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19 Cards in this Set

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  • Back
Life cycle of Fasciola hepatica?
human ingests aquatic plant w/metacercariae

excyst in duodenum, reproduce; human poops eggs into H2O --> miracidia --> snail --> free swimming cercariae --> metacercariae on aquatic plant.
Life cycle of Fasciolopsis buski?
same as F. hepatica but definitive host may be pig instead of sheep.
Difference between F. hepatica and F. buski adults?
F. buski is larger (up to 75mm) and occurs in pigs

F. heptaica up to 30mm and occurs in sheep livers
Which trematodes have two intermediate hosts? What are the species and their hosts?
Chlonorchis sinensis: snail, freshwater fish

Paragonimus westermani: snail, freshwater crustacean
Where does Fasciola hepatica prefer to infect?
liver. metacercariae migrate from intestine --> bile duct
Where is Fasciola hepatica endemic?
Europe, Middle East, Asia

places they eat watercress
How to distinguish between Fasciola hepatica, Paragonimus westermani, and Diphyllobotrium latum ova?
SIZE!

F. hepatica (140um) > P. westermani (90um) > D. latum (70um)

D. latum thinner walls

F. hepatica walls more irregular
Where is Paragonimus westermani endemic?
SE Asia, Japan

places they eat raw crustaceans
Preferred target of Schistosoma mansoni?
lower digestive tract
Preferred target of Schistosoma hematobium?
bladder
Preferred target of Schistosoma japonicum?
upper digestive tract
Rank the trematodes in order of size.
Fasciolopsis buski > Fasciola hepatica > Chlonorchis sinensis > Paragonimus westermani
Geographic distribution of S. mansoni?
Slave trade!

West Africa, Gold/Ivory Coast, South America (BRAZIL), Carribean
Geographic distribution of S. hematobium?
Africa, Middle east

Portugal/Spain due to large Muslim population from Middle East
Geographic distribution of S. japonicum?
Southeast Asia

Hyper-endemic in Philippines
Hepatic Portal Pipestem Fibrosis is characteristic of invasion by which trematode?
S. japonicum (S. mansoni also)

worm resides in blood; lays eggs --> go to intestine OR to liver --> cirrhosis!
Symptoms of infection by Schistosoma japonicum?
hepato and splenomegaly
abdominal edema due to liver cirrhosis
emaciation due to loss of metabolic regulation (liver)
How to dx infection by Schistosoma spp.?
S. mansoni & japonicum: ova in feces, mucosal scrapings, ulcer detected by colonoscopy
S. hematobium: ova in URINE at 1PM
When is the best time to collect urine from a suspected Schistosomiasis patient?
1:00 PM