAR
and the unique thing is the same receptor is required by coaxake virus -receptor helps attach to Ig superfamily |
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what is the mechanism of infection w/adenovirus
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-man reservoir
-aerosol -direct, close contact -mucosa involved -fomite |
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what is the pathogenesis and immunity of adenvirus
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tropism, effects many cells like mucoepithelial cells of GI tract , conjunctiva, cornea
-lytic, persistent and latent infections |
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what are the clinical diseases associated with bordetella pertussis
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URI
ARd and pneumonia |
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what is unique about adenovirus transmission
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it can be spread by swimming in poorly cl pools
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what is mode of transmission overall
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virus can get in through the eye and upper respiratory but it doesn't stays localized, it spreads
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what are respiratory syndromes that are caused by adenovirus subgenera
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acute respiratory disease of recruits 4,7, 14, 21
pharyngits pharyngoconjunctival fever pneumonia pertussis like syndromes severe disease in AIDS |
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what is the lab diagnosis against adenovirus
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-Ag detection
-location= rapidly isolated from nasopharyngeal aspirates -serology= a retrospective diagnosis can be made via ELISA. CFT used the most |
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does adenovrius have CPE (cytopathic effect)
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yes, it has dark basophillic inclusions w/in the nuclei represent accumulated viral protein at the site of virus assembly
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what is the treatment and prevention of adenovirus
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-there is no antiviral therapy
-there is a vaccine available against adult respiratory distress syndrome 4,7,14,21 |
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who should be given 4,7,21 vaccine
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military recruits due to close quarters
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