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20 Cards in this Set
- Front
- Back
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372. DOC for a pt w/ travel hx (back from the tropics), who has flu-like symptoms; splenomegaly; lab: CBC: anemia, thrombocytopenia, hypoglycemia. Blood smear: enlarged RBCs and Schuffner dots.
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mefloquine + primaquine
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373. Which drug is contraindicated in specific Tx of liver form of malaria in pts w/ G6PD deficiency?
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Primaquine
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374. DOC for a pt w/ travel hx (back from the tropics), who has flu-like symptoms (fever > 103oF), seizure, hyperparasitemia (>2.5% of RBC), pulmonary edema, or renal failure, or severe anemia?
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Quinidine and doxycycline.
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375. Cause of malaria-like illness in an immunosuppressed pt w/o travel hx; lab: blood smear has cross-over rings in the RBCs?
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Babesia spp.
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376. A pt from S. America has a week-long fever, anorexia, lymphadenopathy, mild hepatosplenomegaly, and myocarditis; a nodular lesion on the arm. Blood smear should reveal motile species of what?
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Trypanosoma cruzi
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377. Cause of a chronic-stage systemic dz w/ cardiomyopathy, megaesophagus, megacolon, and weight loss in a pt from S. America, who does not respond to nifurtimox.
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Trypanosoma cruzi
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378. Cause of protracted fever and Crohn’s, celiac dz, ocular problems, and lymphadenopathy; duodenal biopsy demonstrating foamy macrophages in lamina propria?
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Tropheryma whipplei
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379. Clinical Dx of painless papule (on arms, face, or chest), then vesicles/bullae, then black eschar + edema evolving over 3-5d associated with animal exposure is
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Cutaeneous anthrax
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380. Cutaneous anthrax can be treated in 7-10 days with
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Ciprofloxacin
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381. Animal exposure or biowarfare-associated fever, chills, sweats, GI sx, cough, malaise, chest pain, but no coryza (first 3-4d); then sepsis; CXR: wide mediastinum and bloody pleural effusion. Blood culture should yield
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Bacillus anthracis
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382. Inhalation anthrax is treated with
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Fluoroquinolone > doxycycline
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383. Need to treat inhalation anthrax 60-100 days because
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Spores persist in vivo 30 days
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384. PxPr to prevent inhalation anthrax via aerosolized spores from powder particle size < 10 microns requires
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Cipro for 60 days
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385. Species of Clostridium that causes afebrile, systemic toxic diseases in infants (honey), and in adults foodborne (meat, canned vegetables), wound (injected), iatrogenic (cosmetic) is
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C. botulinum
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386. Many pts w/ flaccid paralysis; unusual Clostrium botulium types (not A, B or E), common geography without common food source are clues to
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bioterrorism
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387. Aerobic small slender gram-negative rod, erroneously identified as Pseudomonas sp., which causes glanders in horses and rarely humans; may be used in bioterrorism is
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Burkholderia mallei
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388. Small, pleomorphic, aerobic Gram-neg rod that causes pathophysiology: 1) bite/abrasion (acquired from tick exposure or contact with rabbits) → nodule/ulcer → node → sepsis, or 2) inhalation (bioterrorism) → acute fever, dry cough. CXR: infiltrates + hilar adenopathy, is
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Francisella turlarensis
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389. Hx of acute fever, myalgias, remorrhagic rash, conjunctivitis, pharyngitis, headache, diarrhea, and thrombocytopenia in bioterrorism indicates
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Viral hemorrhagic fever (e.g., Marburg, Ebola)
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390. Aerobic, Gram-neg bipolar rod, which causes pathophysiology of (a) painful lymphadenitis, fever, chills, headache (after exposure to rodents, rabbits or fleas) (b) sepsis; (c) pneumonic (post bubo or epidemic): severe, often with hemoptysis and dyspnea, is
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Yersinia pestis
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391. Hx of sudden fever ≥ 39°C , homogeneous vesiculo-pustular rash (unlike common viral exanthems) in multiple pts is caused by
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Variolla major virus (small pox)
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