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57 Cards in this Set
- Front
- Back
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What agents affect the bacterial cell wall?
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Penicillins, Cephalosporins, Vancomycin, Teicoplanin, Monobactams, & Thienamycins.
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What agents inhibit protein synthesis by attacking the 50S ribosome?
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Chloramphenicol, Erythromycin, Clindamycin, and Clarithromycin.
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What agents inhibit protein synthesis by attacking the 30S ribosome?
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Gentamicin, Tobramycin, Amikacin, Netilmicin, and Tetracycline group
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What agent inhibits the initiation of protein synthesis?
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Zyvox (Oxazolidinone)
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What agents impede replication of genetic information?
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Quinolones, Rifampin, and metronidazole.
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What agent works by attacking DNA-gyrase?
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The Quinolones: Nalidixic acid, Norfloxacin, and Ciprofloxacin.
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What agent can be used for all anerobes?
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Metronidazole: works by impeding replication of genetic information. It gets reduced in the bacteria and creates free radicals destroying the DNA.
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What agents affect the cell membrane of bacteria?
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Polymyxins: Polymyxin E (colistin) -can be synergistic with penicillins.
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What agents affect the cell membrane of fungi?
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Antifungals: Nystatin, Amphotericin B, Imidazoles (miconazole, Ketoconazole), Triazoles (Itraconazole)
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What agents affect intermediary metabolism?
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Trimethoprim (UTI), Sulfonamides (synergy w trimethoprim for UTI), Isoniazid (TB), Aminosalicylic acid (TB), and Sulfone (leprosy).
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Where do the penicillins act on bacteria?
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The Cell Wall
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What is methicillin?
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Penicillin and resistant to beta lactamase.
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What is Carbenicillin?
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Penicillin, not resistant to beta lactamase.
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What is ampicillin?
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Penicillin, not resistant to beta lactamase.
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What is Amoxicillin?
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Penicillin, not resistant to beta lactamase.
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What is Ticeracillin?
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Penicillin, not resistant to beta lactamase.
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What is Azlocillin?
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Penicillin, not resistant to beta lactamase.
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What is Amdinocillin?
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Penicillin, not resistant to beta lactamase.
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Whater is Piperacillin?
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Penicillin, not resistant to beta lactamase.
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What is Mezlocillin?
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Penicillin, not resistant to beta lactamase.
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What is Nafcillin?
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Penicillin, resistant to beta lactamase.
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What is Oxacillin?
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Penicillin, resistant to beta lactamase.
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What is Cloxacillin?
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Penicillin, resistant to beta lactamase.
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What is Dicloxacillin?
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Penicillin, resistant to beta lactamase.
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What is Flucloxacillin?
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Penicillin, resistant to beta lactamase.
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What is Temocillin?
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Penicillin, resistant to beta lactamase.
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What are Cephalosporins?
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They are antibiotics that affect the cell wall. Sometimes will not cross blood brain barrier.
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What are vancomycin and teicoplanin?
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They are antibiotics that affect the cell wall and work against gram positive bacteria and are beta lactamase resistant.
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What is Monobactams?
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Aztreonam, beta lactamase resistant, and good against enterobacteria.
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What is Thienamycin?
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Imipenem, beta lactamase resistant with great spectrum.
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What is Chloramphenicol?
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Antibiotic that inhibits protein synthesis by attacking 50S ribosome.
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What is Erythromycin?
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Antibiotic that inhibits protein synthesis by attacking 50S ribosome.
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What is Clarithromycin?
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Antibiotic that inhibits protein synthesis by attacking 50S ribosome.
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What is Clindamycin?
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Antibiotic that inhibits protein sythesis by attacking 50S ribosome.
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What is Gentamicin?
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Antibiotic that inhibits protein synthesis by attacking the 30S ribosome.
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What is Tobramycin?
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Antibiotic that inhibits protein synthesis by attacking the 30S ribosome.
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What Amikacin?
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Antibiotic that inhibits protein synthesis by attacking the 30S ribosome.
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What is Netilmicin?
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Antibiotic that inhibits protein synthesis by attacking the 30S ribosome.
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What is tetracycline?
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Group includes tetracycline, doxycyclen, and minocyclene and are antibiotics that attack the 30S ribosome preventing protein synthesis.
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What is Zyvox?
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AKA Oxazolidinone, antibiotic that inhibits the initiation of protein synthesis.
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What is Nalidixic acid?
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Quinolone, antibiotic that impedes replication of genetic information.
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What is Norfloxacin?
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Quinolone, antibiotic that impedes replication of genetic information.
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What is ciprofloxacin?
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Quinolone, antiobiotic that impedes replication of genetic information.
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What are Quinolones used for ?
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UTI's, Gram-positive bacteria, Pseudomonas
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What is Rifampin?
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Antibiotic that impedes replication of genetic information. Used TB.
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What is metronidazole?
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Antibiotic that impedes replication of genetic information. Works on all anerobes, and good for amebiasis, giardiasis.
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What is polymixin E?
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Polymyxin that is synergistic with penicillins, and attacks cell membranes.
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How do antifungals work?
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They work by attacking cell membranes.
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What is Nystatin?
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Antifungal, that attacks the cell membrane.
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What is Amphotericin B?
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Antifungal, that attacks the cell membrane.
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What is imidazoles?
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Antifungals, like miconazole and ketoconazole. Attack the cell membrane.
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What is Itraconazole?
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It is a triazole, which is an antifungal. Attacks the cell membrane.
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What is Trimethoprim?
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Antibiotic that attacks the intermediary metabolism. Used for UTI's.
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What are sulfonamides?
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Antibiotics that attack the intermediary metabolism. Has synergy with trimethoprim with UTI treatment.
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What is INH (Isoniazid)?
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Antiobiotic used for TB, and attacks the intermediary metabolism.
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What is Aminosalicylic acid?
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Antibiotic used for TB and attacks the intermediary metabolism.
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What is Sulfone?
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Antibiotic used for Leprosy and attacks the intermediary metabolism.
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